Kavli Affiliate: Michael Beer | Authors: Hira Jabeen, Michael Beer, James Spencer, Marc W van der Kamp, H Adrian Bunzel and Adrian J Mulholland | Summary: MAntimicrobial resistance is a public health crisis. Limited understanding of the catalytic drivers in resistance-mediating enzymes such as β-lactamases hinders our ability to combat this crisis. Here, we dissect […]
Kavli Affiliate: Vanessa Ruta | Authors: Tom Hindmarsh Sten, Rufei Li, Florian Hollunder, Shadé Eleazer and Vanessa Ruta | Summary: Males of many species have evolved behavioral traits to both attract females and repel rivals. Here, we explore mate selection in Drosophila from both the male and female perspective to shed light on how these […]
Kavli Affiliate: Denis Wirtz | Authors: Jeanette A.I. Johnson, Genevieve L Stein-O’Brien, Max Booth, Randy Heiland, Furkan Kurtoglu, Daniel Bergman, Elmar Bucher, Atul Deshpande, Andre Forjaz, Michael Getz, Ines Godet, Melissa Lyman, John Metzcar, Jacob Mitchell, Andrew Raddatz, Heber L. Rocha, Jacobo Solorzano, Aneequa Sundus, Yafei Wang, Daniele M. Gilkes, Luciane T. Kagohara, Ashley L. […]
Kavli Affiliate: Seth Blackshaw | Authors: Nguyet Le, Trieu-Duc Vu, Isabella Palazzo, Ritvik Pulya, Yehna Kim, Seth Blackshaw and Thanh Hoang | Summary: Neurogenic competence is actively repressed in mature mammalian Muller glial cells, and previous studies have predicted that this is in part mediated by active Notch signaling. To determine whether global loss of […]
Kavli Affiliate: Jeremias Sulam | Authors: Helge J Zollner, Christopher B. Davies-Jenkins, Dunja B. Simicic, Assaf Tal, Jeremias Sulam and Georg Oeltzschner | Summary: Purpose: The interest in application and modeling of dynamic MRS has recently grown. Therefore, it is imperative to systematically investigate accuracy, precision, and uncertainty estimation of 2D modeling algorithms. 2D modeling […]
Kavli Affiliate: Menno Witter and Maximiliano Jose Nigro | Authors: Erik J Courcelles, Kasper Kjelsberg, Laura Convertino, Rajeevkumar Raveendran Nair, Menno P Witter and Maximiliano J Nigro | Summary: GABAergic neurons represent 10-15% of the neuronal population of the cortex but exert a powerful control over information flow in cortical circuits. The largest GABAergic class […]
Kavli Affiliate: Martin Lindquist | Authors: Brent William Stewart, Michael L Keaser, Hwiyoung Lee, Sarah M Margerison, Matthew A Cormie, Massieh Moayedi, Martin Lindquist, Shuo Chen, Brian N. Mathur and David A Seminowicz | Summary: Aberrant cognitive network activity and cognitive deficits are established features of chronic pain. However, the nature of cognitive network alterations […]
Kavli Affiliate: Michael Shadlen, Liam Paninski, Mark Churchland, & Edward Chang | Authors: Charlie Windolf, Han Yu, Angelique C. Paulk, Domokos Meszéna, William Muñoz, Julien Boussard, Richard Hardstone, Irene Caprara, Mohsen Jamali, Yoav Kfir, Duo Xu, Jason E. Chung, Kristin K. Sellers, Zhiwen Ye, Jordan Shaker, Anna Lebedeva, Manu Raghavan, Eric Trautmann, Maxwell D. Melin, […]
Kavli Affiliate: Jin Kang | Authors: Brian J Bender, Julie E Pickett, Joao Braz, Hye Jin Kang, Stefan Gahbauer, Karnika Bhardwaj, Sian Rodriguez-Rosado, Yongfeng Liu, Manish Jain, Allan Basbaum, Bryan L Roth and Brian K. Shoichet | Summary: While opioid drugs remain among the most effective analgesics for pain management, adverse effects limit their use. […]
Kavli Affiliate: Alex Kolodkin | Authors: Noelle Thielman, Vanessa Funes, Sanjana Davuluri, Hector lbanez, Wei-Chih Sun, Juan Fu, Keyu Li, Stephen Muth, Xingyi Pan, Kenji Fujiwara, Dwayne Thomas, MacKenzie Henderson, Selina Shiqing Teh, Qingfeng Zhu, Elizabeth Thompson, Elizabeth M Jaffee, Alex Kolodkin, Fengxi Meng and Lei Zheng | Summary: Axon guidance molecules were found to […]