Generation and characterization of a multi-functional panel of monoclonal antibodies for SARS-CoV-2 research and treatment

Posted by dbos Rockefeller

Kavli Affiliate: Charles M. Rice | Authors: Lila D. Patterson, Benjamin D. Dubansky, Brooke H. Dubansky, Shannon Stone, Mukesh Kumar and Charles D Rice | Summary: The Coronavirus disease 2019 (COVID19) pandemic caused by Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) is an ongoing threat to global public health. To this end, intense efforts are underway to […]


Continue.. Generation and characterization of a multi-functional panel of monoclonal antibodies for SARS-CoV-2 research and treatment

Social isolation recruits amygdala-cortical circuitry to escalate alcohol drinking

Posted by dbos UCSD / Salk

Kavli Affiliate: Kay Tye | Authors: Reesha Patel, Makenzie Patarino, Kelly Kim, Rachelle Pamintuan, Felix Taschbach, Hao Li, Christopher Lee, Aniek van Hoek, Rogelio Castro, Christian Cazares, Ray Miranda, Caroline Jia, Jeremy Delahanty, Kanha Batra, Laurel Keyes, Avraham Libster, Romy W. Wichmann, Talmo Pereira, Marcus Benna and Kay M. Tye | Summary: How do social […]


Continue.. Social isolation recruits amygdala-cortical circuitry to escalate alcohol drinking

A combined DTI-fMRI approach for optimizing the delineation of posteromedial vs. anterolateral entorhinal cortex

Posted by dbos NTNU

Kavli Affiliate: Menno Witter | Authors: Ingrid Framas Syversen, Daniel Reznik, Menno P. Witter, Asgeir Kobro-Flatmoen, Tobias Navarro Schroder and Christian F. Doeller | Summary: In the entorhinal cortex (EC), attempts have been made to identify the human homologue regions of the medial (MEC) and lateral (LEC) subdivision using either functional magnetic resonance imaging (fMRI) […]


Continue.. A combined DTI-fMRI approach for optimizing the delineation of posteromedial vs. anterolateral entorhinal cortex

SELENOT regulates endoplasmic reticulum calcium flux via SERCA2 and maintains dopaminergic DAT to protect against attention deficit hyperactivity disorder in mice

Posted by dbos Rockefeller

Kavli Affiliate: Li Zhao | Authors: Qing Guo, Zhao-Feng Li, Dong-Yan Hu, Pei-Jun Li, Kai-Nian Wu, Hui-Hui Fan, Jie Deng, Hong-Mei Wu, Xiong Zhang and Jian-Hong Zhu | Summary: Attention deficit and hyperactivity disorder (ADHD) is a prevalent developmental disorder. SELENOT is an endoplasmic reticulum-resident selenocysteine-containing protein. We aimed to investigate the role of SELENOT […]


Continue.. SELENOT regulates endoplasmic reticulum calcium flux via SERCA2 and maintains dopaminergic DAT to protect against attention deficit hyperactivity disorder in mice

The entropic heart: Tracking the psychedelic state via heart rate dynamics

Posted by dbos UCSF

Kavli Affiliate: Reza Abbasi Asl & Adam Gazzaley | Authors: Fernando E. Rosas, Pedro A.M. Mediano, Christopher Timmermann, Andrea I Luppi, Diego Candia-Rivera, Reza Abbasi-Asl, Adam Gazzaley, Morten L Kringelbach, Suresh Daniel Muthukumaraswamy, Daniel Bor, Sarah Garfinkel and Robin Carhart-Harris | Summary: A growing body of work shows that autonomic signals provide a privileged evidence-stream […]


Continue.. The entropic heart: Tracking the psychedelic state via heart rate dynamics

Contexts facilitate dynamic value encoding in the mesolimbic dopamine system

Posted by dbos Hopkins

Kavli Affiliate: Patricia Janak | Authors: Kurt Michael Fraser, Val L Collins, Amy R Wolff, David J Ottenheimer, Kaisa N Bornhoft, Fiona Pat, Bridget J Chen, Patricia H Janak and Benjamin T Saunders | Summary: Adaptive behavior in a dynamic environment often requires rapid revaluation of stimuli that deviates from well-learned associations. The divergence between […]


Continue.. Contexts facilitate dynamic value encoding in the mesolimbic dopamine system

Electric fields determine carbapenemase activity in class A β-lactamases

Posted by dbos Hopkins

Kavli Affiliate: Michael Beer | Authors: Hira Jabeen, Michael Beer, James Spencer, Marc W van der Kamp, H Adrian Bunzel and Adrian J Mulholland | Summary: MAntimicrobial resistance is a public health crisis. Limited understanding of the catalytic drivers in resistance-mediating enzymes such as β-lactamases hinders our ability to combat this crisis. Here, we dissect […]


Continue.. Electric fields determine carbapenemase activity in class A β-lactamases

Male-male interactions shape mate selection in Drosophila

Posted by dbos Rockefeller

Kavli Affiliate: Vanessa Ruta | Authors: Tom Hindmarsh Sten, Rufei Li, Florian Hollunder, Shadé Eleazer and Vanessa Ruta | Summary: Males of many species have evolved behavioral traits to both attract females and repel rivals. Here, we explore mate selection in Drosophila from both the male and female perspective to shed light on how these […]


Continue.. Male-male interactions shape mate selection in Drosophila

Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

Posted by klaurent Hopkins

Kavli Affiliate: Denis Wirtz | Authors: Jeanette A.I. Johnson, Genevieve L Stein-O’Brien, Max Booth, Randy Heiland, Furkan Kurtoglu, Daniel Bergman, Elmar Bucher, Atul Deshpande, Andre Forjaz, Michael Getz, Ines Godet, Melissa Lyman, John Metzcar, Jacob Mitchell, Andrew Raddatz, Heber L. Rocha, Jacobo Solorzano, Aneequa Sundus, Yafei Wang, Daniele M. Gilkes, Luciane T. Kagohara, Ashley L. […]


Continue.. Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

Robust reprogramming of glia into neurons by inhibition of Notch signaling and NFI factors in adult mammalian retina.

Posted by dbos Hopkins

Kavli Affiliate: Seth Blackshaw | Authors: Nguyet Le, Trieu-Duc Vu, Isabella Palazzo, Ritvik Pulya, Yehna Kim, Seth Blackshaw and Thanh Hoang | Summary: Neurogenic competence is actively repressed in mature mammalian Muller glial cells, and previous studies have predicted that this is in part mediated by active Notch signaling. To determine whether global loss of […]


Continue.. Robust reprogramming of glia into neurons by inhibition of Notch signaling and NFI factors in adult mammalian retina.