Kavli Affiliate: Richard Huganir | Authors: William Dylan Hale, Thomas C. Sudhof and Richard L. Huganir | Summary: In multicellular organisms, cell-adhesion molecules connect cells into tissues and mediate intercellular signaling between these cells. In vertebrate brains, synaptic cell-adhesion molecules (SAMs) guide the formation, specification, and plasticity of synapses. Some SAMs, when overexpressed in cultured […]
Kavli Affiliate: Irfan Siddiqi | First 5 Authors: Akel Hashim, Stefan Seritan, Timothy Proctor, Kenneth Rudinger, Noah Goss | Summary: The promise of quantum computing depends upon the eventual achievement of fault-tolerant quantum error correction, which requires that the total rate of errors falls below some threshold. However, most contemporary methods for benchmarking noisy quantum […]
Kavli Affiliate: Yi Zhou | First 5 Authors: Yi Zhou, Shan Hu, Zimo Sheng, , | Summary: The densest subgraph problem (DSG) aiming at finding an induced subgraph such that the average edge-weights of the subgraph is maximized, is a well-studied problem. However, when the input graph is a hypergraph, the existing notion of DSG […]
Kavli Affiliate: Jia Liu | First 5 Authors: Menglu Yu, Bo Ji, Hridesh Rajan, Jia Liu, | Summary: Powered by advances in deep learning (DL) techniques, machine learning and artificial intelligence have achieved astonishing successes. However, the rapidly growing needs for DL also led to communication- and resource-intensive distributed training jobs for large-scale DL training, […]
Kavli Affiliate: Yi Zhou | First 5 Authors: Runhua Xu, Nathalie Baracaldo, Yi Zhou, Ali Anwar, Swanand Kadhe | Summary: Federated learning has emerged as a privacy-preserving machine learning approach where multiple parties can train a single model without sharing their raw training data. Federated learning typically requires the utilization of multi-party computation techniques to […]
Kavli Affiliate: John Reynolds, Kenneth Miller | Authors: Alessandro Sanzeni, Agostina Palmigiano, Tuan H Nguyen, Junxiang Luo, Jonathan J Nassi, John H Reynolds, Mark H Histed, Kenneth D Miller and Nicolas Brunel | Summary: The ability to observe the response of neural circuits to controlled optogenetic perturbations opens an unprecedented window into the mechanisms governing […]
Kavli Affiliate: Jonathan Rosner | Summary:The new strange pentaquarks observed by LHCb are very likely hadronic molecules consisting of $Ξ_c bar D$ and $Ξ_c bar D^*.$ We discuss the experimental evidence supporting this conclusion, pointing out the similarities and differences with the $P_c(4312)$, $P_c(4440)$ and $P_c(4457)$ pentaquarks in the non-strange sector. The latter clearly are […]
Kavli Affiliate: John Carlson | Authors: Wanyue Wang, Hany K M Dweck, Gaëlle J.S. Talross, Ali Zaidi, Joshua M Gendron and John R Carlson | Summary: The agricultural pest Drosophila suzukii differs from most other Drosophila species in that it lays eggs in ripe, rather than overripe, fruit. Previously we showed that changes in bitter […]
Kavli Affiliate: Takaki Komiyama | Authors: Saber Meamardoost, Eunjung Hwang, Mahasweta Bhattacharya, Chi Ren, Linbing Wang, Claudia Mewes, Ying Zhang, Takaki Komiyama and Rudiyanto Gunawan | Summary: The brain’s connectome continually rewires throughout the life of an organism. In this study, we sought to elucidate the operational principles of such rewiring by analyzing the functional […]
Kavli Affiliate: Gijsje Koenderink | Summary:One of the major challenges of bottom-up synthetic biology is rebuilding a minimal division machinery. The animal cell division apparatus is mechanically the simplest, in which an actin-based ring constricts the membrane, as compared to microbes and plant cells where a cell wall is involved. Furthermore, reconstitution of the actin […]