Mapping general anesthesia states based on electro-encephalogram transition phases

Posted by klaurent UCSF

Kavli Affiliate: Jeanne Paz | Authors: Virginie Loison, Yuliya Voskobiynyk, Britta Lindquist, Deanna Necula, Dan Longrois, Jeanne T. Paz and David Holcman | Summary: Cortical electro-encephalography (EEG) has become the clinical reference for monitoring unconsciousness during general anesthesia. The current EEG-based monitors classify general anesthesia states simply as underdosed, adequate, or overdosed, with no transition […]


Continue.. Mapping general anesthesia states based on electro-encephalogram transition phases

Emergence of brain-like mirror-symmetric viewpoint tuning in convolutional neural networks

Posted by klaurent Rockefeller

Kavli Affiliate: Winrich Freiwald | Authors: Amirhossein Farzmahdi, Wilbert Zarco, Winrich Freiwald, Nikolaus Kriegeskorte and Tal Golan | Summary: Primates can recognize objects despite 3D geometric variations such as in-depth rotations. The computational mechanisms that give rise to such invariances are yet to be fully understood. A curious case of partial invariance occurs in the […]


Continue.. Emergence of brain-like mirror-symmetric viewpoint tuning in convolutional neural networks

Barley cultivars shape the abundance, phenotype, genotype and gene expression of their associated microbiota by differential root exudate secretion

Posted by klaurent UCSD / Salk

Kavli Affiliate: V. S. Ramachandran | Authors: Alba Pacheco-Moreno, Anita Bollmann-Giolai, Govind Chandra, Paul Brett, Jack Davies, Owen Thornton, Philip Poole, Vinoy Ramachandran, James Brown, Paul Nicholson, Chris Ridout, Sarah DeVos and Jacob G. Malone | Summary: Plant associated microbes play vital roles in promoting plant growth and health, with plants secreting root exudates into […]


Continue.. Barley cultivars shape the abundance, phenotype, genotype and gene expression of their associated microbiota by differential root exudate secretion

Mitochondria morphology governs ATP production rate

Posted by klaurent UCSD / Salk

Kavli Affiliate: Terrence Sejnowski | Authors: Guadalupe C. Garcia, Kavya Gupta, Thomas M. Bartol, Jr., Terrence J. Sejnowski and Padmini Rangamani | Summary: Life is based on energy conversion. In particular, in the nervous system significant amounts of energy are needed to maintain synaptic transmission and homeostasis. To a large extent, neurons depend on oxidative […]


Continue.. Mitochondria morphology governs ATP production rate

A unified framework to identify demographic buffering in natural populations

Posted by klaurent UCSD / Salk

Kavli Affiliate: Gabriel Silva | Authors: Gabriel Silva Santos, Samuel J L Gascoigne, Andre Tavares Correia Dias, Maja Kajin and Rob Salguero-Gomez | Summary: The Demographic Buffering Hypothesis (DBH) predicts that natural selection reduces the temporal fluctuations in demographic processes (such as survival, development, and reproduction), due to their negative impacts on population dynamics. However, […]


Continue.. A unified framework to identify demographic buffering in natural populations

Cognitive rehabilitation can improve brain injury-induced deficits in behavioral flexibility and impulsivity linked to impaired reward-feedback activity.

Posted by klaurent UCSD / Salk

Kavli Affiliate: Dhakshin Ramanathan | Authors: Miranda Francoeur Koloski, Christopher M O’Hearn, Michelle Frankot, Lauren P Giesler, Dhakshin S Ramanathan and Cole Vonder Haar | Summary: Traumatic brain injury (TBI) affects a large population, resulting in severe cognitive impairments. Although cognitive rehabilitation is an accepted treatment for some deficits, studies in patients are limited in […]


Continue.. Cognitive rehabilitation can improve brain injury-induced deficits in behavioral flexibility and impulsivity linked to impaired reward-feedback activity.

TrkB-dependent regulation of molecular signaling across septal cell types

Posted by klaurent Hopkins

Kavli Affiliate: Keri Martinowich | Authors: Lionel A Rodriguez, Matt N Tran, Renee Garcia-Flores, Elizabeth A Pattie, Sun-Hong Kim, Joo Heon Shin, Yong Kyu Lee, Heena R Divecha, Carly Montoya, Andrew E Jaffe, Leonardo Collado Torres, Stephanie Cerceo Page and Keri Martinowich | Summary: The lateral septum (LS), a GABAergic structure located in the basal […]


Continue.. TrkB-dependent regulation of molecular signaling across septal cell types

Scalable, accessible, and reproducible reference genome assembly and evaluation in Galaxy

Posted by klaurent Rockefeller

Kavli Affiliate: Erich Jarvis | Authors: Delphine Lariviere, Linelle Abueg, Nadolina Brajuka, Cristobal Gallardo-Alba, Bjorn Gruning, Byung June Ko, Alex Ostrovsky, Marc Palmada-Flores, Brandon D. Pickett, Keon Rabbani, Jennifer R. Balacco, Mark Chaisson, Haoyu Cheng, Joanna Collins, Alexandra Denisova, Olivier Fedrigo, Guido Roberto Gallo, Alice Maria Giani, Grenville MacDonald Gooder, Nivesh Jain, Cassidy Johnson, Heebal […]


Continue.. Scalable, accessible, and reproducible reference genome assembly and evaluation in Galaxy

Encoding and context-dependent control of reward consumption within the central nucleus of the amygdala

Posted by klaurent Hopkins

Kavli Affiliate: Patricia Janak | Authors: Kurt M. Fraser, Tabitha H. Kim, Matilde Castro, Céline Drieu, Yasmin Padovan-Hernandez, Bridget Chen, Fiona Pat, David J. Ottenheimer and Patricia H. Janak | Summary: The ability to evaluate and select a preferred option among a variety of available offers is an essential aspect of goal-directed behavior. Dysregulation of […]


Continue.. Encoding and context-dependent control of reward consumption within the central nucleus of the amygdala

Combinatorial transcription factor binding encodes cis-regulatory wiring of forebrain GABAergic neurogenesis

Posted by klaurent UCSF

Kavli Affiliate: John Rubenstein | Authors: Rinaldo Catta-Preta, Susan Lindtner, Athena Ypsilanti, James Price, Armen Abnousi, Linda Su-Feher, Yurong Wang, Ivan Juric, Ian Jones, Jennifer Akiyama, Ming Hu, Yin Shen, Axel Visel, Len Pennacchio, Diane Dickel, John Rubenstein and Alex Nord | Summary: Transcription factors (TFs) bind combinatorially to genomic cis-regulatory elements (cREs), orchestrating transcription […]


Continue.. Combinatorial transcription factor binding encodes cis-regulatory wiring of forebrain GABAergic neurogenesis