Kavli Affiliate: Menno Witter, Asgeir Kobro-Flatmoen | Authors: Katrine Sjaastad Hanssen, Menno P. Witter, Axel Sandvig, Ioanna Sandvig and Asgeir Kobro-Flatmoen | Summary: Abstract Background Primary neuronal cultures enable cell-biological studies of Alzheimer’s disease (AD), albeit typically non-neuron-specific. The first cortical neurons affected in AD reside in layer II of the lateralmost part of the […]
Continue.. Microdissection and culturing of adult lateral entorhinal cortex layer II neurons from APP/PS1 Alzheimer model mice