Childhood brain tumours instruct cranial haematopoiesis and immunotolerance

Kavli Affiliate: Arnold R. Kriegstein | Authors: Elizabeth Alexandra Cooper, David A Posner, Colin Y. C Lee, Linda Hu, Sigourney Bonner, Jessica T Taylor, Oscar Baldwin, Rocio Jimenez-Guerrero, Katherine E Masih, Katherine Wickham Rahrmann, Jason Eigenbrood, Gina Ngo, Valar Nila Roamio Franklin, Clive D’Santos, Richard Mair, Thomas Santarius, Claudia Craven, Ibrahim Jalloh, Julia Moreno-Vicente, Timotheus […]


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Novel Predictive Spatial Biomarker in Non-Small Cell Lung Carcinoma: The Diversity of Niches Unlocking Treatment Sensitivity (DONUTS)

Kavli Affiliate: Alexander Szalay | Authors: Tricia R Cottrell, Jeffrey S Roskes, Michael Fotheringham, Emily Cohen, Boyang Zhang, Logan L Engle, Daphne Wang, Elizabeth Will, Joel C Sunshine, Daniel Jimenez-Sanchez, Zhen Zheng, Justina X Caushi, Jiajia Zhang, Nina D’Amiano, Julie Stein-Deutsch, Sonali Uttam, Katie Pirie, Darah Vlaminck, Michelle Mataj, Alexa Fiorante, Nicole Espinosa, Teodora Popa, […]


Continue.. Novel Predictive Spatial Biomarker in Non-Small Cell Lung Carcinoma: The Diversity of Niches Unlocking Treatment Sensitivity (DONUTS)

Network-aware self-supervised learning enables high-content phenotypic screening for genetic modifiers of neuronal activity dynamics

Kavli Affiliate: Michael Keiser | Authors: Parker Grosjean, Kaivalya Shevade, Cuong Nguyen, Sarah Ancheta, Karl Mader, Ivan Franco, Seok-Jin Heo, Greyson Lewis, Steven Boggess, Angelique De Domenico, Erik Ullian, Shawn Shafer, Adam Litterman, Laralynne Przybyla, Michael J Keiser, Jamie Ifkovits, Adam Yala and Martin Kampmann | Summary: High-throughput phenotypic screening has historically relied on manually […]


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A nearly pristine star from the Large Magellanic Cloud

Kavli Affiliate: Alexander P. Ji | First 5 Authors: Alexander P. Ji, Alexander P. Ji, , , | Summary: The first stars formed out of pristine gas, causing them to be so massive that none are expected to have survived until today. If their direct descendants were sufficiently low-mass stars, they could exist today and […]


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BlackTHUNDER: evidence for three massive black holes in a z~5 galaxy

Kavli Affiliate: Debora Sijacki | First 5 Authors: Hannah Übler, Hannah Übler, , , | Summary: We present observational evidence for three massive, accreting black holes in the $z=5.0167$ galaxy J0148-4214 from JWST/NIRSpec-IFU spectroscopy. The black holes are revealed through broad H$alpha$ emission (FWHM = 430-2920 km/s) without a forbidden-line counterpart in the bright [O […]


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Spatiomolecular mapping reveals anatomical organization of heterogeneous cell types in the human nucleus accumbens

Kavli Affiliate: Keri Martinowich | Authors: Prashanthi Ravichandran, Svitlana V. Bach, Robert A. Phillips III, Madeline R. Valentine, Nicholas J. Eagles, Yufeng Du, Ishbel Del Rosario, Ryan A. Miller, Heena R. Divecha, Madhavi Tippani, Kelsey D. Montgomery, Joel E. Kleinman, Shizhong Han, Stephanie Cerceo Page III, Thomas M. Hyde, Leonardo Collado Torres, Alexis Battle, Keri […]


Continue.. Spatiomolecular mapping reveals anatomical organization of heterogeneous cell types in the human nucleus accumbens

MMR1: Enhancing Multimodal Reasoning with Variance-Aware Sampling and Open Resources

Kavli Affiliate: Jing Wang | First 5 Authors: Sicong Leng, Sicong Leng, , , | Summary: Large multimodal reasoning models have achieved rapid progress, but their advancement is constrained by two major limitations: the absence of open, large-scale, high-quality long chain-of-thought (CoT) data, and the instability of reinforcement learning (RL) algorithms in post-training. Group Relative […]


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RollPacker: Mitigating Long-Tail Rollouts for Fast, Synchronous RL Post-Training

Kavli Affiliate: Wei Gao | First 5 Authors: Wei Gao, Wei Gao, , , | Summary: Reinforcement Learning (RL) is a pivotal post-training technique for enhancing the reasoning capabilities of Large Language Models (LLMs). However, synchronous RL post-training often suffers from significant GPU underutilization, referred to as bubbles, caused by imbalanced response lengths within rollout […]


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Tracking spin qubit frequency variations over 912 days

Kavli Affiliate: Giordano Scappucci | First 5 Authors: Kenji Capannelli, Kenji Capannelli, , , | Summary: Solid-state qubits are sensitive to their microscopic environment, causing the qubit properties to fluctuate on a wide range of timescales. The sub-Hz end of the spectrum is usually dealt with by repeated background calibrations, which bring considerable overhead. It […]


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Quantum Path Control in High-Order Harmonic Generation via Squeezed Lights

Kavli Affiliate: Feng Wang | First 5 Authors: Feng Wang, Feng Wang, , , | Summary: High-order harmonic generation (HHG), a robust tabletop source for producing attosecond pulses, has been extensively utilized in attosecond metrology. Traditionally, HHG driven by classical laser fields involves two typical quantum paths (short and long quantum paths) contributing to harmonic […]


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