Scaling use of the rust fungus Puccinia punctiformis for biological control of Canada thistle (Cirsium arvense (L.) Scop.): First report on a U.S. statewide effort

Kavli Affiliate: Robert E. Clark | Authors: Dan W. Bean, Kristi Gladem, Karen Rosen, Alexander Blake, Robert E. Clark, Caitlin Henderson, John Kaltenbach, Joel Price, Emily L. Smallwood, Dana K. Berner, Stephen L. Young and Robert N. Schaeffer | Summary: Canada thistle (Cirsium arvense (L.) Scop., CT) is one of the worst weeds threatening temperate […]


Continue.. Scaling use of the rust fungus Puccinia punctiformis for biological control of Canada thistle (Cirsium arvense (L.) Scop.): First report on a U.S. statewide effort

MAP1B Regulates Cortical Neuron Interstitial Axon Branching Through the Tubulin Tyrosination Cycle

Kavli Affiliate: Alex Kolodkin | Authors: Jakub Ziak, Joelle Dorskind, Brian Trigg, Sriram Sudarsanam, Randal Hand and Alex L Kolodkin | Summary: Regulation of directed axon guidance and branching during development is essential for the generation of neuronal networks. However, the molecular mechanisms that underlie interstitial axon branching in the mammalian brain remain unresolved. Here, […]


Continue.. MAP1B Regulates Cortical Neuron Interstitial Axon Branching Through the Tubulin Tyrosination Cycle

Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing

Kavli Affiliate: Liam Paninski | Authors: Marcus A. Triplett, Marta Gajowa, Benjamin Antin, Masato Sadahiro, Hillel Adesnik and Liam Paninski | Summary: Abstract Discovering how neural computations are implemented in the cortex at the level of monosynaptic connectivity requires probing for the existence of synapses from possibly thousands of presynaptic candidate neurons. Two-photon optogenetics has […]


Continue.. Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing

Leveraging the Adolescent Brain Cognitive Development Study to improve behavioral prediction from neuroimaging in smaller replication samples

Kavli Affiliate: Timothy Brown, Anders Dale | Authors: Carolina Makowski, Timothy T Brown, Weiqi Zhao, Donald J Hagler, Pravesh Parekh, Hugh Garavan, Thomas E Nichols, Terry L Jernigan and Anders M Dale | Summary: Magnetic resonance imaging (MRI) is a popular and useful non-invasive method to map patterns of brain structure and function to complex […]


Continue.. Leveraging the Adolescent Brain Cognitive Development Study to improve behavioral prediction from neuroimaging in smaller replication samples

Adolescent oligodendrogenesis and myelination restrict experience-dependent neuronal plasticity in adult visual cortex

Kavli Affiliate: Michael Stryker | Authors: Wendy Xin, Megumi Kaneko, Richard H Roth, Albert Zhang, Sonia Nocera, Jun B Ding, Michael P Stryker and Jonah R Chan | Summary: BACKGROUND: Developmental myelination is a protracted process in the mammalian brain. One theory for why oligodendrocytes mature so slowly posits that myelination may stabilize neuronal circuits […]


Continue.. Adolescent oligodendrogenesis and myelination restrict experience-dependent neuronal plasticity in adult visual cortex

Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation

Kavli Affiliate: Mary E. Hatten, C. David Allis | Authors: Lijuan Feng, Douglas Barrows, Liangwen Zhong, Kart Matlik, Elizabeth G. Porter, Annaelle M. Djomo, Iris Yau, Alexey A. Soshnev, Thomas S. Carroll, Duancheng Wen, Mary E. Hatten, Benjamin A. Garcia and C. David Allis | Summary: Chromatin is a crucial regulator of gene expression and […]


Continue.. Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation

Disruption of Epithelium Integrity by Inflammation-Associated Fibroblasts through Prostaglandin Signaling

Kavli Affiliate: Peter Searson | Authors: Yi Dong, Blake A Johns, Linhao Ruan, Maged Zeineldin, Albert Liu, Sumana Raychaudhuri, Ian Chiu, Jin Zhu, Barbara Smith, Nan Zhao, Peter Searson, Shigeki Watanabe, Mark Donowitz, Tatianna Chantelle Larman and Rong Li | Summary: Inflammation-associated fibroblasts (IAFs) are associated with the progression and drug resistance of chronic inflammatory […]


Continue.. Disruption of Epithelium Integrity by Inflammation-Associated Fibroblasts through Prostaglandin Signaling

Pan-viral ORFs discovery using Massively Parallel Ribosome Profiling

Kavli Affiliate: Charles M. Rice | Authors: Shira Weingarten-Gabbay, Matthew R Bauer, Alexandra C Stanton, Susan Klaeger, Eva K Verzani, Daniel Lopez, Karl R Clauser, Steven A Carr, Jennifer G Abelin, Charles M Rice and Pardis C Sabeti | Summary: Unveiling the complete proteome of viruses is crucial to our understanding of the viral life […]


Continue.. Pan-viral ORFs discovery using Massively Parallel Ribosome Profiling

Engineered bacteria launch and control an oncolytic virus

Kavli Affiliate: Charles M. Rice | Authors: Zakary S. Singer, Jonathan Pabon, Hsinyen Huang, Charles M. Rice and Tal Danino | Summary: The ability of bacteria and viruses to selectively replicate in tumors has led to synthetic engineering of new microbial therapies. Here we design a cooperative strategy whereby S. typhimurium bacteria transcribe and deliver […]


Continue.. Engineered bacteria launch and control an oncolytic virus

Advancement in Cellular Topographic and Nanoparticle Capture Imaging by High Resolution Microscopy Incorporating a Freeze-Drying and Gaseous Nitrogen-based Approach

Kavli Affiliate: Charles M. Rice | Authors: Kunihiro Uryu, Nadine Soplop, Timothy P Sheahan, Maria-Teresa Catanese, Chuong Huynh, John Pena, Nancy Boudreau, Irina Matei, Candia Kenific, Ayako Hashimoto, Ayuko Hoshino, Charles M Rice and David Lyden | Summary: Scanning electron microscopy (SEM) offers an unparalleled view of the membrane topography of mammalian cells by using […]


Continue.. Advancement in Cellular Topographic and Nanoparticle Capture Imaging by High Resolution Microscopy Incorporating a Freeze-Drying and Gaseous Nitrogen-based Approach