Kavli Affiliate: Robert Edwards | Authors: Bhavya Papudeshi, Michael J. Roach, Vijini Mallawaarachchi, George Bouras, Susanna R Grigson, Sarah K Giles, Clarice M Harker, Abbey L.K Hutton, Anita Tarasenko, Laura K Inglis, Alejandro A Vega, Cole Souza, Lance Boling, Hamza Hajama, Ana Georgina Cobian-Guemes, Anca Segall, Elizabeth A Dinsdale and Robert A Edwards | Summary: […]
Kavli Affiliate: Liam Paninski | Authors: Charles Findling, Felix Hubert, International Brain Laboratory, Luigi Acerbi, Brandon Benson, Julius Benson, Daniel Birman, Niccolò Bonacchi, Matteo Carandini, Joana A Catarino, Gaelle A Chapuis, Anne K Churchland, Yang Dan, Eric EJ DeWitt, Tatiana A Engel, Michele Fabbri, Mayo Faulkner, Ila Rani Fiete, Laura Freitas-Silva, Berk Gerçek, Kenneth D […]
Kavli Affiliate: Robert B. Darnell | Authors: Krithi Irmady, Claudia Scheckel, Ruth A Singer, Thomas Carroll and Robert B Darnell | Summary: The neuronal RNA-binding protein (RBP) family nELAVL regulates key neuronal processes by binding directly to target RNA transcripts. In this study, we demonstrate that ELAVL3 is the predominant nELAVL paralog expressed in D1 […]
Kavli Affiliate: Massimo Scanziani | Authors: Guy Bouvier, Alessandro Sanzeni, Elizabeth Hamada, Nicolas Brunel and Massimo Scanziani | Summary: Head movements are sensed by the vestibular organs. Unlike classical senses, signals from vestibular organs are not conveyed to a dedicated cortical area but are broadcast throughout the cortex. Surprisingly, the routes taken by vestibular signals […]
Kavli Affiliate: Eric D. Siggia | Authors: Stefano Fusi and Liam Paninski | Summary: The brain is highly structured both at anatomical and functional levels. However, within individual brain areas, neurons often exhibit very diverse and seemingly disorganized responses. A more careful analysis shows that these neurons can sometimes be grouped together into specialized subpopulations […]
Kavli Affiliate: Eric D. Siggia | Authors: Ismail Hajji, Eric D Siggia, Francis Corson and Wolfgang Keil | Summary: During development, cells gradually assume specialized fates via changes of transcriptional dynamics in thousands of genes. Terminal cell identities are then stabilized through the convergence of gene regulatory network dynamics and the accumulation of epigenetic DNA […]
Kavli Affiliate: Adam Gazzaley | Authors: Lorenzo Pasquini, Jakub Vohryzek, Anira Escrichs, Yonatan Sanz Perl, Adrian Ponce-Alvarez, Sebastian Idesis, Manesh Girn, Leor Roseman, Jennifer M Mitchell, Adam Gazzaley, Morten Kringelbach, David J Nutt, Taylor Lyons, Robin L Carhart-Harris and Gustavo Deco | Summary: Psilocybin has been shown to induce fast and sustained improvements in mental […]
Kavli Affiliate: Alex Pollen | Authors: Sara Nolbrant, Jenelle L. Wallace, Jingwen Ding, Tianjia Zhu, Jess L. Sevetson, Janko Kajtez, Isabella A. Baldacci, Emily K. Corrigan, Kaylynn Hoglin, Reed McMullen, Matthew T. Schmitz, Arnar Breevoort, Dani Swope, Fengxia Wu, Bryan J. Pavlovic, Sofie R. Salama, Agnete Kirkeby, Hao Huang, Nathan K. Schaefer and Alex A. […]
Kavli Affiliate: Gabriel Silva | Authors: Jeziel D Damasceno, Gabriel LA Silva, Catarina A Marques, Marija Krasilnikova, Craig Lapsley, Dario Beraldi and Richard McCulloch | Summary: Understanding genome duplication requires characterisation of the locations where DNA replication initiates, termed origins. Genome-wide mapping of DNA replication origins has mainly been derived from population-based techniques, with only […]
Kavli Affiliate: Ann McDermott | Authors: Cassandra A Chartier, Virgil A Woods, Yunyao Xu, Anne E van Vlimmeren, Marko Jovanovic, Ann E McDermott, Daniel A Keedy and Neel H Shah | Summary: The rapid identification of protein-protein interactions has been significantly enabled by mass spectrometry (MS) proteomics-based methods, including affinity purification-MS, crosslinking-MS, and proximity-labeling proteomics. […]