Neuronal Silencing and Protection in a Mouse Model of Demyelination

Kavli Affiliate: Aniruddha Das | Authors: Aniruddha Das, Julie Borovicka, Hale Tobin, Shruti Bhatia, Jacob Icardi, Ghazaal Tahmasebi, Priyanka Agochiya, Shriya Singh, Bruce Trapp and Hod Dana | Summary: Damage to the myelin sheath that protects axons in the central nervous system is a hallmark pathology of demyelinating diseases like multiple sclerosis. Cuprizone-induced demyelination in […]


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Population-level morphological analysis of paired CO2- and odor-sensing olfactory neurons in D. melanogaster via volume electron microscopy

Kavli Affiliate: Kathleen Cullen and Vikram Chib | Authors: Jonathan Choy, Shadi Charara, Kalyani Cauwenberghs, Quintyn McKaughan, Keun-Young Kim, Mark Ellisman and Chih-Ying Su | Summary: Dendritic morphology is a defining characteristic of neuronal subtypes. In Drosophila, heterotypic olfactory receptor neurons (ORNs) expressing different receptors display diverse dendritic morphologies, but whether such diversity exists among […]


Continue.. Population-level morphological analysis of paired CO2- and odor-sensing olfactory neurons in D. melanogaster via volume electron microscopy

Network Biomarkers of Alzheimer’s Disease Risk Derived from Joint Volume and Texture Covariance Patterns in Mouse Models

Kavli Affiliate: Joshua Vogelstein | Authors: Eric W Bridgeford, Jaewon Chung, Robert J Anderson, Ali Mahzarnia, Jacques A Stout, Hae Sol Moon, Zay Yar Han, Joshua T Vogelstein and Alexandra Badea | Summary: Alzheimer’s disease (AD) lacks effective cures and is typically detected after substantial pathological changes have occurred, making intervention challenging. Early detection and […]


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A Generalist Intracortical Motor Decoder

Kavli Affiliate: Kristofer Bouchard | Authors: Joel Ye, Fabio Rizzoglio, Adam Smoulder, Hongwei Mao, Xuan Ma, Patrick Marino, Raeed H Chowdhury, Dalton D Moore, Gary Blumenthal, Will Hockeimer, Nicolas G. Kunigk, J Patrick Mayo, Aaron P Batista, Steven M Chase, Adam G Rouse, Michael L. Boninger, Charles Greenspon, Andrew B. Schwartz, Nicholas Hatsopoulos, Lee E […]


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Momentum and Matter Matter for Axion Dark Matter Matters on Earth

Kavli Affiliate: Yevgeny V. Stadnik | First 5 Authors: Abhishek Banerjee, Itay M. Bloch, Quentin Bonnefoy, Sebastian A. R. Ellis, Gilad Perez | Summary: We investigate the implications of matter effects to searches for axion Dark Matter on Earth. The finite momentum of axion Dark Matter is crucial to elucidating the effects of Earth on […]


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CMB-S4: Foreground-Cleaning Pipeline Comparison for Measuring Primordial Gravitational Waves

Kavli Affiliate: Zeeshan Ahmed | First 5 Authors: Federico Bianchini, Dominic Beck, W. L. Kimmy Wu, Zeeshan Ahmed, Sebastian Belkner | Summary: We compare multiple foreground-cleaning pipelines for estimating the tensor-to-scalar ratio, $r$, using simulated maps of the planned CMB-S4 experiment within the context of the South Pole Deep Patch. To evaluate robustness, we analyze […]


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Beyond Prompt Content: Enhancing LLM Performance via Content-Format Integrated Prompt Optimization

Kavli Affiliate: Cheng Peng | First 5 Authors: Yuanye Liu, Jiahang Xu, Li Lyna Zhang, Qi Chen, Xuan Feng | Summary: Large Language Models (LLMs) have shown significant capability across various tasks, with their real-world effectiveness often driven by prompt design. While recent research has focused on optimizing prompt content, the role of prompt formatting, […]


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Content-Rich AIGC Video Quality Assessment via Intricate Text Alignment and Motion-Aware Consistency

Kavli Affiliate: Wei Gao | First 5 Authors: Shangkun Sun, Xiaoyu Liang, Bowen Qu, Wei Gao, | Summary: The advent of next-generation video generation models like textit{Sora} poses challenges for AI-generated content (AIGC) video quality assessment (VQA). These models substantially mitigate flickering artifacts prevalent in prior models, enable longer and complex text prompts and generate […]


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Scaling Laws in Patchification: An Image Is Worth 50,176 Tokens And More

Kavli Affiliate: Feng Wang | First 5 Authors: Feng Wang, Yaodong Yu, Guoyizhe Wei, Wei Shao, Yuyin Zhou | Summary: Since the introduction of Vision Transformer (ViT), patchification has long been regarded as a de facto image tokenization approach for plain visual architectures. By compressing the spatial size of images, this approach can effectively shorten […]


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Ruling out AGNs as the dominant source of cosmic reionization with JWST

Kavli Affiliate: Linhua Jiang | First 5 Authors: Danyang Jiang, Linhua Jiang, Shengxiu Sun, Weiyang Liu, Shuqi Fu | Summary: Cosmic reionization represents the latest phase transition of the intergalactic medium (IGM) in the Universe. It has long been debated whether galaxies or active galactic nuclei (AGNs) are the major source of Lyman continuum (LyC) […]


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