Bypassing spike sorting: Density-based decoding using spike localization from dense multielectrode probes

Posted by klaurent Columbia

Kavli Affiliate: Mark Churchland, Liam Paninski | Authors: Yizi Zhang, Tianxiao He, Julien Boussard, Charlie Windolf, Olivier Winter, Eric Trautmann, Noam Roth, Hailey Barrell, Mark M Churchland, Nicholas A Steinmetz, The International Brain Laboratory, Erdem Varol, Cole Hurwitz and Liam Paninski | Summary: Neural decoding and its applications to brain computer interfaces (BCI) are essential […]


Continue.. Bypassing spike sorting: Density-based decoding using spike localization from dense multielectrode probes

Placebo treatment affects brain systems related to affective and cognitive processes, but not nociceptive pain

Posted by klaurent Hopkins

Kavli Affiliate: Martin Lindquist | Authors: Rotem Botvinik-Nezer, Bogdan Petre, Marta Ceko, Martin A. Lindquist, Naomi P. Friedman and Tor D. Wager | Summary: Placebo analgesia is a replicable and well-studied phenomenon, yet it remains unclear to what degree it includes modulation of nociceptive processes. Some studies find effects consistent with nociceptive effects, but meta-analyses […]


Continue.. Placebo treatment affects brain systems related to affective and cognitive processes, but not nociceptive pain

Exploring Neural Dynamics in Self-Voice Processing and Perception: Implications for Hallucination Proneness

Posted by klaurent Hopkins

Kavli Affiliate: David Linden | Authors: Suvarnalata Xanthate Duggirala, Hanna Honcamp, Michael Schwartze, Therese Amelsvoort, Ana Pinheiro, David Linden and Sonja A Kotz | Summary: Altered sensory feedback processing and attention control are assumed to contribute to auditory verbal hallucinations, which are experienced by the general population and patients with psychosis, implying a continuum of […]


Continue.. Exploring Neural Dynamics in Self-Voice Processing and Perception: Implications for Hallucination Proneness

Single cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism

Posted by klaurent UCSF

Kavli Affiliate: Arnold R. Kriegstein | Authors: Yonatan Perez, Dmitry Velmeshev, Li Wang, Matthew White, Clara Siebert, Jennifer Baltazar, Natalia Garcia Dutton, Shaohui Wang, Maximilian Haeussler, Stormy Chamberlain and Arnold Kriegstein | Summary: Duplication 15q (dup15q) syndrome is the most common genetic cause of autism spectrum disorder (ASD). Due to a higher genetic and phenotypic […]


Continue.. Single cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism

Bering: joint cell segmentation and annotation for spatial transcriptomics with transferred graph embeddings

Posted by klaurent Hopkins

Kavli Affiliate: Jin Kang | Authors: Kang Jin, Zuobai Zhang, Ke Zhang, Francesca Viggiani, Claire Callahan, Jian Tang, Bruce J. Aronow and Jian Shu | Summary: Single-cell spatial transcriptomics such as in-situ hybridization or sequencing technologies can provide subcellular resolution that enables the identification of individual cell identities, locations, and a deep understanding of subcellular […]


Continue.. Bering: joint cell segmentation and annotation for spatial transcriptomics with transferred graph embeddings

Context-dependent hyperactivity in syngap1a and syngap1b zebrafish autism models

Posted by klaurent Hopkins

Kavli Affiliate: Richard Huganir | Authors: Sureni H. Sumathipala, Suha Khan, Robert A. Kozol, Yoichi Araki, Sheyum Syed, Richard L. Huganir and Julia Dallman | Summary: Background and Aims SYNGAP1 disorder is a prevalent genetic form of Autism Spectrum Disorder and Intellectual Disability (ASD/ID) and is caused by de novo or inherited mutations in one […]


Continue.. Context-dependent hyperactivity in syngap1a and syngap1b zebrafish autism models

Loss of cilia after neurulation impacts brain development and neuronal activity in larval zebrafish

Posted by klaurent NTNU

Kavli Affiliate: Emre Yaksi | Authors: Percival P D’Gama, Inyoung Jeong, Andreas M Nygaard, Anh-Tuan Trinh, Emre Yaksi and Nathalie Jurisch-Yaksi | Summary: Cilia are slender, hair-like structures extending from cell surfaces and playing essential roles in diverse physiological processes. Within the nervous system, primary cilia contribute to signaling and sensory perception, while motile cilia […]


Continue.. Loss of cilia after neurulation impacts brain development and neuronal activity in larval zebrafish

Dissociable roles of thalamic nuclei in the refinement of reaches to spatial targets

Posted by klaurent Columbia

Kavli Affiliate: Rui Costa | Authors: Leslie J Sibener, Alice C Mosberger, Tiffany X Chen, Vivek R Athalye, James M Murray and Rui M Costa | Summary: Reaches are complex movements that are critical for survival, and encompass the control of different aspects such as direction, speed, and endpoint precision. Complex movements have been postulated […]


Continue.. Dissociable roles of thalamic nuclei in the refinement of reaches to spatial targets

Serotonin predictively encodes value

Posted by klaurent Hopkins

Kavli Affiliate: Jeremiah Cohen | Authors: Emerson F Harkin, Cooper D Grossman, Jeremiah Y Cohen, Jean-Claude Béïque and Richard Naud | Summary: The in vivo responses of dorsal raphe nucleus (DRN) serotonin neurons to emotionally-salient stimuli are a puzzle. Existing theories centred on reward, surprise, or uncertainty individually account for some aspects of serotonergic activity […]


Continue.. Serotonin predictively encodes value

Structural basis of TRPV1 modulation by endogenous bioactive lipids

Posted by klaurent UCSF

Kavli Affiliate: Yifan Cheng | Authors: William Randall Arnold, Adamo S Mancino, Frank R Moss III, Adam Frost, David Julius and Yifan Cheng | Summary: TRP ion channels are modulated by phosphoinositide lipids, but the underlying structural mechanisms remain unclear. The capsaicin- and heat-activated receptor, TRPV1, has served as a model for deciphering lipid modulation, […]


Continue.. Structural basis of TRPV1 modulation by endogenous bioactive lipids