Multiplexed and scalable cellular phenotyping toward the standardized three-dimensional human neuroanatomy

Kavli Affiliate: Nathaniel Heintz | Authors: Tatsuya C. Murakami and Nathaniel Heintz | Summary: Abstract The advent of three-dimensional histological methods has advanced studies of cellular-resolution anatomy of the brain. The use of whole-mount staining and tissue clearing has advanced systems-level identification of cells underlying brain functions in mouse models. However, application of these methods […]


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Copiotrophs dominate rhizosphere microbiomes and growth rate potential is a major factor explaining the rhizosphere effect

Kavli Affiliate: Jose Suarez Lopez | Authors: José Luis López, Nikolaos Pappas, Sanne WM Poppeliers, Juan J. Sanchez-Gil, Arista Fourie-Fouche, Ronnie de Jonge and Bas E. Dutilh | Summary: Abstract The structure and function of the root microbial community is shaped by plant root activity, enriching specific microbial taxa and functions from the surrounding soil […]


Continue.. Copiotrophs dominate rhizosphere microbiomes and growth rate potential is a major factor explaining the rhizosphere effect

Multiplexed selectivity screening of anti-GPCR antibodies

Kavli Affiliate: Thomas P. Sakmar | Authors: Leo Dahl, Ilana Kotliar, Annika Bendes, Tea Dodig-Crnkovic, Samuel Fromm, Arne Elofsson, Mathias Uhlen, Thomas P Sakmar and Jochen Schwenk | Summary: Abstract G protein-coupled receptors (GPCRs) control critical cellular signaling pathways. Therapeutic agents, such as antibodies (Abs), are being developed to modulate GPCR signaling pathways. However, validating […]


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Inferring Maps of the Sun’s Far-side Unsigned Magnetic Flux from Far-side Helioseismic Images using Machine Learning Techniques

Kavli Affiliate: J. Todd Hoeksema | Summary:Accurate modeling of the Sun’s coronal magnetic field and solar wind structures require inputs of the solar global magnetic field, including both the near and far sides, but the Sun’s far-side magnetic field cannot be directly observed. However, the Sun’s far-side active regions are routinely monitored by helioseismic imaging […]


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Environmental and genetic drivers of population differences in SARS-CoV-2 immune responses

Kavli Affiliate: Jean Laurent Casanova | Authors: Yann Aquino, Aurélie Bisiaux, Zhi Li, Mary O’Neill, Javier Mendoza-Revilla, Sarah Hélène Merkling, Gaspard Kerner, Milena Hasan, Valentina Libri, Vincent Bondet, Nikaïa Smith, Camille de Cevins, Mickaël M Ménager, Francesca Luca, Roger Pique-Regi, Giovanna Barba-Spaeth, Stefano Pietropaoli, Olivier Schwartz, Geert Leroux-Roels, Cheuk-Kwong Lee, Kathy Leung, Joseph T.K. Wu, […]


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Factors governing attachment of Rhizobium leguminosarum to legume roots

Kavli Affiliate: V. S. Ramachandran | Authors: Jack Parsons, Clare Cocker, Alison East, Rachel Wheatley, Vinoy Ramachandran, Farnusch Kaschani, Markus Kaiser and Philip Poole | Summary: Abstract Primary attachment of rhizobia to host legume roots depends on pH and is the first physical interaction during nodulation. Genome-wide insertion sequencing, luminescence-based attachment assays and proteomic analysis […]


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The categorical DT/PT correspondence and quasi-BPS categories for local surfaces

Kavli Affiliate: Yukinobu Toda | Summary:We construct semiorthogonal decompositions of Donaldson-Thomas (DT) categories for reduced curve classes on local surfaces into products of quasi-BPS categories and Pandharipande-Thomas (PT) categories, giving a categorical analogue of the numerical DT/PT correspondence for Calabi-Yau 3-folds. The main ingredient is a categorical wall-crossing formula for DT/PT quivers (which appear as […]


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Causal shadow and non-local modular flow: from degeneracy to perturbative genesis by correlation

Kavli Affiliate: Huajia Wang | First 5 Authors: Liangyu Chen, Huajia Wang, , , | Summary: Causal shadows are bulk space-time regions between the entanglement wedges and the causal wedges, their existence encodes deep aspects of the entanglement wedge reconstruction in the context of subregion duality in AdS/CFT. In this paper, we study the perturbation […]


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Coherent Sheaves, Chern Classes, and Superconnections on Compact Complex-Analytic Manifolds

Kavli Affiliate: Alexey Bondal | Summary:We construct a twist-closed enhancement of the category $mathcal D^b_rm coh(X)$, the bounded derived category of complexes of $mathcal O_X$-modules with coherent cohomology, by means of the DG-category of $barpartial$-superconnections. Then we apply the techniques of $barpartial$-superconnections to define Chern classes and Bott-Chern classes of objects in the category, in […]


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Electroconvective flow in presence of polyethylene glycol oligomer additives

Kavli Affiliate: Lynden Archer | Summary:Metal electrodeposition in batteries is fundamentally unstable and affected by different instabilities depending on operating conditions and chemical composition. Particularly at high charging rates, a hydrodynamic instability called electroconvection sets in that aggravates the situation by creating non-uniform ion flux and preferential deposition at the electrode. Here, we experimentally investigate […]


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