An evolutionarily conserved role for separase in the regulation of nuclear lamins

Posted by dbos Columbia

Kavli Affiliate: Michael Goldberg | Authors: Francesca Cipressa, Gaelle Pennarun, Giuseppe Bosso, Serena Rosignoli, Liliana Tullo, Nadia Schiralli, Chiara Borghi, Alessandro Paiardini, Michael L Goldberg, Pascale Bertrand and Giovanni Cenci | Summary: Separase is a well conserved endopeptidase that facilitates sister chromatid separation at the metaphase-anaphase transition by cleaving cohesins. Beyond its role in chromosome […]


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Solving quadratic binary optimization problems using quantum SDP methods: Non-asymptotic running time analysis

Posted by dbos UCSB

Kavli Affiliate: David Gross | First 5 Authors: Fabian Henze, Viet Tran, Birte Ostermann, Richard Kueng, Timo de Wolff | Summary: Quantum computers can solve semidefinite programs (SDPs) using resources that scale better than state-of-the-art classical methods as a function of the problem dimension. At the same time, the known quantum algorithms scale very unfavorably […]


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From Documents to Dialogue: Building KG-RAG Enhanced AI Assistants

Posted by dbos Cornell

Kavli Affiliate: Dan Luo | First 5 Authors: Manisha Mukherjee, Sungchul Kim, Xiang Chen, Dan Luo, Tong Yu | Summary: The Adobe Experience Platform AI Assistant is a conversational tool that enables organizations to interact seamlessly with proprietary enterprise data through a chatbot. However, due to access restrictions, Large Language Models (LLMs) cannot retrieve these […]


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Human precentral gyrus neurons link speech sequences from listening to speaking

Posted by dbos UCSF

Kavli Affiliate: Edward Chang | Authors: Duo Xu, Jason E Chung, Alexander B Silva, Quinn R Greicius, Sean L Metzger, Yizhen Zhang, Matthew K Leonard, Manish K Aghi, Shawn L Hervey-Jumper and Edward F Chang | Summary: Speech perception and production are interconnected processes, but the underlying neural mechanisms remain unclear. We investigated this relationship […]


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The GammaTPC Gamma-Ray Telescope Concept

Posted by dbos Stanford

Kavli Affiliate: Eric Charles | First 5 Authors: Tom Shutt, Bahrudin Trbalic, Eric Charles, Niccolo Di Lalla, Oliver Hitchcock | Summary: We present GammaTPC, a transformative 0.1-10 MeV $gamma$-ray instrument concept featuring a tracker using a liquid argon time projection chamber (LAr TPC) technology with the novel GAMPix high spatial resolution and ultra low power […]


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RelaCtrl: Relevance-Guided Efficient Control for Diffusion Transformers

Posted by dbos Peking

Kavli Affiliate: Jing Wang | First 5 Authors: Ke Cao, Jing Wang, Ao Ma, Jiasong Feng, Zhanjie Zhang | Summary: The Diffusion Transformer plays a pivotal role in advancing text-to-image and text-to-video generation, owing primarily to its inherent scalability. However, existing controlled diffusion transformer methods incur significant parameter and computational overheads and suffer from inefficient […]


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Neuromodulation in neural organoids with shell MEAs

Posted by dbos Hopkins

Kavli Affiliate: Brian Caffo | Authors: Chris Acha, Derosh George, Lauren C. Diaz, Ziwei Ouyang, Dowlette-Mary M. Alam El Din, Hrishikesh Surlekar, Babak Moghadas, Pratyush Sai R. Rayasam, Yu-Chiao Lai, Lena Smirnova, Brian S. Caffo, Erik C. Johnson and David H. Gracias | Summary: Neural organoids (NOs) have emerged as important tissue engineering models for […]


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One-loop Renormalization of BPS String Masses in Pseudo-anomalous Heterotic String

Posted by dbos Chicago

Kavli Affiliate: Jeffrey A. Harvey | First 5 Authors: Jeffrey A. Harvey, Tai Wai Hu, , , | Summary: Compactification of heterotic string on a Calabi-Yau threefold can lead to a four-dimensional low-energy effective theory which contains a $U(1)$ gauge theory which is pseudo-anomalous, meaning that the fermion content is anomalous, but that the fermion […]


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Orbital Wigner functions and quantum transport in multiband systems

Posted by dbos Berkeley

Kavli Affiliate: Joel E. Moore | First 5 Authors: Johannes Mitscherling, Dan S. Borgnia, SuryaNeil Ahuja, Joel E. Moore, Vir B. Bulchandani | Summary: Traditional theories of electron transport in crystals are based on the Boltzmann equation and do not capture physics arising from quantum coherence. We introduce a transport formalism based on ”orbital Wigner […]


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Characterization of a TES-based Anti-Coincidence Detector for Future Large Field-of-View X-ray Calorimetry Missions

Posted by dbos Stanford

Kavli Affiliate: Noah Kurinsky | First 5 Authors: Samuel V. Hull, Joseph S. Adams, Simon R. Bandler, Matthew Cherry, James A. Chervenak | Summary: Microcalorimeter instruments aboard future X-ray observatories will require an anti-coincidence (anti-co) detector to veto charged particle events and reduce the non-X-ray background. We have developed a large-format, TES-based prototype anti-coincidence detector […]


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