Violation of the ultrastructural size principle in the dorsolateral prefrontal cortex underlies working memory impairment in the aged common marmoset (Callithrix jacchus)

Posted by klaurent UCSD / Salk

Kavli Affiliate: John Reynolds | Authors: Courtney Glavis-Bloom, Casey R Vanderlip, Sammy Weiser Novak, Masaaki Kuwajima, Lyndsey Kirk, Uri Manor, Kristen M Harris and John H Reynolds | Summary: ABSTRACT Working memory relies critically on the dorsolateral prefrontal cortex (dlPFC). Morphology and function of the dlPFC, and corresponding working memory performance, are affected early in […]


Continue.. Violation of the ultrastructural size principle in the dorsolateral prefrontal cortex underlies working memory impairment in the aged common marmoset (Callithrix jacchus)

Generative network modeling reveals quantitative definitions of bilateral symmetry exhibited by a whole insect brain connectome

Posted by klaurent Hopkins

Kavli Affiliate: Carey Priebe, Joshua Vogelstein | Authors: Benjamin D. Pedigo, Mike Powell, Eric W. Bridgeford, Michael Winding, Carey E. Priebe and Joshua T. Vogelstein | Summary: Abstract Comparing connectomes can help explain how neural connectivity is related to genetics, disease, development, learning, and behavior. However, making statistical inferences about the significance and nature of […]


Continue.. Generative network modeling reveals quantitative definitions of bilateral symmetry exhibited by a whole insect brain connectome

Predicting pathways for old and new metabolites through clustering

Posted by Caltech

Kavli Affiliate: Nathan Lewis | First 5 Authors: Thiru Siddharth, Nathan Lewis, , , | Summary: The diverse metabolic pathways are fundamental to all living organisms, as they harvest energy, synthesize biomass components, produce molecules to interact with the microenvironment, and neutralize toxins. While discovery of new metabolites and pathways continues, the prediction of pathways […]


Continue.. Predicting pathways for old and new metabolites through clustering

Understanding binary phase separation towards Cu-C nanocrystalline-amorphous composites

Posted by Caltech

Kavli Affiliate: Wei Gao | First 5 Authors: Jiajian Guan, Qin Jiang, Yue He, Xu Zhang, Bin Liao | Summary: The nanocrystalline-amorphous textures are commonly observed in the coatings synthesized by energetic deposition.This work reports a theoretical study towards binary Cu-C phase separation.By performing a MD simulation using the LAMMPS instead of classical PFK methodology, […]


Continue.. Understanding binary phase separation towards Cu-C nanocrystalline-amorphous composites

Understanding binary phase separation towards Cu-C nanocrystalline-amorphous composites

Posted by Caltech

Kavli Affiliate: Wei Gao | First 5 Authors: Jiajian Guan, Qin Jiang, Yue He, Xu Zhang, Bin Liao | Summary: The nanocrystalline-amorphous textures are commonly observed in the coatings synthesized by energetic deposition.This work reports a theoretical study towards binary Cu-C phase separation.By performing a MD simulation using the LAMMPS instead of classical PFK methodology, […]


Continue.. Understanding binary phase separation towards Cu-C nanocrystalline-amorphous composites

Detection of stellar light from quasar host galaxies at redshifts above 6

Posted by klaurent Tokyo

Kavli Affiliate: John D. Silverman | First 5 Authors: Xuheng Ding, Masafusa Onoue, John D. Silverman, Yoshiki Matsuoka, Takuma Izumi | Summary: The detection of starlight from the host galaxies of quasars during the reionization epoch ($z>6$) has been elusive, even with deep HST observations. The current highest redshift quasar host detected, at $z=4.5$, required […]


Continue.. Detection of stellar light from quasar host galaxies at redshifts above 6

Detection of stellar light from quasar host galaxies at redshifts above 6

Posted by klaurent Tokyo

Kavli Affiliate: John D. Silverman | First 5 Authors: Xuheng Ding, Masafusa Onoue, John D. Silverman, Yoshiki Matsuoka, Takuma Izumi | Summary: The detection of starlight from the host galaxies of quasars during the reionization epoch ($z>6$) has been elusive, even with deep HST observations. The current highest redshift quasar host detected, at $z=4.5$, required […]


Continue.. Detection of stellar light from quasar host galaxies at redshifts above 6

BDNF and TRiC-inspired Reagents Rescue Cortical Synaptic Deficits in a Mouse Model of Huntington’s Disease

Posted by klaurent UCSD / Salk

Kavli Affiliate: William Mobley | Authors: Yingli Gu, Alexander Pope, Charlene Smith-Geater, Christopher Carmona, Aaron Johnstone, Linda Shi, Xuqiao Chen, Sarai Santos, Claire C Bacon-Brenes, Thomas Shoff, Korbin M Kleczko, Judith Frydman, Leslie M Thompson, William C Mobley and Chengbiao Wu | Summary: Abstract Huntington’s disease (HD) results from a CAG repeat expansion in the […]


Continue.. BDNF and TRiC-inspired Reagents Rescue Cortical Synaptic Deficits in a Mouse Model of Huntington’s Disease