Astrocytic Gi-GPCR activation enhances stimulus-evoked extracellular glutamate

Posted by klaurent UCSF

Kavli Affiliate: Kira Poskanzer | Authors: Kira Poskanzer, Trisha V Vaidyanathan, Vincent Tse and Esther M Lim | Summary: Astrocytes perform critical functions in the nervous system, many of which are dependent on neurotransmitter-sensing through G protein-coupled receptors (GPCRs). However, whether specific astrocytic outputs follow specific GPCR activity remains unclear, and exploring this question is […]


Continue.. Astrocytic Gi-GPCR activation enhances stimulus-evoked extracellular glutamate

Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response

Posted by klaurent UCSD / Salk

Kavli Affiliate: Wesley Thompson | Authors: Meghana Pagadala, Victoria H. Wu, Eva Perez-Guijarro, Hyo Kim, Andrea Castro, James Talwar, Timothy Sears, Cristian Gonzalez-Colin, Steven Cao, Benjamin Schmiedel, Shervin Goudarzi, Divya Kirani, Rany Salem, Gerald Morris, Olivier Harismendy, Sandip Pravin Patel, Jill P. Mesirov, Maurizio Zanetti, Chi-Ping Day, Chun Chieh Fan, Wesley K. Thompson, Glenn Merlino, […]


Continue.. Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response

Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission

Posted by klaurent UCSD / Salk

Kavli Affiliate: Fred Gage | Authors: Shani Stern, Lei Zhang, Meiyan Wang, Rebecca Wright, Diogo Cordeiro, David Peles, Yuqing Hang, Ana P Mendes, Tithi Baul, Julien Roth, Shashank Coorapati, Marco Boks, Hilleke Hulshoff Pol, Kristen J. Brennand, Janos M Rethelyi, Rene S. Kahn, Maria C. Marchetto and Fred H. Gage | Summary: Schizophrenia affects approximately […]


Continue.. Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission

Transretinal migration of astrocytes and brain/spinal cord-like cells arising from transplanted human retinal organoids.

Posted by klaurent Hopkins

Kavli Affiliate: Seth Blackshaw | Authors: Ying Liu, Clayton Santiago, Akin Sogunro, Gregory K. Konar, Ming-Wen Hu, Minda M. McNally, Yuchen Lu, Zhuolin Li, Dzhalal Agakishiev, Sarah Hadyniak, Katarzyna Hussey, Tyler J. Creamer, Linda D. Orzolek, Derek Teng, Jiang Qian, Zheng Jiang, Robert J. Johnston, Jr., Seth Blackshaw and Mandeep S. Singh | Summary: Human […]


Continue.. Transretinal migration of astrocytes and brain/spinal cord-like cells arising from transplanted human retinal organoids.

Constraining Feeble Neutrino Interactions with Ultralight Dark Matter

Posted by klaurent Chicago

Kavli Affiliate: Gordan Krnjaic | First 5 Authors: Abhish Dev, Gordan Krnjaic, Pedro Machado, Harikrishnan Ramani, | Summary: If ultralight $(ll$ eV), bosonic dark matter couples to right handed neutrinos, active neutrino masses and mixing angles depend on the ambient dark matter density. When the neutrino Majorana mass, induced by the dark matter background, is […]


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Efficient Path Planning and Tracking for Multi-Modal Legged-Aerial Locomotion Using Integrated Probabilistic Road Maps (PRM) and Reference Governors (RG)

Posted by Caltech

Kavli Affiliate: Morteza Gharib | First 5 Authors: Eric Sihite, Benjamin Mottis, Paul Ghanem, Alireza Ramezani, Morteza Gharib | Summary: There have been several successful implementations of bio-inspired legged robots that can trot, walk, and hop robustly even in the presence of significant unplanned disturbances. Despite all of these accomplishments, practical control and high-level decision-making […]


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Abstract representations emerge naturally in neural networks trained to perform multiple tasks

Posted by klaurent Columbia

Kavli Affiliate: Stefano Fusi | Authors: W. Jeffrey Johnston and Stefano Fusi | Summary: Humans and other animals demonstrate a remarkable ability to generalize knowledge across distinct contexts and objects during natural behavior. We posit that this ability to generalize arises from a specific representational geometry, that we call abstract and that is referred to […]


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Can Carbon Fractionation Provide Evidence for Aerial Biospheres in the Atmospheres of Temperate Sub-Neptunes?

Posted by klaurent MIT

Kavli Affiliate: Sara Seager | First 5 Authors: Ana Glidden, Sara Seager, Jingcheng Huang, Janusz J. Petkowski, Sukrit Ranjan | Summary: The search for signs of life on other worlds has largely focused on terrestrial planets. Recent work, however, argues that life could exist in the atmospheres of temperate sub-Neptunes. Here, we evaluate the usefulness […]


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The Quadruple Image Configurations of Asymptotically Circular Gravitational Lenses

Posted by dbos MIT

Kavli Affiliate: Paul L. Schechter | First 5 Authors: Chirag Falor, Paul L. Schechter, , , | Summary: The quadruple image configurations of gravitational lenses with vanishing ellipticity are examined. Even though such lenses asymptotically approach circularity, the configurations are stable if the position of the source relative to the vanishing diamond caustic is held […]


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