Estrus-Tracking Cortical Neurons Integrate Social cues and Reproductive states to Adaptively Control Sexually Dimorphic Sociosexual Behaviors

Posted by dbos Rockefeller

Kavli Affiliate: Nathaniel Heintz | Authors: Yuping Wang, Xinli Song, Xiangmao Chen, Ying Zhou, Jihao Ma, Fang Zhang, Liqiang Wei, Guoxu Qi, Nakul Yadav, Benjie Miao, Yiming Yan, Guohua Yuan, Da Mi, Priyamvada Rajasethupathy, Ines Ibanez-Tallon, Xiaoxuan Jia, Nathaniel Heintz and Kun Li | Summary: Female sociosexual behaviors, essential for survival and reproduction, are adaptively […]


Continue.. Estrus-Tracking Cortical Neurons Integrate Social cues and Reproductive states to Adaptively Control Sexually Dimorphic Sociosexual Behaviors

Brain Charts for the Rhesus Macaque Lifespan

Posted by dbos Rockefeller

Kavli Affiliate: Winrich Freiwald | Authors: Samuel Alldritt, Julian S.B. Ramirez, Reinder Vos de Wael, Richard Bethlehem, Jakob Seidlitz, Zexi Wang, Karl-Heinz Nenning, Nathalia B. Esper, Jonathan Smallwood, Alexandre R. Franco, Kyoungseob Byeon, Aaron Alexander-Bloch, Adam Messinger, Aihua Chen, Alexander Thiele, Alison R. Weiss, Amir Shmuel, Andrew Fox, Anita Tusche, Ansgar M. Brambrink, Arnaud Falchier, […]


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A Hybrid Type I and II Polyketide Synthases Yields Distinct Aromatic Polyketides

Posted by dbos Rockefeller

Kavli Affiliate: Li Zhao | Authors: Li Ya Zhao, Jing Shi, Zhao Yang Xu, Jia Lin Sun, Zhang Yuan Yan, Zhi Wu Tong, Ren Xiang Tan, Rui Hua Jiao and Hui Ming Ge | Summary: Bacterial aromatic polyketides are compounds with multiple aromatic rings synthesized by bacterial type II polyketide synthases (PKSs), some of which […]


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De novo-designed minibinders expand the synthetic biology sensing repertoire

Posted by dbos UCSF

Kavli Affiliate: Hana El-Samad | Authors: Zara Y. Weinberg, Sarah S. Soliman, Matthew S. Kim, Irene P. Chen, Melanie Ott and Hana El-Samad | Summary: Synthetic and chimeric receptors capable of recognizing and responding to user-defined antigens have enabled “smart” therapeutics based on engineered cells. These cell engineering tools depend on antigen sensors which are […]


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Polyunsaturated fatty acid-derived lipid mediator networks characterize COVID-19 severity and risk for critical illness

Posted by dbos Rockefeller

Kavli Affiliate: Martin Lindquist | Authors: Maria Papadaki, Eleftherios Pavlos, Marc Dubourdeau, Vincent Bailif, Kamal Badirou, Ioanna-Evdokia Galani, Dimitris Papelis, Natalia Kamperi, Vasiliki Triantafyllia, Lena Siouti, Maria Salagianni, Maria Manioudaki, Nikolaos Paschalidis, Giannis Vatsellas, Evangelia Koukaki, Vasiliki Rapti, Dimitris Thanos, Nikoletta Rovina, Garyfallia Poulakou, Aurelie Cobat, Jean-Laurent Casanova, Constantin Tamvakopoulos and Evangelos Andreakos | Summary: […]


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Effects of connectivity hyperalignment (CHA) on estimated brain network properties: from coarse-scale to fine-scale

Posted by dbos Hopkins

Kavli Affiliate: Martin Lindquist | Authors: Farzad V. Farahani, Mary Beth Nebel, Tor Wager and Martin A. Lindquist | Summary: Recent gains in functional magnetic resonance imaging (fMRI) studies have been driven by increasingly sophisticated statistical and computational techniques and the ability to capture brain data at finer spatial and temporal resolution. These advances allow […]


Continue.. Effects of connectivity hyperalignment (CHA) on estimated brain network properties: from coarse-scale to fine-scale

Using artificial intelligence to document the hidden RNA virosphere

Posted by dbos Rockefeller

Kavli Affiliate: Li Zhao | Authors: Xin Hou, Yong He, Pan Fang, Shi-Qiang Mei, Zan Xu, Wei-Chen Wu, Jun-Hua Tian, Shun Zhang, Zhen-Yu Zeng, Qin-Yu Gou, Gen-Yang Xin, Shi-Jia Le, Yin-Yue Xia, Yu-Lan Zhou, Feng-Ming Hui, Yuan-Fei Pan, John-Sebastian Eden, Zhao-Hui Yang, Chong Han, Yue-Long Shu, Deyin Guo, Jun Li, Edward C Holmes, Zhao-Rong Li […]


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HMGB1 restores a dynamic chromatin environment in the presence of linker histone by deforming nucleosomal DNA

Posted by dbos UCSF

Kavli Affiliate: Yifan Cheng | Authors: Hayden S Saunders, Un Seng Chio, Camille M Moore, Vijay Ramani, Yifan Cheng and Geeta Narlikar | Summary: Summary: The essential architectural protein HMGB1 increases accessibility of nucleosomal DNA and counteracts the effects of linker histone H1. However, HMGB1 is less abundant than H1 and binds nucleosomes more weakly […]


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The applicability of Regional Red List assessments for soil invertebrates: First assessment of five native earthworm species in Canada

Posted by dbos UCSD / Salk

Kavli Affiliate: John Reynolds | Authors: Helen R P Phillips, George Gardner Brown, Sam W. James, Jérôme Mathieu, John Warren Reynolds, Maheshi E Dharmasiri, Claire L. Singer, Maria J. I. Briones, Heather C. Procter and Erin K. Cameron | Summary: Summary: Earthworms (Annelida: Clitellata: Crassiclitellata) are prominent members of the soil community, important to many […]


Continue.. The applicability of Regional Red List assessments for soil invertebrates: First assessment of five native earthworm species in Canada

Solving the “Blind men and the elephant problem”: Additive deep learning of complex high dimensional models from partial faceted datasets

Posted by dbos Hopkins

Kavli Affiliate: Denis Wirtz | Authors: Yufei Wu, Pei-Hsun Wu, Allison Chambliss, Denis Wirtz and Sean Sun | Summary: Summary: Biological systems are complex networks involving tens of thousands of interacting molecular components, and measurable biological functions are emerging properties of these complex networks. Many quantitative studies in biology attempt to connect biological function with […]


Continue.. Solving the “Blind men and the elephant problem”: Additive deep learning of complex high dimensional models from partial faceted datasets