Structure-Function Coupling in Highly Sampled Individual Brains

Kavli Affiliate: Deanna J. Greene | Authors: Aishwarya Rajesh, Nicole A. Seider, Dillan J. Newbold, Babatunde Adeyemo, Scott Marek, Deanna J. Greene, Abraham Z Snyder, Joshua S. Shimony, Timothy O Laumann, Nico U.F. Dosenbach and Evan M. Gordon | Summary: Structural connections (SC) between distant regions of the brain support synchronized function known as functional […]


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Mice require proprioception to establish long-term visuospatial memory

Kavli Affiliate: Michael Goldberg | Authors: Michael E. Goldberg, Olivia Rutler, Randy M. Bruno, Jung Man Park, Serena Persaud, Stylianos Kosmidis and Nina Hirano | Summary: Because the retina moves constantly, the retinotopic representation of the visual world is spatially inaccurate and the brain must transform this spatially inaccurate retinal signal to a spatially accurate […]


Continue.. Mice require proprioception to establish long-term visuospatial memory

Synaptic Basis of Behavioral Timescale Plasticity

Kavli Affiliate: Franck Polleux, Attila Losonczy | Authors: Kevin C Gonzalez, Adrian Negrean, Zhenrui Liao, Franck Polleux and Attila Losonczy | Summary: Learning and memory are fundamental to adaptive behavior and cognition. Various forms of synaptic plasticity have been proposed as cellular substrates for the emergence of feature selectivity in neurons underlying episodic memory. However, […]


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Whole-cortex in situ sequencing reveals peripheral input-dependent cell type-defined area identity

Kavli Affiliate: Patrick Kanold | Authors: Xiaoyin Chen, Stephan Fischer, Mara CP Rue, Aixin Zhang, Didhiti Mukherjee, Patrick O Kanold, Jesse Gillis and Anthony Zador | Summary: The cortex is composed of neuronal types with diverse gene expression that are organized into specialized cortical areas. These areas, each with characteristic cytoarchitecture (Brodmann 1909; Vogt and […]


Continue.. Whole-cortex in situ sequencing reveals peripheral input-dependent cell type-defined area identity

Retrosplenial inputs drive diverse visual representations in the medial entorhinal cortex

Kavli Affiliate: Michael J Higley | Authors: Olivier Dubanet and Michael J. Higley | Summary: The ability of rodents to use visual cues for successful navigation and goal-directed behavior has been long appreciated, although the neural mechanisms supporting sensory representations in navigational circuits are largely unknown. Navigation is fundamentally dependent on the hippocampus and closely […]


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Fe-TAMLs as a new class of small molecule peroxidase probes for correlated light and electron microscopy

Kavli Affiliate: Mark Ellisman | Authors: Stephen R Adams, Mason R Mackey, Ranjan Ramachandra, Thomas J Deerinck, Guillaume A Castillon, Sebastien Phan, Junru Hu, Daniela Boassa, John T Ngo and Mark H Ellisman | Summary: We introduce Fe-TAML, a small molecule-based peroxidase as a versatile new member of the correlated fluorescence and electron microscopy toolkit. […]


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Decoding transcriptomic signatures of Cysteine String Protein alpha-mediated synapse maintenance

Kavli Affiliate: Sreeganga Chandra | Authors: Na Wang, Biqing Zhu, Mary Alice Allnutt, Rosalie M Grijalva, Hongyu Zhao and Sreeganga S Chandra | Summary: Synapse maintenance is essential for generating functional circuitry and decrement in this process is a hallmark of neurodegenerative disease. While we are beginning to understand the basis of synapse formation, much […]


Continue.. Decoding transcriptomic signatures of Cysteine String Protein alpha-mediated synapse maintenance

Scaling use of the rust fungus Puccinia punctiformis for biological control of Canada thistle (Cirsium arvense (L.) Scop.): First report on a U.S. statewide effort

Kavli Affiliate: Robert E. Clark | Authors: Dan W. Bean, Kristi Gladem, Karen Rosen, Alexander Blake, Robert E. Clark, Caitlin Henderson, John Kaltenbach, Joel Price, Emily L. Smallwood, Dana K. Berner, Stephen L. Young and Robert N. Schaeffer | Summary: Canada thistle (Cirsium arvense (L.) Scop., CT) is one of the worst weeds threatening temperate […]


Continue.. Scaling use of the rust fungus Puccinia punctiformis for biological control of Canada thistle (Cirsium arvense (L.) Scop.): First report on a U.S. statewide effort

MAP1B Regulates Cortical Neuron Interstitial Axon Branching Through the Tubulin Tyrosination Cycle

Kavli Affiliate: Alex Kolodkin | Authors: Jakub Ziak, Joelle Dorskind, Brian Trigg, Sriram Sudarsanam, Randal Hand and Alex L Kolodkin | Summary: Regulation of directed axon guidance and branching during development is essential for the generation of neuronal networks. However, the molecular mechanisms that underlie interstitial axon branching in the mammalian brain remain unresolved. Here, […]


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Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing

Kavli Affiliate: Liam Paninski | Authors: Marcus A. Triplett, Marta Gajowa, Benjamin Antin, Masato Sadahiro, Hillel Adesnik and Liam Paninski | Summary: Abstract Discovering how neural computations are implemented in the cortex at the level of monosynaptic connectivity requires probing for the existence of synapses from possibly thousands of presynaptic candidate neurons. Two-photon optogenetics has […]


Continue.. Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing