A partnership of the lipid scramblase XK and of the lipid transfer protein VPS13A at the plasma membrane

Kavli Affiliate: Pietro DeCamilli | Authors: Andrés Guillén Samander, Yumei Wu, S. Sebastian Pineda, Francisco J. García, Julia N. Eisen, Marianna Leonzino, Berrak Uğur, Manolis Kellis, Myriam Heiman and Pietro De Camilli | Summary: Chorea-acanthocytosis and McLeod syndrome are diseases with shared clinical manifestations caused by mutations in VPS13A and XK, respectively. Key features of […]


Continue.. A partnership of the lipid scramblase XK and of the lipid transfer protein VPS13A at the plasma membrane

Knowledge-Spreader: Learning Facial Action Unit Dynamics with Extremely Limited Labels

Kavli Affiliate: Xiang Zhang | First 5 Authors: Xiaotian Li, Xiang Zhang, Taoyue Wang, Lijun Yin, | Summary: Recent studies on the automatic detection of facial action unit (AU) have extensively relied on large-sized annotations. However, manually AU labeling is difficult, time-consuming, and costly. Most existing semi-supervised works ignore the informative cues from the temporal […]


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Mesoscopic oblique plane microscopy (Meso-OPM) – enabling large-scale 4D isotropic cellular resolution imaging with a diffractive light sheet

Kavli Affiliate: Patrick Kanold | Authors: Wenjun Shao, Minzi Chang, Kevin Emmerich, Patrick O Kanold, Jeff S Mumm and Ji Yi | Summary: Fundamental understanding of large-scale dynamic connectivity within a living organism requires volumetric imaging over a large field of view (FOV) at biologically relevant speed and resolution. However, most microscopy methods make trade-offs […]


Continue.. Mesoscopic oblique plane microscopy (Meso-OPM) – enabling large-scale 4D isotropic cellular resolution imaging with a diffractive light sheet

A Fast and Convergent Proximal Algorithm for Regularized Nonconvex and Nonsmooth Bi-level Optimization

Kavli Affiliate: Yi Zhou | First 5 Authors: Ziyi Chen, Bhavya Kailkhura, Yi Zhou, , | Summary: Many important machine learning applications involve regularized nonconvex bi-level optimization. However, the existing gradient-based bi-level optimization algorithms cannot handle nonconvex or nonsmooth regularizers, and they suffer from a high computation complexity in nonconvex bi-level optimization. In this work, […]


Continue.. A Fast and Convergent Proximal Algorithm for Regularized Nonconvex and Nonsmooth Bi-level Optimization

A Fast and Convergent Proximal Algorithm for Regularized Nonconvex and Nonsmooth Bi-level Optimization

Kavli Affiliate: Yi Zhou | First 5 Authors: Ziyi Chen, Bhavya Kailkhura, Yi Zhou, , | Summary: Many important machine learning applications involve regularized nonconvex bi-level optimization. However, the existing gradient-based bi-level optimization algorithms cannot handle nonconvex or nonsmooth regularizers, and they suffer from a high computation complexity in nonconvex bi-level optimization. In this work, […]


Continue.. A Fast and Convergent Proximal Algorithm for Regularized Nonconvex and Nonsmooth Bi-level Optimization

Searching for axion-like time-dependent cosmic birefringence with data from SPT-3G

Kavli Affiliate: Chao-Lin Kuo | First 5 Authors: K. R. Ferguson, A. J. Anderson, N. Whitehorn, P. A. R. Ade, M. Archipley | Summary: Ultralight axionlike particles (ALPs) are compelling dark matter candidates because of their potential to resolve small-scale discrepancies between $Lambda$CDM predictions and cosmological observations. Axion-photon coupling induces a polarization rotation in linearly […]


Continue.. Searching for axion-like time-dependent cosmic birefringence with data from SPT-3G

Searching for axion-like time-dependent cosmic birefringence with SPT-3G

Kavli Affiliate: Chao-Lin Kuo | First 5 Authors: K. R. Ferguson, A. J. Anderson, N. Whitehorn, P. A. R. Ade, M. Archipley | Summary: Ultralight axion-like particles (ALPs) are compelling dark matter candidates because of their potential to resolve small-scale discrepancies between $Lambda$CDM predictions and cosmological observations. Axion-photon coupling induces a polarization rotation in linearly […]


Continue.. Searching for axion-like time-dependent cosmic birefringence with SPT-3G

The Latest Constraints on Inflationary B-modes from the BICEP/Keck Telescopes

Kavli Affiliate: Chao-Lin Kuo | First 5 Authors: BICEP/Keck Collaboration, :, P. A. R. Ade, Z. Ahmed, M. Amiri | Summary: For the past decade, the BICEP/Keck collaboration has been operating a series of telescopes at the Amundsen-Scott South Pole Station measuring degree-scale $B$-mode polarization imprinted in the Cosmic Microwave Background (CMB) by primordial gravitational […]


Continue.. The Latest Constraints on Inflationary B-modes from the BICEP/Keck Telescopes