Design and Validation of a Cold Load for Characterization of CMB-S4 Detectors

Kavli Affiliate: Bradford A. Benson | First 5 Authors: Cesiley L. King, Ian Gullet, Adam J. Anderson, Bradford A. Benson, Rick Bihary | Summary: We present the design and validation of a variable temperature cryogenic blackbody source, hereinafter called a cold load, that will be used to characterize detectors to be deployed by CMB-S4, the […]


Continue.. Design and Validation of a Cold Load for Characterization of CMB-S4 Detectors

Design and Validation of a Cold Load for Characterization of CMB-S4 Detectors

Kavli Affiliate: Bradford A. Benson | First 5 Authors: Cesiley L. King, Ian Gullet, Adam J. Anderson, Bradford A. Benson, Rick Bihary | Summary: We present the design and validation of a variable temperature cryogenic blackbody source, hereinafter called a cold load, that will be used to characterize detectors to be deployed by CMB-S4, the […]


Continue.. Design and Validation of a Cold Load for Characterization of CMB-S4 Detectors

Design and Validation of a Cold Load for Characterization of CMB-S4 Detectors

Kavli Affiliate: Bradford A. Benson | First 5 Authors: Cesiley L. King, Ian Gullet, Adam J. Anderson, Bradford A. Benson, Rick Bihary | Summary: We present the design and validation of a variable temperature cryogenic blackbody source, hereinafter called a cold load, that will be used to characterize detectors to be deployed by CMB-S4, the […]


Continue.. Design and Validation of a Cold Load for Characterization of CMB-S4 Detectors

Prior-Informed AGN-Host Spectral Decomposition Using PyQSOFit

Kavli Affiliate: John D. Silverman | First 5 Authors: Wenke Ren, Hengxiao Guo, Yue Shen, John D. Silverman, Colin J. Burke | Summary: We introduce an improved method for decomposing the emission of active galactic nuclei (AGN) and their host galaxies using templates from principal component analysis (PCA). This approach integrates prior information from PCA […]


Continue.. Prior-Informed AGN-Host Spectral Decomposition Using PyQSOFit

Prior-Informed AGN-Host Spectral Decomposition Using PyQSOFit

Kavli Affiliate: John D. Silverman | First 5 Authors: Wenke Ren, Hengxiao Guo, Yue Shen, John D. Silverman, Colin J. Burke | Summary: We introduce an improved method for decomposing the emission of active galactic nuclei (AGN) and their host galaxies using templates from principal component analysis (PCA). This approach integrates prior information from PCA […]


Continue.. Prior-Informed AGN-Host Spectral Decomposition Using PyQSOFit

Gravitational waves from mergers of Population III binary black holes: roles played by two evolution channels

Kavli Affiliate: George Efstathiou | First 5 Authors: Boyuan Liu, Tilman Hartwig, Nina S. Sartorio, Irina Dvorkin, Guglielmo Costa | Summary: The gravitational wave (GW) signal from binary black hole (BBH) mergers is a promising probe of Population III (Pop III) stars. To fully unleash the power of the GW probe, one important step is […]


Continue.. Gravitational waves from mergers of Population III binary black holes: roles played by two evolution channels

Gravitational waves from mergers of Population III binary black holes: roles played by two evolution channels

Kavli Affiliate: George Efstathiou | First 5 Authors: Boyuan Liu, Tilman Hartwig, Nina S. Sartorio, Irina Dvorkin, Guglielmo Costa | Summary: The gravitational wave (GW) signal from binary black hole (BBH) mergers is a promising probe of Population III (Pop III) stars. To fully unleash the power of the GW probe, one important step is […]


Continue.. Gravitational waves from mergers of Population III binary black holes: roles played by two evolution channels

Suppression of astrocyte BMP signaling improves fragile X syndrome molecular signatures and functional deficits

Kavli Affiliate: Nicola Allen | Authors: James Deng, Lara Labarta-Bajo, Ashley N Brandebura, Samuel B Kahn, Antonio F M Pinto, Jolene K Diedrich and Nicola J Allen | Summary: Fragile X syndrome (FXS) is a monogenic neurodevelopmental disorder with manifestations spanning molecular, neuroanatomical, and behavioral changes. Astrocytes contribute to FXS pathogenesis and show hundreds of […]


Continue.. Suppression of astrocyte BMP signaling improves fragile X syndrome molecular signatures and functional deficits

Structure of the E3 ligase CRL2-ZYG11B with substrates reveals the molecular basis for N-degron recognition and ubiquitination

Kavli Affiliate: Yifan Cheng | Authors: Xi Liu, Yang Li, Lennice Castro, Zanlin Yu, Yifan Cheng, Matthew D Daugherty and John D Gross | Summary: ZYG11B is a substrate specificity factor for Cullin-RING ubiquitin ligase (CRL2) involved in many biological processes, including Gly/N-degron pathways. Yet how the binding of ZYG11B with CRL2 is coupled to […]


Continue.. Structure of the E3 ligase CRL2-ZYG11B with substrates reveals the molecular basis for N-degron recognition and ubiquitination

Nonlinear compliance of NompC gating spring and its implication in mechanotransduction

Kavli Affiliate: Yuh Nung and Jan Yifan Cheng and Yuh Nung Jan | Authors: Yukun Wang, Peng Jin, Avinash Kumar, Lily Jan, Yifan Cheng, Yuh-Nung Jan and Yongli Zhang | Summary: TCytoskeleton-tethered mechanosensitive channels (MSCs) utilize compliant proteins or protein domains called gating springs to convert mechanical stimuli into electric signals, enabling sound and touch […]


Continue.. Nonlinear compliance of NompC gating spring and its implication in mechanotransduction