Personalized Dose Guidance using Safe Bayesian Optimization

Kavli Affiliate: Francis J. Doyle | First 5 Authors: Dinesh Krishnamoorthy, Francis J. Doyle III, , , | Summary: This work considers the problem of personalized dose guidance using Bayesian optimization that learns the optimum drug dose tailored to each individual, thus improving therapeutic outcomes. Safe learning using interior point method ensures patient safety with […]


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The BRAIN Initiative Cell Census Data Ecosystem: A User’s Guide

Kavli Affiliate: Michael Miller | Authors: BICCN Data Ecosytem Collaboration, Michael J Hawrylycz, Maryann E Martone, Patrick R Hof, Ed S Lein, Aviv Regev, Giorgio A. A Ascoli, Jan G Bjaalie, Hong-Wei Dong, Satrajit S Ghosh, Jesse Gillis, Ronna Hertzano, David R Haynor, Yongsoo Kim, Yufeng Liu, Jeremy A Miller, Partha P Mitra, Eran Mukamel, […]


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Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids

Kavli Affiliate: Vy Thuy Nguyen | Authors: Kim Vy Nguyen Ngoc, Somesh Sai, Yesl Jun, R. Hugh F. Bender, Vira Kravets, Han Zhu, Christopher J Hatch, Michael Schlichting, Roberto Gaetani, Medhavi Mallick, Stephanie J Hachey, Karen Christman, Steven Carl George, Christopher C Hughes and Maike Sander | Summary: Abstract Blood vessels play a critical role […]


Continue.. Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids