A Real-time Multi-Subject Three Dimensional Pose Tracking System for Analyzing Social Behaviors of Non-human Primates

Kavli Affiliate: Xiaoqin Wang | Authors: Chaoqun Cheng, Zijian Huang, Ruiming Zhang, Guozheng Huang, Han Wang, Likai Tang and Xiaoqin Wang | Summary: Summary: The ability to track positions and poses (body parts) of multiple monkeys in a 3D space in real time is highly desired by non-human primate (NHP) researchers in behavioral and systems […]


Continue.. A Real-time Multi-Subject Three Dimensional Pose Tracking System for Analyzing Social Behaviors of Non-human Primates

Functional Regrowth of Norepinephrine Axons in the Adult Mouse Brain Following Injury

Kavli Affiliate: David Linden | Authors: Patrick R Cooke and David J Linden | Summary: Summary: It is widely believed that axons in the central nervous system of adult mammals do not regrow following injury. This failure is thought, at least in part, to underlie the limited recovery of function following injury to the brain […]


Continue.. Functional Regrowth of Norepinephrine Axons in the Adult Mouse Brain Following Injury

CellCover Captures Neural Stem Cell Progression in Mammalian Neocortical Development

Kavli Affiliate: Jean Fan and Laurent Younes | Authors: Lanlan Ji, An Wang, Shreyash Sonthalia, Daniel Q Naiman, Laurent Younes, Carlo Colantuoni and Donald Geman | Summary: Summary: Definition of cell classes across the tissues of living organisms is central in the analysis of growing atlases of single-cell RNA sequencing (scRNA-seq) data across biomedicine. Marker […]


Continue.. CellCover Captures Neural Stem Cell Progression in Mammalian Neocortical Development

CellCover Defines Temporal Progression in Conserved Cell Types and Informs oRG Evolution using scRNA-seq Data in Mammalian Neocortical Development

Kavli Affiliate: Donald Geman and Laurent Younes | Authors: Lanlan Ji, An Wang, Shreyash Sonthalia, Daniel Q Naiman, Laurent Younes, Carlo Colantuoni and Donald Geman | Summary: Accurate identification of cell classes across the tissues of living organisms is central in the analysis of growing atlases of single-cell RNA sequencing (scRNA-seq) data across biomedicine. Such […]


Continue.. CellCover Defines Temporal Progression in Conserved Cell Types and Informs oRG Evolution using scRNA-seq Data in Mammalian Neocortical Development

Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage

Kavli Affiliate: Jean Fan | Authors: Katy Boerner, Philip D Blood, Jonathan C Silverstein, Matthew Ruffalo, Sarah A Teichmann, Gloria Pryhuber, Ravi S Misra, Jeffrey M Purkerson, Jean Fan, John W Hickey, Gesmira Molla, Chuan Xu, Yun Zhang, Griffin M Weber, Yashvardhan Jain, Danial Qaurooni, Yongxin Kong, Andreas Bueckle and Bruce W Herr II | […]


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Spontaneous calcium transients in hair cell stereocilia

Kavli Affiliate: Dwight Bergles | Authors: Saman Hussain, Miloslav Sedlacek, Runjia Cui, Wendy Zhang-Hooks, Dwight E Bergles, Jung-Bum Shin, Katie Kindt and Bechara Kachar | Summary: The hair bundle of auditory and vestibular hair cells converts mechanical stimuli into electrical signals through mechanoelectrical transduction (MET). The MET apparatus is built around a tip link that […]


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Integrating gene expression and imaging data across Visium capture areas with visiumStitched

Kavli Affiliate: Keri Martinowich | Authors: Nicholas J. Eagles, Svitlana V. Bach, Madhavi Tippani, Prashanti Ravichandran, Yufeng Du, Ryan A. Miller, Thomas Hyde, Stephanie C. Page, Keri Martinowich and Leonardo Collado-Torres | Summary: Background Visium is a widely-used spatially-resolved transcriptomics assay available from 10x Genomics. Standard Visium capture areas (6.5mm by 6.5mm) limit the survey […]


Continue.. Integrating gene expression and imaging data across Visium capture areas with visiumStitched

A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology

Kavli Affiliate: Jin Kang | Authors: Yingying Zhang, Alden K Leung, Jin Joo Kang, Yu Sun, Guanxi Wu, Le Li, Jiayang Sun, Lily Cheng, Tian Qiu, Junke Zhang, Shayne Wierbowski, Shagun Gupta, James Booth and Haiyuan Yu | Summary: A major goal of cancer biology is to understand the mechanisms underlying tumorigenesis driven by somatically […]


Continue.. A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology

Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes risk

Kavli Affiliate: Michael Miller | Authors: Hannah Mummey, Weston Elison, Katha Korgaonkar, Ruth Elgamel, Parul Kudtarkar, Emily Griffin, Paola Benaglio, Michael Miller, Alokkumar Jha, Jocelyn E Manning Fox, Mark Mccarthy, Sebastian Preissl, Anna L Gloyn, Patrick E Macdonald and Kyle J Gaulton | Summary: Physiological variability in pancreatic cell type gene regulation and the impact […]


Continue.. Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes risk

3D histology reveals that immune response to pancreatic precancers is heterogeneous and depends on global pancreas structure

Kavli Affiliate: Denis Wirtz | Authors: Ashley L Kiemen, Cristina Almagro Perez, Valentina Matos Romero, AndrĂ© Forjaz, Alicia M Braxton, Lucie Dequiedt, Jeeun Parksong, Courtney D Cannon, Xuan Yuan, Sarah M Shin, Jaanvi Mahesh Babu, Elizabeth D Thompson, Toby C Cornish, Won Jin Ho, Laura D Wood, PeiHsun Wu, Arrate Munoz-Barrutia, Ralph H Hruban and […]


Continue.. 3D histology reveals that immune response to pancreatic precancers is heterogeneous and depends on global pancreas structure