Kavli Affiliate: Michael Miller | Authors: Zinan Zhou, Lovelace J Luquette, Guanlan Dong, Junho Kim, Jayoung Ku, Kisong Kim, Mingyun Bae, Diane D Shao, Bezawit Sahile, Michael B Miller, August Yue Huang, Peter J Park, Clotilde Lagier-Tourenne, Eunjung Alice Lee and Christopher A Walsh | Summary: Amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheimer’s […]
Kavli Affiliate: Michael Miller | Authors: Guanlan Dong, Chanthia C Ma, Shulin Mao, Samuel M Naik, Katherine Sun-Mi Brown, Gannon A McDonough, Junho Kim, Samantha L Kirkham, Jonathan Cherry, Madeline Uretsky, Elizabeth Spurlock, Ann McKee, August Yue Huang, Michael B Miller, Eunjung Alice Lee and Christopher A Walsh | Summary: Chronic traumatic encephalopathy (CTE) is […]
Kavli Affiliate: Xingde Li | Authors: Fengquan Liu and Xingde Li | Summary: Dispersion mismatch in optical coherence tomography (OCT) is typically addressed through either physical or digital compensation. In this study, we investigate the impact of dispersion on OCT detection sensitivity and compare the effectiveness of physical and digital compensation across varying degrees of […]
Kavli Affiliate: Alexandra Nelson and Anatol Kreitzer | Authors: Katerina L Rademacher, Zak Doric, Dominik Haddad, Aphroditi Mamaligas, Szu-Chi Liao, Rose Creed, Kohei Kano, Zac Chatterton, Yuhong Fu, Joseph H Garcia, Victoria Vance, Yoshitaka Sei, Anatol Kreitzer, Glenda Halliday, Alexandra Nelson, Elyssa Margolis and Ken L Nakamura | Summary: Parkinson’s disease (PD) is characterized by […]
Kavli Affiliate: Jyoti Mishra and Dhakshin Ramanathan | Authors: Morteza Salimi, Milad Nazari, Jonathan Mishler, Mishra Jyoti and Dhakshin Ramanathan | Summary: Background Repetitive brain stimulation is hypothesized to bidirectionally modulate excitability, with low-frequency trains decreasing and high-frequency (>5 Hz) trains increasing activity. Most insights on the neuroplastic effects of repetitive stimulation protocols stem from […]
Kavli Affiliate: Winrich Freiwald | Authors: Lucas Y Tian, Kedar U Garzón, Adam G Rouse, Mark AG Eldridge, Marc H Schieber, Xiao-Jing Wang, Joshua B Tenenbaum and Winrich A Freiwald | Summary: At the core of intelligence is proficiency in solving new problems, including those that differ dramatically from problems seen before. Problem-solving, in turn, […]
Kavli Affiliate: Vincent Ferrera | Authors: Alec J. Batts, Robin Ji, Sua Bae, Fotios N. Tsitsos, Sergio Jiménez-Gambín, Nancy Kwon, Samantha L. Gorman, Deny Tsakri, Rebecca L. Noel, Jonas Bendig, Daniella A. Jimenez, Melody DiBenedetto, Sofia A. Del Castillo, Filimon B. Keleta, James Caicedo, Alexander Romanov, Colleen T. Curley, Yulia Dzhashiashvili, Greglynn D. Walton-Gibbs, Bradley […]
Kavli Affiliate: Peter Walter | Authors: Kristof Torkenczy, Lucas C Reineke, Sean W Dooling, Benjamin W Henderson, Daniel Itzhak, Benjamin Yang, Dongze He, Richard M Myers, Peter Walter, Stefka Tyanova and Mauro Costa-Mattioli | Summary: Persistent activation of the integrated stress response (ISR) is a major driver of cognitive decline in both neurodevelopmental and neurodegenerative […]
Kavli Affiliate: Yifan Cheng | Authors: Junrui Li, Yifei chen, Shawn Zheng, Angus McDonald, John W. Sedat, David A. Agard and Yifan Cheng | Summary: With technological advancements in recent years, single particle cryogenic electron microscopy (cryo-EM) has become a major methodology for structural biology. Structure determination by single particle cryo-EM is premised on randomly […]
Kavli Affiliate: Jin Kang | Authors: Mandeep S Singh, Shoujing Guo, Christopher B Toomey, Minda M McNally, Sarah Harris-Bookman, Kang V Li, Dzhalal Agakishiev, Shuwen Wei, Soohyun Lee, Kathleen Perrino, Kevin C Wolfe and Jin Kang | Summary: Purpose Regenerative therapies for retinal diseases include cell and gene therapy modalities that are targeted to the […]