Lysosomal TBK1 Responds to Amino Acid Availability to Relieve Rab7-Dependent mTORC1 Inhibition

Posted by dbos Yale

Kavli Affiliate: Shawn Ferguson | Authors: Gabriel Talaia, Amanda Bentley-DeSousa and Shawn Ferguson | Summary: Lysosomes play a pivotal role in coordinating macromolecule degradation and regulating cell growth and metabolism. Despite substantial progress in identifying lysosomal signaling proteins, understanding the pathways that synchronize lysosome functions with changing cellular demands remains incomplete. This study uncovers a […]


Continue.. Lysosomal TBK1 Responds to Amino Acid Availability to Relieve Rab7-Dependent mTORC1 Inhibition

Host–pathogen–vector continuum in a changing landscape: Drivers of Bartonella prevalence and evidence of historic spillover in a multi–host community

Posted by dbos Rockefeller, Yale

Kavli Affiliate: V. S. Ramachandran | Authors: B.R. Ansil, Ashwin Viswanathan, Vivek Ramachandran, H.M. Yeshwanth, Avirup Sanyal and Uma Ramakrishnan | Summary: Small mammals and their ectoparasites present a unique system to investigate the eco-epidemiology of multi-host vector-borne pathogens and identify specific bacterial spillover determinants. We applied ecological and evolutionary analyses in a rainforest-human-use mosaic […]


Continue.. Host–pathogen–vector continuum in a changing landscape: Drivers of Bartonella prevalence and evidence of historic spillover in a multi–host community

VecFusion: Vector Font Generation with Diffusion

Posted by dbos UCSB

Kavli Affiliate: Matthew Fisher | First 5 Authors: Vikas Thamizharasan, Difan Liu, Shantanu Agarwal, Matthew Fisher, Michael Gharbi | Summary: We present VecFusion, a new neural architecture that can generate vector fonts with varying topological structures and precise control point positions. Our approach is a cascaded diffusion model which consists of a raster diffusion model […]


Continue.. VecFusion: Vector Font Generation with Diffusion

VecFusion: Vector Font Generation with Diffusion

Posted by dbos UCSB

Kavli Affiliate: Matthew Fisher | First 5 Authors: Vikas Thamizharasan, Difan Liu, Shantanu Agarwal, Matthew Fisher, Michael Gharbi | Summary: We present VecFusion, a new neural architecture that can generate vector fonts with varying topological structures and precise control point positions. Our approach is a cascaded diffusion model which consists of a raster diffusion model […]


Continue.. VecFusion: Vector Font Generation with Diffusion

VecFusion: Vector Font Generation with Diffusion

Posted by dbos UCSB

Kavli Affiliate: Matthew Fisher | First 5 Authors: Vikas Thamizharasan, Difan Liu, Shantanu Agarwal, Matthew Fisher, Michael Gharbi | Summary: We present VecFusion, a new neural architecture that can generate vector fonts with varying topological structures and precise control point positions. Our approach is a cascaded diffusion model which consists of a raster diffusion model […]


Continue.. VecFusion: Vector Font Generation with Diffusion

JWST Early Release Science Program TEMPLATES: Targeting Extremely Magnified Panchromatic Lensed Arcs and their Extended Star formation

Posted by dbos Chicago

Kavli Affiliate: Michael D. Gladders | First 5 Authors: Jane R. Rigby, Joaquin D. Vieira, Kedar A. Phadke, Taylor A. Hutchison, Brian Welch | Summary: This paper gives an overview of TEMPLATES, a JWST Early Release Science program that targeted four extremely bright, gravitationally lensed galaxies: two extremely dusty, two with low attenuation, as templates […]


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ElasticLaneNet: A Geometry-Flexible Approach for Lane Detection

Posted by dbos Peking

Kavli Affiliate: Feng Yuan | First 5 Authors: Yaxin Feng, Yuan Lan, Luchan Zhang, Yang Xiang, | Summary: The task of lane detection involves identifying the boundaries of driving areas. Recognizing lanes with complex and variable geometric structures remains a challenge. In this paper, we introduce a new lane detection framework named ElasticLaneNet (Elastic-interaction-energy guided […]


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ElasticLaneNet: An Efficient Geometry-Flexible Approach for Lane Detection

Posted by dbos Peking

Kavli Affiliate: Feng Yuan | First 5 Authors: Yaxin Feng, Yuan Lan, Luchan Zhang, Yang Xiang, | Summary: The task of lane detection involves identifying the boundaries of driving areas in real-time. Recognizing lanes with variable and complex geometric structures remains a challenge. In this paper, we explore a novel and flexible way of implicit […]


Continue.. ElasticLaneNet: An Efficient Geometry-Flexible Approach for Lane Detection

ElasticLaneNet: An Efficient Geometry-Flexible Approach for Lane Detection

Posted by dbos Peking

Kavli Affiliate: Feng Yuan | First 5 Authors: Yaxin Feng, Yuan Lan, Luchan Zhang, Yang Xiang, | Summary: The task of lane detection involves identifying the boundaries of driving areas in real-time. Recognizing lanes with variable and complex geometric structures remains a challenge. In this paper, we explore a novel and flexible way of implicit […]


Continue.. ElasticLaneNet: An Efficient Geometry-Flexible Approach for Lane Detection

Acute Neuropixels recordings in the marmoset monkey

Posted by dbos UCSD / Salk

Kavli Affiliate: John Reynolds | Authors: Nicholas M Dotson, Zachary W Davis, Patrick Jendritza and John H Reynolds | Summary: High-density linear probes, like Neuropixels, provide an unprecedented opportunity to understand how neural populations within specific laminar compartments contribute to behavior. Marmoset monkeys, unlike macaque monkeys, have a lissencephalic (smooth) cortex that enables recording perpendicular […]


Continue.. Acute Neuropixels recordings in the marmoset monkey