dbos – Page 6 – Kavli Institute Pre-Print Publications

Distinct laminar origins of high-gamma and low-frequency ECoG signals revealed by optogenetics

Posted by dbos October 3, 2025October 13, 2025UCSF

Kavli Affiliate: Kristofer Bouchard | Authors: Pierre-Marie Garderes, Daniel E. Feldman and Kristofer E. Bouchard | Summary: Electrocorticography (ECoG) provides a high-spatiotemporal-resolution measure of cortical activity (cortical surface electrical potentials, CSEPs) in humans and animals. The CSEP high-gamma band (Hγ, 65–170 Hz) correlates with neuronal firing rates at the columnar spatial scale and is widely […]

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Transfer of graded information through gated receptivity to widely broadcast signals

Posted by dbos October 2, 2025October 13, 2025Columbia

Kavli Affiliate: Michael Shadlen | Authors: Lindsey S Brown, NaYoung So, L F Abbott, Michael N Shadlen and Mark S Goldman | Summary: Making accurate decisions requires the brain to maintain evolving representations of accumulated evidence. The population that maintains this evolving representation may change over the course of evidence accumulation. For example, intervening actions […]

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Cerebellar outputs for rapid directional refinement of forelimb movement

Posted by dbos October 2, 2025October 13, 2025UCSD / Salk

Kavli Affiliate: Eiman Azim | Authors: Ayesha R. Thanawalla, Oren Wilcox, Eliza Rhee, Juan Jiang, Kee Wui Huang, Raihana Yusufi, Dalia Saklaway, Akira Nagamori, James M. Conner, Albert I. Chen and Eiman Azim | Summary: Much of our interaction with the world relies on the ability to move our limbs with speed and precision. The […]

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NOVA: a novel R-package enabling multi-parameter analysis and visualization of neural activity in MEA recordings

Posted by dbos October 2, 2025October 13, 2025UCSF

Kavli Affiliate: Anna Molofsky | Authors: Caroline C Escoubas, Ekin Guney, Alex Tudoras Miravet, Nathan Magee, Ronald Phua, Davide Ruggero, Anna V Molofsky and William A Weiss | Summary: Multielectrode array (MEA) technology enables simultaneous recording of electrical signals from neuronal networks, producing complex datasets. Current analytical approaches typically examine a limited number of metrics […]

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Phosphatidylserine and RhoB connect phosphatidylinositol 4-phosphate and phosphatidic acid metabolism at the plasma membrane

Posted by dbos October 2, 2025October 13, 2025Hopkins

Kavli Affiliate: Jin Kang | Authors: Shiying Huang, Yeun Ju Kim, Xiaofu Cao, Timothy W Bumpus, Mira Sohn, Matthew Tyler Menold, Ryan S Dale, Jin Joo Kang, Saori Uematsu, Shagun Gupta, Shu-Bing Qian, Haiyuan Yu, Tamas Balla and Jeremy M Baskin | Summary: Cells tightly control the homeostatic levels and subcellular localizations of membrane phospholipids […]

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The effect of Sinorhizobium meliloti volatilomes and synthetic long-chain methylketones on soil and Medicago truncatula microbiomes

Posted by dbos October 1, 2025October 13, 2025UCSD / Salk

Kavli Affiliate: Rafael Nunez | Authors: Pieter van Dillewijn, Lydia M. Bernabéu-Roda, Virginia Cuéllar, Rafael Núñez, Otto Geiger, Isabel M. López-Lara and María J. Soto | Summary: Bacterial volatile compounds play important roles in intra- and interkingdom interactions but very little is known about their effects on soil and plant microbiomes. The legume symbiont Sinorhizobium […]

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Flexible gaze reinstatement during working memory for natural scenes

Posted by dbos October 1, 2025October 13, 2025UCSD / Salk

Kavli Affiliate: Anastasia Kiyonaga | Authors: Yueying Dong, Yunchen Hung, Lana Gaspariani and Anastasia Kiyonaga | Summary: Working memory (WM) representations may be more action-oriented and anatomically widespread than previously assumed. For instance, oculomotor signatures like gaze biases can reflect spatial WM content. However, the specificity and functional relevance of such signatures is unclear. Here, […]

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Reward-reset interval timing drives patch foraging decisions through neural state transitions in dorsomedial striatum

Posted by dbos October 1, 2025October 13, 2025Hopkins

Kavli Affiliate: Marshall Hussain Shuler | Authors: Elissa Sutlief, Shichen Zhang, Kate Forsberg, Rie Kaneko and Marshall G Hussain Shuler | Summary: Activities with diminishing returns pose a unique computational problem for the brain, requiring a combination of outcome evaluation and temporal tracking. Deciding the right time to stop one pursuit and move to alternatives […]

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From Maps to Models: A Survey on the Reliability of Small Studies of Task-Based fMRI

Posted by dbos October 1, 2025October 13, 2025Hopkins

Kavli Affiliate: Martin Lindquist | Authors: Patrick Sadil and Martin A. Lindquist | Summary: Task-based functional magnetic resonance imaging (fMRI) is a powerful tool for studying brain function. However, the reliability and viability of small-sample studies remain a concern. While it is well understood that larger samples are preferable, researchers often need to interpret findings […]

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Multiscale Hyperbolic Embedding for Cell Hierarchies in Large-Scale Bioinformatics Data

Posted by dbos October 1, 2025October 13, 2025UCSD / Salk

Kavli Affiliate: Tatyana Sharpee | Authors: Mingchen Yao, Anoop Praturu and Tatyana Sharpee | Summary: The increasing size of datasets poses challenges for their visualization and interpretation, highlighting the need for scalable and effective analysis methods. Hyperbolic embedding have shown strong potential in capturing complex hierarchical structures across diverse systems. However, existing hyperbolic embedding methods […]

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