Multicore fiber optic imaging reveals that astrocyte calcium activity in the cerebral cortex is modulated by internal motivational state

Posted by klaurent Hopkins

Kavli Affiliate: Jin Kang, Dwight Bergles | Authors: Yung-Tian A. Gau, Eric Hsu, Jaepyeong Cha, Rebecca W. Pak, Loren L. Looger, Jin U. Kang and Dwight E. Bergles | Summary: Astrocytes are a direct target of neuromodulators and can influence neuronal activity on broad spatial and temporal scales through their close proximity to synapses. However, […]


Continue.. Multicore fiber optic imaging reveals that astrocyte calcium activity in the cerebral cortex is modulated by internal motivational state

Neural dynamics and geometry for transitive inference

Posted by klaurent Columbia

Kavli Affiliate: Vincent Ferrera, Daphna Shohamy, Larry Abbott | Authors: Kenneth Kay, Natalie Biderman, Ramin Khajeh, Manuel Beiran, Christopher J Cueva, Daphna Shohamy, Greg Jensen, Xue-Xin Wei, Vincent P Ferrera and L F Abbott | Summary: Relational cognition — the ability to infer relationships that generalize to novel combinations of objects — is fundamental to […]


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RNA- and ATAC-sequencing Reveals a Unique CD83+ Microglial Population Focally Depleted in Parkinson’s Disease

Posted by klaurent Columbia

Kavli Affiliate: Rui Costa | Authors: Zena K Chatila, Archana Yadav, Jason Mares, Xena E Flowers, Taekyung D Yun, Mamunur Rashid, Ryan Talcoff, Zoe Pelly, Ya Zhang, Philip L De Jager, Andrew F Teich, Rui M Costa, Estela Area Gomez, Gabriela J Martins, Roy N Alcalay, Jean Paul Vonsattel, Vilas Menon, Elizabeth M Bradshaw and […]


Continue.. RNA- and ATAC-sequencing Reveals a Unique CD83+ Microglial Population Focally Depleted in Parkinson’s Disease

The emergence of human gastrulation upon in vitro attachment

Posted by klaurent Rockefeller

Kavli Affiliate: Ali H. Brivanlou | Authors: Riccardo De Santis, Eleni Rice, Gist Croft, Min Yang, Edwin A. Rosado-Olivieri and Ali H. Brivanlou | Summary: While studied extensively in model systems, human gastrulation remains obscure. This process starts upon blastocyst implantation into the uterine wall, which is assumed to occur after 14 days post-fertilization. The […]


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Towards the biogeography of butyrate-producing bacteria

Posted by klaurent UCSF

Kavli Affiliate: Robert Edwards | Authors: Joel E Brame, Craig Liddicoat, Catherine A Abbott, Robert A Edwards, Jake M Robinson, Nicolas E Gauthier and Martin F Breed | Summary: Butyrate-producing bacteria are found in many ecosystems and organisms, including humans, and are vital to ecosystem functionality and human health. These bacteria ferment organic matter, producing […]


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Sex chromosome gene expression associated with vocal learning following hormonal manipulation in female zebra finches

Posted by klaurent Rockefeller

Kavli Affiliate: Erich Jarvis | Authors: Matthew Davenport, Ha Na Choe, Hiroaki Matsunami and Erich D Jarvis | Summary: Zebra finches are sexually dimorphic vocal learners. Males learn to sing by imitating mature conspecifics, but females do not. Absence of song in females is associated with atrophy and apparent repression of several vocal learning brain […]


Continue.. Sex chromosome gene expression associated with vocal learning following hormonal manipulation in female zebra finches

Invariant neural dynamics drive commands to control different movements

Posted by klaurent Columbia

Kavli Affiliate: Rui Costa | Authors: Vivek Ravindra Athalye, Preeya Khanna, Suraj Gowda, Amy L Orsborn, Rui M Costa and Jose M Carmena | Summary: It has been proposed that the nervous system has the capacity to generate a wide variety of movements because it re-uses some invariant code. Previous work has identified that dynamics […]


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Social experiences shape song preference learning independent of developmental exposure to song

Posted by klaurent Columbia

Kavli Affiliate: Sarah Woolley | Authors: Erin Mckenzie Wall and Sarah Cushing Woolley | Summary: Communication governs the formation and maintenance of social relationships. The interpretation of communication signals depends not only on the signal’s content, but also on a receiver’s individual experience. Experiences throughout life may interact to affect behavioral plasticity, such that a […]


Continue.. Social experiences shape song preference learning independent of developmental exposure to song

Allosteric regulation of TRPV1 by the inflammatory lipid, LPA

Posted by klaurent UCSF

Kavli Affiliate: Yifan Cheng | Authors: William Randall Arnold, David Julius and Yifan Cheng | Summary: Transient Receptor Potential Vanilloid 1 (TRPV1) is a tetrameric cation channel expressed in primary afferent neurons, where it contributes to thermosensation and nociception. TRPV1 is a polymodal signal integrator that responds not only to heat, but also to inflammatory […]


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Reward contingency gates selective cholinergic suppression of amygdala neurons

Posted by klaurent UCSD / Salk

Kavli Affiliate: Kay Tye | Authors: Eyal Y. Kimchi, Anthony Burgos-Robles, Gillian A Matthews, Tatenda Chakoma, Makenzie Patarino, Javier C Weddington, Cody A Siciliano, Wannan Yang, Shaun Foutch, Renee Simons, Ming-fai Fong, miao jing, Yulong Li, Daniel B Polley and Kay M. Tye | Summary: Basal forebrain cholinergic neurons modulate how organisms process and respond […]


Continue.. Reward contingency gates selective cholinergic suppression of amygdala neurons