Three-dimensional assessments are necessary to determine the true spatial tissue composition of diseased tissues

Posted by dbos Hopkins

Kavli Affiliate: Denis Wirtz | Authors: André Forjaz, Eduarda Vaz, Valentina Matos Romero, Saurabh Joshi, Alicia M. Braxton, Ann C. Jiang, Kohei Fujikura, Toby Cornish, Seung-Mo Hong, Ralph H. Hruban, Pei-Hsun Wu, Laura D. Wood, Ashley L. Kiemen and Denis Wirtz | Summary: Methods for partially resolved cellular profiling has enabled in-depth quantitative tissue mapping […]


Continue.. Three-dimensional assessments are necessary to determine the true spatial tissue composition of diseased tissues

A reference genome for the Andean cavefish Trichomycterus rosablanca (Siluriformes, Trichomycteridae): building genomic resources to study evolution in cave environments

Posted by dbos Rockefeller

Kavli Affiliate: Erich Jarvis | Authors: Daniel Cadena, Laura Pabon, Carlos DoNascimiento, Linelle Abueg, Tatiana Tiley, Brian O-Toole, Dominic Absolon, Ying Sims, Giulio Formenti, Olivier Fedrigo, Erich Jarvis and Mauricio Torres | Summary: Animals living in caves are of broad relevance to evolutionary biologists interested in understanding the mechanisms underpinning convergent evolution. In the Eastern […]


Continue.. A reference genome for the Andean cavefish Trichomycterus rosablanca (Siluriformes, Trichomycteridae): building genomic resources to study evolution in cave environments

Glia detect and mount a protective response to loss of dendrite substructure integrity in C. elegans

Posted by dbos Rockefeller

Kavli Affiliate: Shai Shaham | Authors: Colin W Hoy, Coralie de Hemptinne, Sarah S Wang, Catherine J Harmer, Matthew A J Apps, Masud Husain, Philip A Starr and Simon Little | Summary: Neurons have elaborate structures that determine their connectivity and functions. Changes in neuronal structure accompany learning and memory formation and are hallmarks of […]


Continue.. Glia detect and mount a protective response to loss of dendrite substructure integrity in C. elegans

A Photoactivatable Norepinephrine for Probing Adrenergic Neural Circuits

Posted by dbos UCSF

Kavli Affiliate: Kira Poskanzer | Authors: Michelle K. Cahill, Yeraldith Rojas Perez, Amara Larpthaveesarp, Roberto Etchenique and Kira E Poskanzer | Summary: Norepinephrine (NE) is a critical neuromodulator that mediates a wide range of behavior and neurophysiology, including attention, arousal, plasticity, and memory consolidation. A major source of NE is the brainstem nucleus the locus […]


Continue.. A Photoactivatable Norepinephrine for Probing Adrenergic Neural Circuits

Engineered Secretory Immunoglobulin A provides insights on antibody-based effector mechanisms targeting Clostridiodes difficile

Posted by dbos Hopkins

Kavli Affiliate: Michael Miller | Authors: Sonya Kumar Bharathkar, Michael J. Miller and Beth M. Stadtmueller | Summary: Secretory (S) Immunoglobin (Ig) A is the predominant mucosal antibody, which mediates host interactions with commensal and pathogenic microbes, including Clostridioides difficile. SIgA adopts a polymeric IgA structure that is bound by secretory component (SC). Despite significance, […]


Continue.. Engineered Secretory Immunoglobulin A provides insights on antibody-based effector mechanisms targeting Clostridiodes difficile

An encyclopedia of enhancer-gene regulatory interactions in the human genome

Posted by dbos Hopkins

Kavli Affiliate: Michael Beer | Authors: Andreas R. Gschwind, Kristy S. Mualim, Alireza Karbalayghareh, Maya U. Sheth, Kushal K. Dey, Evelyn Jagoda, Ramil N. Nurtdinov, Wang Xi, Anthony S. Tan, Hank Jones, X. Rosa Ma, David Yao, Joseph Nasser, Ziga Avsec, Benjamin T. James, Muhammad S. Shamim, Neva C. Durand, Suhas S. P. Rao, Ragini […]


Continue.. An encyclopedia of enhancer-gene regulatory interactions in the human genome

Investigating egocentric tuning in hippocampal CA1 neurons using simulated data

Posted by dbos NTNU

Kavli Affiliate: Edvard Moser & May-Britt Moser | Authors: Jordan Carpenter, Jan Sigurd Blackstad, David Tingley, Valentin A. Normand, Edvard I. Moser, May-Britt Moser and Benjamin A. Dunn | Summary: Navigation requires integrating sensory information with a stable schema to create a dynamic map of an animal’s position using egocentric and allocentric coordinate systems. In […]


Continue.. Investigating egocentric tuning in hippocampal CA1 neurons using simulated data

Microbiota-dependent early life programming of gastrointestinal motility

Posted by dbos Hopkins

Kavli Affiliate: David Linden | Authors: Mary E Frith, Purna C Kashyap, David R Linden, Betty Theriault and Eugene B Chang | Summary: Gastrointestinal microbes modulate peristalsis and stimulate the enteric nervous system (ENS), whose development, as in the central nervous system (CNS), continues into the murine postweaning period. Given that adult CNS function depends […]


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Ammonia-oxidizing archaea and bacteria differentially contribute to ammonia oxidation in soil under precipitation gradients and land legacy

Posted by dbos Rockefeller

Kavli Affiliate: Charles M. Rice | Authors: Soumyadev Sarkar, Anna Kazarina, Paige M. Hansen, Kaitlyn Ward, Christopher Hargreaves, Nicholas Reese, Qinghong Ran, Willow Kessler, Ligia F.T. de Souza, Terry D. Loecke, Marcos V.M. Sarto, Charles W. Rice, Lydia H. Zeglin, Benjamin A. Sikes and Sonny T.M. Lee | Summary: Global change has accelerated the nitrogen […]


Continue.. Ammonia-oxidizing archaea and bacteria differentially contribute to ammonia oxidation in soil under precipitation gradients and land legacy

Abstract representations emerge in human hippocampal neurons during inference behavior

Posted by dbos Columbia

Kavli Affiliate: Stefano Fusi & Daniel Salzman | Authors: Hristos Spiridonos Courellis, Juri Minxha, Araceli Ramirez Cardenas, Daniel L Kimmel, Chrystal M Reed, Taufik A Valiante, C. Daniel Salzman, Adam N Mamelak, Ralph Adolphs, Stefano Fusi and Ueli Rutishauser | Summary: Humans have the remarkable cognitive capacity to rapidly adapt to changing environments. Central to […]


Continue.. Abstract representations emerge in human hippocampal neurons during inference behavior