Versatile high-speed volumetric imaging from microscopic to macroscopic scale by self-adaptive oblique plane microscopy

Kavli Affiliate: Dwight Bergles | Authors: Dominique Meyer, Grant Kroeschell, Xiankun Lu, Linh Hoang, Haochen Wang, Shuying Li, Yu Kang T Xu, Lei Tan, Jeff S Mumm, Dwight E Bergles and Ji Yi | Summary: There is an increasing need for large-scale high-speed volumetric recording in complex multi-cellular model systems to define dynamic processes. Oblique […]


Continue.. Versatile high-speed volumetric imaging from microscopic to macroscopic scale by self-adaptive oblique plane microscopy

Emergent Elasticity and Quasiconformal Flow in Active Solids

Kavli Affiliate: Boris I. Shraiman | Summary:A constitutive relation between stress and strain relative to a reference state is the basic assumption of elasticity theory. However, in living matter, force generation is governed by motor molecule activity, which does not depend on deformation relative to a reference. A different approach is needed to describe how […]


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Elasticity without a reference state: continuum mechanics of active tension nets

Kavli Affiliate: Boris I. Shraiman | Summary:A constitutive relation between stress and strain relative to a reference state is the basic assumption of elasticity theory. However, in living matter, stress is governed by (motor molecule) activity rather than a constitutive law. What paradigm takes the place of elasticity in this setting? Here, we derive a […]


Continue.. Elasticity without a reference state: continuum mechanics of active tension nets

Transplantation of Human IPSC-derived Microglia Ameliorates Neuropathology and Circuit Dysfunction in Progranulin-Deficient Mice

Kavli Affiliate: Jeanne Paz | Authors: Hayk Davtyan, Sarah Naguib, Yuliya Voskobiynyk, Jean Paul Chadarevian, Joia K. Capocchi, Jeannie L. Giacchino, Ghazaleh Eskandari-Sedighi, Vivianna Denittis, Jeremy Ford, Ani Agababian, Jasmine Nguyen, Alina Chadarevian, Madison Sutherland, Sepideh Kiani Shabestari, Alissa Nanali, Jiasheng Zhang, Salvatore Spina, Man Ying Wong, Lea Tenenholz Grinberg, William W Seeley, Eric Huang, […]


Continue.. Transplantation of Human IPSC-derived Microglia Ameliorates Neuropathology and Circuit Dysfunction in Progranulin-Deficient Mice

Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.

Kavli Affiliate: Seth Blackshaw | Authors: Kurt Weir, Pin Lyu, Sangeetha Kandoi, Roujin An, Nicole Pannullo, Isabella Palazzo, Jared Tangeman, Jun Shi, Steven DeVries, Dana Merriman, Jiang Qian and Seth Blackshaw | Summary: Evolutionary adaptation to diurnal vision in ground squirrels has led to the development of a cone-dominant retina, in stark contrast to the […]


Continue.. Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.

Sox8 and Sox9 regulate differentiation and nuclear positioning of retinal Muller glia.

Kavli Affiliate: Seth Blackshaw | Authors: Nicole Pannullo, Debarpita Datta, Clayton Santiago, Jared Tangeman, Lizhi Jiang, Leighton Duncan and Seth Blackshaw | Summary: Temporal patterning of retinal progenitor cells governs the sequential generation of retinal cell types, with gliogenesis occurring late in development. Sox8 and Sox9, members of the SoxE transcription factor family, are highly […]


Continue.. Sox8 and Sox9 regulate differentiation and nuclear positioning of retinal Muller glia.

Expanding the High-z Supernova Frontier: “Wide-Area” JWST Discoveries from the First Two Years of COSMOS-Web

Kavli Affiliate: Kohei Inayoshi | Summary:Transient astronomy in the early Universe (z > 2) remains largely unexplored, lying beyond the rest-frame optical spectroscopic reach of most current observatories. Yet this regime promises transformative insights, with high-redshift transients providing direct access to the early Universe and enabling studies of how stellar populations and cosmology evolve over […]


Continue.. Expanding the High-z Supernova Frontier: “Wide-Area” JWST Discoveries from the First Two Years of COSMOS-Web

Expanding the High-z Supernova Frontier: “Wide-Area” JWST Discoveries from the First Two Years of COSMOS-Web

Kavli Affiliate: Kohei Inayoshi | Summary:Transient astronomy in the early Universe (z > 2) remains largely unexplored, lying beyond the rest-frame optical spectroscopic reach of most current observatories. Yet this regime promises transformative insights, with high-redshift transients providing direct access to the early Universe and enabling studies of how stellar populations and cosmology evolve over […]


Continue.. Expanding the High-z Supernova Frontier: “Wide-Area” JWST Discoveries from the First Two Years of COSMOS-Web

Towards a Self-Driving Trigger at the LHC: Adaptive Response in Real Time

Kavli Affiliate: David W. Miller | Summary:Real-time data filtering and selection — or trigger — systems at high-throughput scientific facilities such as the experiments at the Large Hadron Collider (LHC) must process extremely high-rate data streams under stringent bandwidth, latency, and storage constraints. Yet these systems are typically designed as static, hand-tuned menus of selection […]


Continue.. Towards a Self-Driving Trigger at the LHC: Adaptive Response in Real Time

Forbidden second harmonics in centrosymmetric bilayer crystals

Kavli Affiliate: Ali Javey | Summary:Optical spectroscopy based on second-order nonlinearity is a critical technique for characterizing two-dimensional (2D) crystals as well as bioimaging and quantum optics. It is generally believed that second-harmonic generation (SHG) in centrosymmetric crystals, such as graphene and other bilayer 2D crystals, is negligible without externally breaking the inversion symmetry. Here, […]


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