Single-cell analysis of prenatal and postnatal human cortical development

Kavli Affiliate: Arnold R. Kriegstein | Authors: Dmitry Velmeshev, Yonatan Perez, Zihan Yan, Jonathan E Valencia, David R Castaneda-Castellanos, Li Wang, Lucas Schirmer, Simone Mayer, Brittney Wick, Shaohui Wang, Tomasz J. Nowakowski, Mercedes Paredes, Eric J. J. Huang and Arnold Kriegstein | Summary: We analyze more than 700,000 single-nucleus RNA-seq profiles from 106 donors during […]


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Gravitational Wave Science in the Mid-Band with Atom Interferometers

Kavli Affiliate: Peter W. Graham | First 5 Authors: Sebastian Baum, Zachary Bogorad, Peter W. Graham, , | Summary: Gravitational Waves (GWs) have been detected in the $sim 100$ Hz and nHz bands, but most of the gravitational spectrum remains unobserved. A variety of detector concepts have been proposed to expand the range of observable […]


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Particle-hole asymmetric ferromagnetism and spin textures in the triangular Hubbard-Hofstadter model

Kavli Affiliate: Cheng Peng | First 5 Authors: Jixun K. Ding, Luhang Yang, Wen O. Wang, Ziyan Zhu, Cheng Peng | Summary: In a lattice model subject to a perpendicular magnetic field, when the lattice constant is comparable to the magnetic length, one enters the "Hofstadter regime," where continuum Landau levels become fractal magnetic Bloch […]


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Lysosomal TMEM106B interacts with galactosylceramidase to regulate myelin lipid metabolism

Kavli Affiliate: Stephen Strittmatter | Authors: Hideyuki Takahashi, Azucena Perez-Canamas, Hongping Ye, Xianlin Han and Stephen M. Strittmatter | Summary: TMEM106B is an endolysosomal transmembrane protein not only associated with multiple neurological disorders including frontotemporal dementia, Alzheimer’s disease, and hypomyelinating leukodystrophy but also potentially involved in COVID-19. Additionally, recent studies have identified amyloid fibrils of […]


Continue.. Lysosomal TMEM106B interacts with galactosylceramidase to regulate myelin lipid metabolism

Categorization dynamically alters representations in human visual cortex

Kavli Affiliate: John Serences | Authors: Margaret M Henderson, John T Serences and Nuttida Rungratsameetaweemana | Summary: Everyday visual search tasks require objects to be categorized according to behavioral goals. For example, when searching for an apple at the supermarket, one might first find the Granny Smith apples by separating all visible apples into the […]


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Real Effect or Bias? Best Practices for Evaluating the Robustness of Real-World Evidence through Quantitative Sensitivity Analysis for Unmeasured Confounding

Kavli Affiliate: Xiang Zhang | First 5 Authors: Douglas Faries, Chenyin Gao, Xiang Zhang, Chad Hazlett, James Stamey | Summary: The assumption of no unmeasured confounders is a critical but unverifiable assumption required for causal inference yet quantitative sensitivity analyses to assess robustness of real-world evidence remains underutilized. The lack of use is likely in […]


Continue.. Real Effect or Bias? Best Practices for Evaluating the Robustness of Real-World Evidence through Quantitative Sensitivity Analysis for Unmeasured Confounding

Unsupervised Contrast-Consistent Ranking with Language Models

Kavli Affiliate: Jing Wang | First 5 Authors: Niklas Stoehr, Pengxiang Cheng, Jing Wang, Daniel Preotiuc-Pietro, Rajarshi Bhowmik | Summary: Language models contain ranking-based knowledge and are powerful solvers of in-context ranking tasks. For instance, they may have parametric knowledge about the ordering of countries by size or may be able to rank reviews by […]


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Improving HEVC Encoding of Rendered Video Data Using True Motion Information

Kavli Affiliate: David Muller | First 5 Authors: Christian Herglotz, David Müller, Andreas Weinlich, Frank Bauer, Michael Ortner | Summary: This paper shows that motion vectors representing the true motion of an object in a scene can be exploited to improve the encoding process of computer generated video sequences. Therefore, a set of sequences is […]


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The thesan project: public data release of radiation-hydrodynamic simulations matching reionization-era JWST observations

Kavli Affiliate: Mark Vogelsberger | First 5 Authors: Enrico Garaldi, Rahul Kannan, Aaron Smith, Josh Borrow, Mark Vogelsberger | Summary: Cosmological simulations serve as invaluable tools for understanding the Universe. However, the technical complexity and substantial computational resources required to generate such simulations often limit their accessibility within the broader research community. Notable exceptions exist, […]


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In operando cryo-STEM of pulse-induced charge density wave switching in TaS$_2$

Kavli Affiliate: Lena F. Kourkoutis | First 5 Authors: James L Hart, Saif Siddique, Noah Schnitzer, Stephen D. Funni, Lena F. Kourkoutis | Summary: The charge density wave (CDW) material 1T-TaS$_2$ exhibits a pulse-induced insulator-to-metal transition, which shows promise for next-generation electronics such as memristive memory and neuromorphic hardware. However, the rational design of TaS$_2$ […]


Continue.. In operando cryo-STEM of pulse-induced charge density wave switching in TaS$_2$