Sensitivity analysis for publication bias on the time-dependent summary ROC analysis in meta-analysis of prognosis studies

Kavli Affiliate: Yi Zhou | First 5 Authors: Yi Zhou, Ao Huang, Satoshi Hattori | Summary: In the analysis of prognosis studies with time-to-event outcomes, dichotomization of patients is often made. As the evaluations of prognostic capacity, the survivals of groups with high/low expression of the biomarker are often estimated by the Kaplan-Meier method, and […]


Continue.. Sensitivity analysis for publication bias on the time-dependent summary ROC analysis in meta-analysis of prognosis studies

Discovering New Interpretable Conservation Laws as Sparse Invariants

Kavli Affiliate: Max Tegmark | First 5 Authors: Ziming Liu, Patrick Obin Sturm, Saketh Bharadwaj, Sam Silva, Max Tegmark | Summary: Discovering conservation laws for a given dynamical system is important but challenging. In a theorist setup (differential equations and basis functions are both known), we propose the Sparse Invariant Detector (SID), an algorithm that […]


Continue.. Discovering New Interpretable Conservation Laws as Sparse Invariants

An Open-Source Tool for Automated Human-Level Circling Behavior Detection

Kavli Affiliate: Kathleen Cullen | Authors: Oliver R Stanley, Ananya Swaminathan, Elias Wojahn, Zubair M Ahmed and Kathleen E Cullen | Summary: Quantifying behavior and relating it to underlying biological states is of paramount importance in many life science fields. Although barriers to recording postural data have been reduced by progress in deep-learning-based computer vision […]


Continue.. An Open-Source Tool for Automated Human-Level Circling Behavior Detection

Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels

Kavli Affiliate: Kathleen Cullen | Authors: Arnaud P. J. Giese, Wei-Hsiang Weng, Katie S Kindt, Vanessa H. H. Chang, Jonathan S Montgomery, Evan M. Ratzan, Alisha J. Beirl, Roberto Aponte Rivera, Jeffrey M. Lotthammer, Sanket Walujkar, Mark P. Foster, Omid A. Zobeiri, Jeffrey R. Holt, Saima Riazuddin, Kathleen E. Cullen, Marcos Sotomayor and Zubair M […]


Continue.. Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels

Glaucoma-associated Optineurin mutations increase transmitophagy in a vertebrate optic nerve

Kavli Affiliate: Mark Ellisman | Authors: Yaeram Jeong, chung-ha Davis, Aaron Muscarella, Viraj Deshpande, Keun-Young Kim, Mark Ellisman and Nicholas Marsh-Armstrong | Summary: We previously described a process referred to as transmitophagy where mitochondria shed by retinal ganglion cell (RGC) axons are transferred to and degraded by surrounding astrocytes in the optic nerve head of […]


Continue.. Glaucoma-associated Optineurin mutations increase transmitophagy in a vertebrate optic nerve

Population II Distance Indicators: RR Lyrae Variables, Tip of the Red Giant Branch (TRGB) Stars and J-Branch Asymptotic Giant Branch (JAGB/Carbon) Stars

Kavli Affiliate: Wendy L. Freedman | First 5 Authors: Barry F. Madore, Wendy L. Freedman, , , | Summary: We review the theoretical underpinnings, evolutionary status, calibrations and current applications of three bright Population II extragalactic distance indicators: Tip of the Red Giant Branch (TRGB) stars, RR Lyrae variables and J-Branch Asymptotic Giant Branch (JAGB/Carbon) […]


Continue.. Population II Distance Indicators: RR Lyrae Variables, Tip of the Red Giant Branch (TRGB) Stars and J-Branch Asymptotic Giant Branch (JAGB/Carbon) Stars

JADES + JEMS: A Detailed Look at the Buildup of Central Stellar Cores and Suppression of Star Formation in Galaxies at Redshifts 3 < z < 4.5

Kavli Affiliate: Roberto Maiolino | First 5 Authors: Zhiyuan Ji, Christina C. Williams, Sandro Tacchella, Katherine A. Suess, William M. Baker | Summary: We present a spatially resolved study of stellar populations in 6 galaxies with stellar masses $M_*sim10^{10}M_odot$ at $zsim3.7$ using 14-filter JWST/NIRCam imaging from the JADES and JEMS surveys. The 6 galaxies are […]


Continue.. JADES + JEMS: A Detailed Look at the Buildup of Central Stellar Cores and Suppression of Star Formation in Galaxies at Redshifts 3 < z < 4.5