Kavli Affiliate: Justus M Kebschull | Authors: Hyopil Kim, Huihui Qi, Craig Washington, Xiaoping Liang and Justus M Kebschull | Summary: The barcoded connectomics tool MAPseq enables highly multiplexed projection mapping of individual neurons by translating neuroanatomy into a DNA sequencing problem. Here we present MAPseq2, a user-friendly protocol with 3-4 fold increased barcode detection […]
Kavli Affiliate: Elena Gracheva | Authors: Tingting Gu, Elena Gracheva, Michael Lee, Wilson M Leung, Sophia Bieser, Alixandria Nielsen, Adam T. Smiley, Nhi N.T. Vuong, Matthias Walther, Gunter Reuter, Sarah C.R. Elgin and Andrew M Arsham | Summary: Eukaryotic genomes are packaged into chromatin, a regulatory nucleoprotein assembly. Establishment, maintenance, and interconversion of chromatin states […]
Kavli Affiliate: Liam Paninski and Darcy Peterka | Authors: Marcus A Triplett, Edgar Bäumler, Alex Prodan, Rokas Stonis, Darcy S Peterka, Michael Häusser and Liam Paninski | Summary: Determining the intricate structure and function of neural circuits requires the ability to precisely manipulate circuit activity. Two-photon holographic optogenetics has emerged as a powerful tool for […]
Kavli Affiliate: Marcelo Mattar | Authors: Hua-Dong Xiong, Li Ji-An, Robert C Wilson and Marcelo G Mattar | Summary: A hallmark of intelligence is the ability to adapt behavior to changing environments, which requires adapting one’s own learning strategies. This phenomenon is known as learning to learn in cognitive science and meta-learning in artificial intelligence. […]
Kavli Affiliate: Timothy Brown | Authors: Abhi Aggarwal, Heather A. Baker, Celine D. Durst, I-Wen Chen, Pablo de Chambrier, Julia Marie Gonzales, Jonathan S. Marvin, Milene Vandal, Torgny Lundberg, Kenryo Sakoi, Ronak H Patel, Ching-Yao Wang, Frank Visser, Yannick Fouad, Smrithi Sunil, Matthew Wiens, Takuya Terai, Kei Takahashi-Yamashiro, Roger J. Thompson, Timothy A. Brown, Yusuke […]
Kavli Affiliate: Seth Blackshaw | Authors: Parris Washington Chandler, Sang Soo Lee, Leighton Duncan, Dong Won Thomas Kim, Mark Wu and Seth Blackshaw | Summary: Sleep pressure, the accumulating drive towards sleep during wakefulness, is shaped by Lhx6-positive GABAergic neurons in the zona incerta (ZI). Here, we show that these neurons are broadly activated both […]
Kavli Affiliate: V. S. Ramachandran | Authors: Devica Ranade, Priti Bangal, Bhoj Kumar Acharya, Peroth Balakrishnan, Sahas Barve, Malyasri Bhattacharya, Aparajita Datta, Mousumi Ghosh-Harihar, Govindan Veeraswami Gopi, Farah Ishtiaq, Soumya Iyengar, Manjari Jain, Girish Jathar, Rajah Jayapal, Panchapakesan Jeganathan, Ashish Jha, Monica Kaushik, Anil Kumar, Raman Kumar, Suresh Kumar, Gopinathan Maheswaran, Shirish S. Manchi, Prachi […]
Kavli Affiliate: Vincent Ferrera | Authors: Dong Liu, Xingfeng Shao, Fabian A Munoz Silva, Soroosh Sanatkhani, Ray Lee, Elisa Konofagou, Danny JJ Wang and Vincent P Ferrera | Summary: This study applied diffusion-prepared pseudo-continuous arterial spin labeling (DP-pCASL) to quantify cerebral blood flow (CBF), arterial transit time (ATT), and blood-brain barrier (BBB) water exchange rate […]
Kavli Affiliate: Michael Miller | Authors: Niklas Krick, Jacob Davies, Bramwell Coulson, Daniel Sobrido-Camean, Michael Miller, Matthew C.W. Oswald, Aref Arzan Zarin, Richard Baines and Matthias Landgraf | Summary: As developing neural circuits become functional, they undergo a phase of heightened plasticity that facilitates network tuning in response to intrinsic and/or extrinsic stimuli. These developmental […]
Kavli Affiliate: Robert Edwards | Authors: Susanna R Grigson, George Bouras, Bhavya Papudeshi, Vijini Mallawaarachchi, Michael J Roach, Przemyslaw Decewicz and Robert A Edwards | Summary: Sensorimotor and cognitive abilities undergo substantial changes throughout the human lifespan, but the corresponding changes in the functional properties of cortical networks remain poorly understood. This can be studied […]