The shape of attention: How cognitive goals sculpt cortical representation of speech.

Kavli Affiliate: Mounya Elhilali | Authors: Moïra-Phoebé Huet and Mounya Elhilali | Summary: Perception requires more than passive sensing—it involves prioritizing the features most relevant to ongoing cognitive goals, a process guided by selective attention. A central question is whether attention operates by enhancing all features of a selected target, or by optimizing neural encoding […]


Continue.. The shape of attention: How cognitive goals sculpt cortical representation of speech.

Population-level morphological analysis of paired CO2- and odor-sensing olfactory neurons in D. melanogaster via volume electron microscopy

Kavli Affiliate: Mark Ellisman | Authors: Jonathan Choy, Shadi Charara, Kalyani Cauwenberghs, Quintyn McKaughan, Keun-Young Kim, Mark Ellisman and Chih-Ying Su | Summary: Dendritic morphology is a defining characteristic of neuronal subtypes. In Drosophila, heterotypic olfactory receptor neurons (ORNs) expressing different receptors display diverse dendritic morphologies, but whether such diversity exists among homotypic ORNs remains […]


Continue.. Population-level morphological analysis of paired CO2- and odor-sensing olfactory neurons in D. melanogaster via volume electron microscopy

Spatiotemporal transcriptomic analysis during cold ischemic injury to the murine kidney reveals compartment-specific changes

Kavli Affiliate: Jean Fan | Authors: Srujan Singh, Shishir Kumar Patel, Ryo Matsuura, Dee Velazquez, Zhaoli Sun, Sanjeev Noel, Hamid Rabb and Jean Fan | Summary: Kidney transplantation is the gold standard treatment strategy for end-stage renal disease. Deceased donor kidneys usually undergo cold storage until kidney transplantation, leading to cold ischemia injury that may […]


Continue.. Spatiotemporal transcriptomic analysis during cold ischemic injury to the murine kidney reveals compartment-specific changes

Optimized Theta Burst Stimulation with Extended Intervals Enhances Excitatory-Inhibitory Balance

Kavli Affiliate: Dhakshin Ramanathan and Jyoti Mishra | Authors: Morteza Salimi, Milad Nazari, Jonathan Mishler, Jennifer Rodger, Sahar Jomehpour, Jyoti Mishra and Dhakshin Ramanathan | Summary: Varying inter-train intervals (ITIs) during theta burst stimulation (TBS) differentially modulates neuronal activity in the medial prefrontal cortex. Short ITIs (e.g., ITI 4 s) induce strong glutamatergic excitation but […]


Continue.. Optimized Theta Burst Stimulation with Extended Intervals Enhances Excitatory-Inhibitory Balance

Sequential transcriptional gates in the thalamo-cortical circuit coordinate memory stabilization

Kavli Affiliate: Priya Rajasethupathy | Authors: Andrea Terceros, Celine Chen, Yujin Harada, Tim Eilers, Millennium Gebremedhin, Richard P Koche, Pierre-Jacques Hamard, Roshan Sharma and Priya Rajasethupathy | Summary: The molecular mechanisms that enable memories to persist over long time-scales from days to weeks and months are still poorly understood. To develop insights we created a […]


Continue.. Sequential transcriptional gates in the thalamo-cortical circuit coordinate memory stabilization

Neuroticism Heterogeneity Through Item-Level Associations in Resting-State Functional Connectivity

Kavli Affiliate: Wesley Thompson | Authors: Masaya Misaki, Chun Chieh Fan, Wesley K Thompson, Heekyeong Park, Bohan Xu and Martin M Paulus | Summary: Neuroticism is characterized by emotional instability and increased susceptibility to stress-related disorders. While traditionally treated as a unitary construct, growing evidence suggests that neuroticism is heterogeneous in both its genetic basis […]


Continue.. Neuroticism Heterogeneity Through Item-Level Associations in Resting-State Functional Connectivity

Epigenetic mechanisms governing cell type specific somatic expansion and toxicity in Huntington’s disease

Kavli Affiliate: Nathaniel Heintz | Authors: Matthew Baffuto, Kert Mätlik, Isaac Ilyashov, Maria Esterlita Siantoputri, Hasnahana Chetia, Yurie Harada, Erika Sipos, Paul Darnell, Laura Kus, Thomas Carroll, Douglas Barrows, Christina Pressl, Nicholas Didkovsky and Nathaniel Heintz | Summary: Huntington’s disease (HD) is characterized by neuronal dysfunction and degeneration that varies markedly by brain region and […]


Continue.. Epigenetic mechanisms governing cell type specific somatic expansion and toxicity in Huntington’s disease

Aperiodic neural dynamics define a novel signature of glioma-induced excitation-inhibition dysregulation

Kavli Affiliate: Edward Chang | Authors: Youssef E Sibih, Abraham O Dada, Emily E Cunningham, Niels Olshausen, Jasleen Kaur, Velmurugan Jayabal, Sena Oten, Sanjeev Herr, Cesar N Gonzales, Andy Daniel, Saritha Krishna, Vardhaan S Ambati, Alexander A Aabedi, Gray Umbach, Kanish Mirchia, Poortata Lalwani, Edward F Chang, David R Raleigh, Srikantan Nagarajan, David Brang and […]


Continue.. Aperiodic neural dynamics define a novel signature of glioma-induced excitation-inhibition dysregulation

Hebb’s Vision: The Structural Underpinnings of Hebbian Assemblie

Kavli Affiliate: Reza Abbasi Asl | Authors: Julian A Wagner-Carena, Sai Kate, Trevor Riordan, Reza Abbasi-Asl, Joe Aman, Adam Amster, Agnes L Bodor, Derrick Brittain, JoAnn Buchanan, Michael A Buice, Daniel J Bumbarger, Forrest Collman, Nuno Macarico da Costa, Daniel J Denman, Saskia EJ de Vries, Emily Joyce, Dan Kapner, Chase W King, Josh D […]


Continue.. Hebb’s Vision: The Structural Underpinnings of Hebbian Assemblie

GABAergic signaling by VIP interneurons gates running-dependent visual recovery in the adult brain

Kavli Affiliate: Michael Stryker | Authors: Anna Lebedeva, Friedrich Kling, Benjamin Rakela, Michael P Stryker and Yujiao Jennifer Sun | Summary: Experience-dependent plasticity in the adult visual cortex is enhanced by locomotion, a process mediated by vasoactive intestinal peptide (VIP)-expressing interneurons. While VIP interneurons are known to signal through both Gamma-aminobutyric acid (GABA) and VIP […]


Continue.. GABAergic signaling by VIP interneurons gates running-dependent visual recovery in the adult brain