In situ architecture of the lipid transport protein VPS13C at ER-lysosomes membrane contacts

Kavli Affiliate: Pietro DeCamilli | Authors: Shujun Cai, Yumei Wu, Andres Guillen-Samander, William F Hancock-Cerutti, Jun Liu and Pietro De Camilli | Summary: VPS13 is a eukaryotic lipid transport protein localized at membrane contact sites. Previous studies suggested that it may transfer lipids between adjacent bilayers by a bridge-like mechanism. Direct evidence for this hypothesis […]


Continue.. In situ architecture of the lipid transport protein VPS13C at ER-lysosomes membrane contacts

GaitStrip: Gait Recognition via Effective Strip-based Feature Representations and Multi-Level Framework

Kavli Affiliate: Zheng Zhu | First 5 Authors: Ming Wang, Beibei Lin, Xianda Guo, Lincheng Li, Zheng Zhu | Summary: Many gait recognition methods first partition the human gait into N-parts and then combine them to establish part-based feature representations. Their gait recognition performance is often affected by partitioning strategies, which are empirically chosen in […]


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Physics Opportunities for the Fermilab Booster Replacement

Kavli Affiliate: Gordan Krnjaic | First 5 Authors: John Arrington, Joshua Barrow, Brian Batell, Robert Bernstein, Nikita Blinov | Summary: This white paper presents opportunities afforded by the Fermilab Booster Replacement and its various options. Its goal is to inform the design process of the Booster Replacement about the accelerator needs of the various options, […]


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Probing squeezing for gravitational-wave detectors with an audio-band field

Kavli Affiliate: Lisa Barsotti | First 5 Authors: Dhruva Ganapathy, Victoria Xu, Wenxuan Jia, Chris Whittle, Maggie Tse | Summary: Squeezed vacuum states are now employed in gravitational-wave interferometric detectors, enhancing their sensitivity and thus enabling richer astrophysical observations. In future observing runs, the detectors will incorporate a filter cavity to suppress quantum radiation pressure […]


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Towards performant and reliable undersampled MR reconstruction via diffusion model sampling

Kavli Affiliate: Cheng Peng | First 5 Authors: Cheng Peng, Pengfei Guo, S. Kevin Zhou, Vishal Patel, Rama Chellappa | Summary: Magnetic Resonance (MR) image reconstruction from under-sampled acquisition promises faster scanning time. To this end, current State-of-The-Art (SoTA) approaches leverage deep neural networks and supervised training to learn a recovery model. While these approaches […]


Continue.. Towards performant and reliable undersampled MR reconstruction via diffusion model sampling

Mid-Air Helicopter Delivery at Mars Using a Jetpack

Kavli Affiliate: Morteza Gharib | First 5 Authors: Jeff Delaune, Jacob Izraelevitz, Samuel Sirlin, David Sternberg, Louis Giersch | Summary: Mid-Air Helicopter Delivery (MAHD) is a new Entry, Descent and Landing (EDL) architecture to enable in situ mobility for Mars science at lower cost than previous missions. It uses a jetpack to slow down a […]


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Enzyme-Responsive Nanoparticles for the Targeted Delivery of an MMP Inhibitor to the Heart post Myocardial Infarction

Kavli Affiliate: Karen Christman | Authors: Holly Sullivan, Yifei Liang, Kendra Worthington, Colin Luo, Nathan C Gianneschi and Karen Christman | Summary: In this paper, we describe block copolymer amphiphiles consisting of a hydrophilic matrix metalloproteinase (MMP) peptide substrate, and a hydrophobic small molecule MMP inhibitor PD166793 for the treatment of acute myocardial infarction. These […]


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Undersampled MRI Reconstruction with Side Information-Guided Normalisation

Kavli Affiliate: Jing Wang | First 5 Authors: Xinwen Liu, Jing Wang, Cheng Peng, Shekhar S. Chandra, Feng Liu | Summary: Magnetic resonance (MR) images exhibit various contrasts and appearances based on factors such as different acquisition protocols, views, manufacturers, scanning parameters, etc. This generally accessible appearance-related side information affects deep learning-based undersampled magnetic resonance […]


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Uncovering the true periods of the young sub-Neptunes orbiting TOI-2076

Kavli Affiliate: Avi Shporer | First 5 Authors: Hugh P. Osborn, Andrea Bonfanti, Davide Gandolfi, Christina Hedges, Adrien Leleu | Summary: Context: TOI-2076 is a transiting three-planet system of sub-Neptunes orbiting a bright (G = 8.9 mag), young ($340pm80$ Myr) K-type star. Although a validated planetary system, the orbits of the two outer planets were […]


Continue.. Uncovering the true periods of the young sub-Neptunes orbiting TOI-2076