WormID-Benchmark: Extracting Whole-Brain Neural Dynamics of C. elegans At the Neuron Resolution

Kavli Affiliate: Saul Kato | Authors: Jason Adhinarta, Jizheng Dong, Tianxiao He, Daniel Sprague, JIa Wan, Hyun Jee Lee, Zikai Yu, Hang Lu, Eviatar Yemini, Saul Kato, Erdem Varol and Donglai Wei | Summary: The nematode C. elegans is a well-studied model organism for characterizing the structure, connectivity, and function of a complete nervous system. […]


Continue.. WormID-Benchmark: Extracting Whole-Brain Neural Dynamics of C. elegans At the Neuron Resolution

Pathological microcircuits initiate epileptiform events in patient hippocampal slices

Kavli Affiliate: Edward Chang | Authors: Matthew Elliott, John P. Andrews, Tjitse van der Molen, Jinghui Geng, Alex Spaeth, Anna Toledo, Kateryna Voitiuk, Cordero Core, Thomas Gillespie, Ari Sinervo, David F. Parks, Ash Robbins, Daniel Solis, Edward F. Chang, Tomasz J Nowakowski, Mircea Teodorescu, David Haussler and Tal Sharf | Summary: How seizures begin at […]


Continue.. Pathological microcircuits initiate epileptiform events in patient hippocampal slices

Functional organization and natural scene responses across mouse visual cortical areas revealed with encoding manifolds

Kavli Affiliate: Michael Stryker | Authors: Luciano Dyballa, Greg D Field, Michael P Stryker and Steven W Zucker | Summary: A challenge in sensory neuroscience is understanding how populations of neurons operate in concert to represent diverse stimuli. To meet this challenge, we have created “encoding manifolds” that reveal the overall responses of brain areas […]


Continue.. Functional organization and natural scene responses across mouse visual cortical areas revealed with encoding manifolds

Not all cross-modal responses are explained by face movements

Kavli Affiliate: Andrea Hasenstaub | Authors: Timothy R Olsen and Andrea R Hasenstaub | Summary: Recent work has claimed that most apparently cross-modal responses in sensory cortex are instead caused by the face movements evoked by stimuli of the non-dominant modality. We show that visual stimuli rarely trigger face movements in awake mice; when they […]


Continue.. Not all cross-modal responses are explained by face movements

Multiscale Cloud-based Pipeline for Neuronal Electrophysiology Analysis and Visualization

Kavli Affiliate: Edward Chang | Authors: Jinghui Geng, Kateryna Voitiuk, David F. Parks, Ash Robbins, Alex Spaeth, Jessica L. Sevetson, Sebastian Hernandez, Hunter E. Schweiger, John P. Andrews, Spencer T. Seiler, Matthew A. T. Elliott, Edward F. Chang, Tomasz J. Nowakowski, Rob Currie, Mohammed A. Mostajo-Radji, David Haussler, Tal Sharf, Sofie R. Salama and Mircea […]


Continue.. Multiscale Cloud-based Pipeline for Neuronal Electrophysiology Analysis and Visualization

Motor learning leverages coordinated low-frequency cortico-basal ganglia activity to optimize motor preparation in humans with Parkinson’s Disease

Kavli Affiliate: Jeremy Willsey | Authors: Elina Kostyanovskaya, Micaela C. Lasser, Belinda Wang, James Schmidt, Ethel Bader, Chad Buteo, Juan Arbelaez, Aria Rani Sindledecker, Kate E. McCluskey, Octavio Castillo, Sheng Wang, Jeanselle Dea, Kathryn A. Helde, J. Michael Graglia, Elise Brimble, David B. Kastner, Aliza T. Ehrlich, Matthew W. State, A. Jeremy Willsey and Helen […]


Continue.. Motor learning leverages coordinated low-frequency cortico-basal ganglia activity to optimize motor preparation in humans with Parkinson’s Disease

Convergence of autism proteins at the cilium

Kavli Affiliate: Jeremy Willsey | Authors: Elina Kostyanovskaya, Micaela C. Lasser, Belinda Wang, James Schmidt, Ethel Bader, Chad Buteo, Juan Arbelaez, Aria Rani Sindledecker, Kate E. McCluskey, Octavio Castillo, Sheng Wang, Jeanselle Dea, Kathryn A. Helde, J. Michael Graglia, Elise Brimble, David B. Kastner, Aliza T. Ehrlich, Matthew W. State, A. Jeremy Willsey and Helen […]


Continue.. Convergence of autism proteins at the cilium

Oxytocin receptor controls promiscuity and development in prairie voles

Kavli Affiliate: Devanand Manoli and Jeremy Willsey | Authors: Ruchira Sharma, Kristen M. Berendzen, Amanda Everitt, Belinda Wang, Gina Williams, Shuyu Wang, Kara Quine, Rose D. Larios, Kimberly L. P. Long, Nerissa Hoglen, Bibi Alika Sulaman, Marie C. Heath, Michael Sherman, Robert Klinkel, Angela Cai, Denis Galo, Lizandro Chan Caamal, Nastacia L. Goodwin, Annaliese Beery, […]


Continue.. Oxytocin receptor controls promiscuity and development in prairie voles

Mapping cis- and trans-regulatory target genes of human-specific deletions

Kavli Affiliate: Alex Pollen | Authors: Tyler Fair, Bryan J Pavlovic, Dani Swope, Octavio E Castillo, Nathan K Schaefer and Alex Aaron Pollen | Summary: Deletion of functional sequence is predicted to represent a fundamental mechanism of molecular evolution. Comparative genetic studies of primates have identified thousands of human-specific deletions (hDels), and the cis-regulatory potential […]


Continue.. Mapping cis- and trans-regulatory target genes of human-specific deletions

Genome Organization with CUT and Tag (GO-CaT) identifies substructure and maturation of lamina-associated domains in neurons of the developing human brain

Kavli Affiliate: Arnold R. Kriegstein | Authors: Chujing Zhang, Eugene Gil, Sajad Hamid Ahanger, Mingcong Li, Li Wang, Jingjing Li, Arnold Kriegstein and Daniel Lim | Summary: Approximately 30-40% of the human genome is anchored to the nuclear lamina through variably sized (10 kb–10 Mb) lamina-associated domains (LADs). Previous work in cultured murine and human […]


Continue.. Genome Organization with CUT and Tag (GO-CaT) identifies substructure and maturation of lamina-associated domains in neurons of the developing human brain