Subcellular niche segregation of co-obligate symbionts in whiteflies

Kavli Affiliate: Ying Meng | Authors: Akiko FUJIWARA, Xian-Ying Meng, Yoichi Kamagata and Tsutomu TSUCHIDA | Summary: Abstract Many insects contain endosymbiotic bacteria within their bodies. In multiple endosymbiotic systems comprising two or more symbionts, each of the symbionts is generally localized in a different host cell or tissue. Bemisia tabaci (Sweet potato whitefly)possesses a […]


Continue.. Subcellular niche segregation of co-obligate symbionts in whiteflies

Quadratic computations maintain neural specificity to natural stimuli across stages of visual processing

Kavli Affiliate: Tatyana Sharpee | Authors: Ryan J. Rowekamp and Tatyana Sharpee | Summary: Abstract Despite recent successes in machine vision, artificial recognition systems continue to be less robust than biological systems. The brittleness of artificial recognition system has been attributed to the linearity of the core operation that matches inputs to target patterns at […]


Continue.. Quadratic computations maintain neural specificity to natural stimuli across stages of visual processing

Divergent impacts of C9orf72 repeat expansion on neurons and glia in ALS and FTD

Kavli Affiliate: Eran Mukamel | Authors: Junhao Li, Manoj K Jaiswal, Jo-Fan Chien, Alexey Kozlenkov, Ping Zhou, Mahammad Gardashli, Luc J Pregent, Erica Engelberg-Cook, Dennis W Dickson, Veronique V Belzil, Eran A Mukamel and Stella Dracheva | Summary: Abstract Neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), are strongly influenced by […]


Continue.. Divergent impacts of C9orf72 repeat expansion on neurons and glia in ALS and FTD

Identifying genes and pathways linking astrocyte regional specificity to Alzheimer’s disease susceptibility

Kavli Affiliate: Paul Greengard | Authors: Ran Zhang, Margarete Knudsen, Pedro Del Cioppo Vasques, Alicja Tadych, Patricia Rodriguez-Rodriguez, Paul Greengard, Jean-Pierre Roussarie, Ana Milosevic and Olga G. Troyanskaya | Summary: Abstract Astrocytes have been shown to play a central role in Alzheimer’s Disease (AD). However, the genes and biological pathways underlying disease manifestation are unknown, […]


Continue.. Identifying genes and pathways linking astrocyte regional specificity to Alzheimer’s disease susceptibility

An open-access EEG dataset for speech decoding: Exploring the role of articulation and coarticulation

Kavli Affiliate: Terrence Sejnowski | Authors: João Pedro Carvalho Moriera, Vinícius Rezende Carvalho, Eduardo Mazoni Andrade Marçal Mendes, Aria Fallah, Terrence J. Sejnowski, Claudia Lainscsek and Lindy B Comstock | Summary: Abstract Electroencephalography (EEG) holds promise for brain-computer interface (BCI) devices as a non-invasive measure of neural activity. With increased attention to EEG-based BCI systems, […]


Continue.. An open-access EEG dataset for speech decoding: Exploring the role of articulation and coarticulation

Tumor proliferation and invasion are coupled through cell-extracellular matrix friction

Kavli Affiliate: Denis Wirtz | Authors: Ashleigh J. Crawford, Clara Gomez-Cruz, Gabriella C. Russo, Wilson Huang, Isha Bhorkar, Arrate Munoz-Barrutia, Denis Wirtz and Daniel Garcia-Gonzalez | Summary: Abstract Cell proliferation and invasion are two key drivers of tumor progression and are traditionally considered two independent cellular processes regulated by distinct pathways. Through in vitro and […]


Continue.. Tumor proliferation and invasion are coupled through cell-extracellular matrix friction

A method of inferring partially observable Markov models from syllable sequences reveals the effects of deafening on Bengalese finch song syntax

Kavli Affiliate: Kristofer Bouchard | Authors: Jiali Lu, Sumithra Surendralal, Kristofer E Bouchard and Dezhe Z. Jin | Summary: Abstract Songs of the Bengalese finch consist of variable sequences of syllables. The sequences follow probabilistic rules, and can be statistically described by partially observable Markov models (POMMs), which consist of states and probabilistic transitions between […]


Continue.. A method of inferring partially observable Markov models from syllable sequences reveals the effects of deafening on Bengalese finch song syntax

Direct Cortical Inputs to Hippocampal Area CA1 Transmit Complementary Signals for Goal-directed Navigation

Kavli Affiliate: Attila Losonczy | Authors: John C Bowler and Attila Losonczy | Summary: Summary The entorhinal cortex (EC) is central to the brain’s navigation system. Its subregions are conventionally thought to compute dichotomous representations for spatial processing: medial entorhinal cortex (MEC) provides a global spatial map, while lateral entorhinal cortex (LEC) encodes specific sensory […]


Continue.. Direct Cortical Inputs to Hippocampal Area CA1 Transmit Complementary Signals for Goal-directed Navigation

The HCN1 hyperpolarization-activated cyclic nucleotide-gated channel enhances evoked GABA release from parvalbumin positive interneurons

Kavli Affiliate: Steven Siegelbaum | Authors: Tobias Bock, Eric W Buss, Olivia M Lofaro, Felix W Leroy, Bina Santoro and Steven A Siegelbaum | Summary: Abstract Hyperpolarization-activated, cyclic nucleotide-gated (HCN) channels generate the cationic Ih current in neurons and regulate the excitability of neuronal networks. The function of HCN channels depends, in part, on their […]


Continue.. The HCN1 hyperpolarization-activated cyclic nucleotide-gated channel enhances evoked GABA release from parvalbumin positive interneurons

Converting an allocentric goal into an egocentric steering signal

Kavli Affiliate: Gaby Maimon | Authors: Peter Mussells Pires, L F Abbott and Gaby Maimon | Summary: Abstract Neuronal signals relevant for spatial navigation have been described in many species[1-12], however, a circuit-level understanding of how such signals interact to guide behaviour is lacking. Here we characterize a neuronal circuit in the Drosophila central complex […]


Continue.. Converting an allocentric goal into an egocentric steering signal