Personalized Dose Guidance using Safe Bayesian Optimization

Kavli Affiliate: Francis J. Doyle | First 5 Authors: Dinesh Krishnamoorthy, Francis J. Doyle III, , , | Summary: This work considers the problem of personalized dose guidance using Bayesian optimization that learns the optimum drug dose tailored to each individual, thus improving therapeutic outcomes. Safe learning using interior point method ensures patient safety with […]


Continue.. Personalized Dose Guidance using Safe Bayesian Optimization

The BRAIN Initiative Cell Census Data Ecosystem: A User’s Guide

Kavli Affiliate: Michael Miller | Authors: BICCN Data Ecosytem Collaboration, Michael J Hawrylycz, Maryann E Martone, Patrick R Hof, Ed S Lein, Aviv Regev, Giorgio A. A Ascoli, Jan G Bjaalie, Hong-Wei Dong, Satrajit S Ghosh, Jesse Gillis, Ronna Hertzano, David R Haynor, Yongsoo Kim, Yufeng Liu, Jeremy A Miller, Partha P Mitra, Eran Mukamel, […]


Continue.. The BRAIN Initiative Cell Census Data Ecosystem: A User’s Guide

Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids

Kavli Affiliate: Vy Thuy Nguyen | Authors: Kim Vy Nguyen Ngoc, Somesh Sai, Yesl Jun, R. Hugh F. Bender, Vira Kravets, Han Zhu, Christopher J Hatch, Michael Schlichting, Roberto Gaetani, Medhavi Mallick, Stephanie J Hachey, Karen Christman, Steven Carl George, Christopher C Hughes and Maike Sander | Summary: Abstract Blood vessels play a critical role […]


Continue.. Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids

Spin hydrodynamic generation in unsteady flows

Kavli Affiliate: Mamoru Matsuo | First 5 Authors: Takumi Funato, Mamoru Matsuo, , , | Summary: We theoretically investigate a spin-mediated conversion from fluid dynamics to voltage, known as spin hydrodynamic generation (SHDG), in oscillatory and transient unsteady flows. We consider unsteady flows of liquid metal between two parallel infinite planes and then calculate its […]


Continue.. Spin hydrodynamic generation in unsteady flows

Mass-Metallicity Relation during the Epoch of Reionization in the CROC Simulations

Kavli Affiliate: Nickolay Gnedin | First 5 Authors: Isaac Noel, Hanjue Zhu, Nickolay Gnedin, , | Summary: The low-redshift mass-metallicity relation (MZR) is well studied, but the high-redshift MZR remains difficult to observe. To study the early MZR further, we analyze the Cosmic Reionization on Computers (CROC) simulations with a focus on the MZR from […]


Continue.. Mass-Metallicity Relation during the Epoch of Reionization in the CROC Simulations