Seizure-induced Transient Disruptive Changes in Brain Microstructure

Kavli Affiliate: Anders Dale | Authors: Akihiro Takamiya, Frank Riemer, Vera Jane Erchinger, Max Korbmacher, Hauke Bartsch, Olga Therese Ousdal, Ivan Maximov, Anders Dale, Louise Emsell, Ketil Joachim Oedegaard, Ute Kessler and Leif Oltedal | Summary: A leading hypothesis for the mechanisms of electroconvulsive therapy (ECT) posits an initial disruptive effect followed by enhanced neuroplasticity. […]


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Diverse and Flexible Strategies Enable Successful Cooperation in Marmoset Dyads

Kavli Affiliate: Anirvan Nandy | Authors: Olivia C Meisner, Weikang Shi, Amrita Nair, Gargi Nandy, Monika P Jadi, Anirvan S Nandy and Steve W. C. Chang | Summary: In humans, cooperation relies on advanced social cognition, but the extent to which these mechanisms support cooperation in nonhuman primates remains unclear. To investigate this, we examined […]


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Synaptic vesicles that store monoamines and glutamate differ in protein composition.

Kavli Affiliate: Robert Edwards | Authors: Hrach Asmerian, Alexia J. Diaz, Hongfei Xu, Juan A Oses-Prieto, Jacob Alberts, Anna M. Sanetra, Barathan Gnanabharathi, Noah Carr, Alma L. Burlingame, Robert H. Edwards and Katlin Silm | Summary: Neuromodulators such as the monoamines are known to differ from classical neurotransmitters like glutamate in the time scale of […]


Continue.. Synaptic vesicles that store monoamines and glutamate differ in protein composition.

Dynamics of auditory word form encoding in human speech cortex

Kavli Affiliate: Edward Chang | Authors: Yizhen Zhang, Matthew K Leonard, Laura Gwilliams, Ilina Bhaya-Grossman and Edward F Chang | Summary: When we hear continuous speech, we perceive it as a series of discrete words, despite the lack of clear boundaries in the acoustic signal. The superior temporal gyrus (STG) encodes phonetic elements like consonants […]


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Theory of interaction between untuned modulatory inputs and tuned sensory inputs

Kavli Affiliate: Kenneth Miller | Authors: Tuan Nguyen, Agostina Palmigiano and Kenneth D Miller | Summary: How does the brain integrate sensory inputs with non-feature-tuned signals, such as those arising from behavioral state changes or neuromodulation? Here, we show that the dynamics of disordered E/I networks with structured, feature-dependent connectivity can be well characterized by […]


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Presynaptic vesicles supply membrane for axonal bouton enlargement during LTP

Kavli Affiliate: Terrence Sejnowski | Authors: Patrick Leavey, Lizhi Jiang, Nicole Pannullo, Clayton Santiago and Seth BlackshawLyndsey M Kirk, Guadalupe C Garcia, Dakota C Hanka, Kyle Zatyko, Thomas M Bartol, Terrence J Sejnowski and Kristen M. Harris | Summary: Long-term potentiation (LTP) induces presynaptic bouton enlargement and a reduction in the number of synaptic vesicles. […]


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Overexpression of Meis factors in late-stage retinal progenitors yields complex effects on temporal patterning and neurogenesis.

Kavli Affiliate: Seth Blackshaw | Authors: Patrick Leavey, Lizhi Jiang, Nicole Pannullo, Clayton Santiago and Seth Blackshaw | Summary: The vertebrate retina serves as a model for studying neurogenesis and cell fate specification, with retinal progenitor cells following a tightly regulated temporal sequence to generate distinct cell types. Meis1 and Meis2 are transcription factors implicated […]


Continue.. Overexpression of Meis factors in late-stage retinal progenitors yields complex effects on temporal patterning and neurogenesis.

Short-term gonadal cultures are sufficient for germline transmission in a songbird

Kavli Affiliate: Erich Jarvis | Authors: Matthew T Biegler, Elijah Harter, Asha V Sidhu, Christina Szialta, Gillian Durham, Lotem Tchernichovski, Paul Collier, Ji-Dung Luo, Wei Wang, Ryan MacIsaac, Kirubel Belay, Thomas Carroll, Anna L Keyte and Erich D Jarvis | Summary: Primordial germ cells (PGCs) are germline stem cells that develop into sperm or egg […]


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ARAP2 regulates responses to interferon-gamma by restricting SOCS1

Kavli Affiliate: Jean-Laurent Casanova | Authors: Narelle Keating, Karen Doggett, Grace Bidgood, Lizeth G Meza Guzman, Laura Dagley, Kunlun Li, Anna Gabrielyan, Carolina Alvarado, Bailey Williams, Benjamin Broomfield, Brigette Duckworth, Colin Hockings, Jumana Youssef, Evelyn Leong, Rhiannon Morris, Andrew Kueh, Alexandra Garnham, Jean-Laurent Casanova, Stephanie Boisson-Dupuis, Jeffrey Babon, Edmond Linossi, Michelle D Tate, Joanna R. […]


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No Disconnection Syndrome after Near-Complete Callosotomy

Kavli Affiliate: Michael Miller | Authors: Selin Bekir, Johanna L. Hopf, Theresa Paul, Valerie M. Wiemer, Tyler Santander, Henri E. Skinner, Anna Rada, Friedrich G. Woermann, Thilo Kalbhenn, Barry Giesbrecht, Christian G. Bien, Olaf Sporns, Michael S. Gazzaniga, Lukas J. Volz and Michael B. Miller | Summary: Sensorimotor processing in the human brain is largely […]


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