Kavli Affiliate: Vikram Chib | Authors: Aram Kim and Vikram S. Chib | Summary: Expectations as a reference point shape our decisions to motivate effortful activity. Despite the important role of reference points in human performance, little is known about how the brain processes expectations to guide motivated exertion. Participants completed a reward-based effort task […]
Kavli Affiliate: Kristina Nielsen | Authors: Dallas C Khamiss, Augusto A Lempel, Brandon R Nanfito and Kristina Juliane Nielsen | Summary: A fundamental aspect of visual motion processing is the computation of motion direction. In ferrets, as in primates, selectivity for motion direction is found both in early cortical stages like the primary visual cortex […]
Kavli Affiliate: Jean Fan | Authors: Caleb Hallinan, Calixto-Hope G Lucas, Jr. and Jean Fan | Summary: Abstract Spatial transcriptomics technologies enable high-throughput quantification of gene expression at specific locations across tissue sections, facilitating insights into the spatial organization of biological processes. However, high costs associated with these technologies have motivated the development of deep […]
Kavli Affiliate: Denis Wirtz | Authors: John Michel, Andre Forjaz, Vasco Queiroga, Kelly Casella, Kaitlin Stivers, Helen Nguyen, Maria Browne, Feiyu Chen, Ada Tam, Omkar Dhaygude, Hongni Fan, Hitoaki Maehira, Cheng Ting Lin, Elise Gray-Gaillard, Talia Benducci, Suguru Yamauchi, Ife Shoyombo, Ziying Xu, Eugene Shenderov, Peng Huang, Denis Wirtz, Jennifer Elisseeff, Yun Chen, Malcolm V […]
Kavli Affiliate: Martin Lindquist | Authors: Bogdan Petre, Martin A Lindquist and Tor Wager | Summary: Brain maps (e.g. retinotopy, somatotopy) vary across individuals. This is thought to reflect underlying computational differences. However, artificial neural networks (ANNs) show that similar performance and internal representations can coexist with diverse circuit layouts. Consequently, we tested the presumption […]
Kavli Affiliate: Xiaoqin Wang | Authors: Chenggang Chen, Zhiyu Yang and Xiaoqin Wang | Summary: Whether the auditory cortex has parallel pathways for sound identification (“what”) and localization (“where”), and whether it contains a map of auditory space, is debated. Here, we examined the low-dimensional structure (manifold) of “what” and “where” representations in deep neural […]
Kavli Affiliate: Xiaoqin Wan | Authors: Chenggang Chen, Evan D Remington and Xiaoqin Wang | Summary: Cell types are the basic units of the cerebral cortex. Broad and narrow spike waveforms (BW and NW) are the primary criteria for classifying putative excitatory and inhibitory cortical neurons, particularly in non-human primates where genetic accessibility is limited. […]
Kavli Affiliate: Martin Lindquist | Authors: Zheng Ren, Patrick Sadil and Martin Lindquist | Summary: Aggregating neuroimaging data across sites and studies is increasingly common, yet site- and scanner-related batch effects can obscure meaningful biological variation and introduce spurious associations. Although ComBat and its extensions are widely used, they are primarily designed for single-metric (univariate) […]
Kavli Affiliate: Dwight Bergles | Authors: Jing-Xuan Lim, Ziqiang Wei, Sujatha Narayan, Yan Zhang, Jeremy P. Hasseman, Ilya Kolb, Jihong Zheng, Alireza Sheikhattar, Xuelong Mi, Wei Zheng, Xueying Yang, Mariam Beriashvili, Greg Fleishman, Caroline Wee, Chris de Zeeuw, Guoqiang Yu, Behtash Babadi, Mikail Rubinov, Loren L. Looger, Dwight E. Bergles, James E. Fitzgerald and Misha […]
Kavli Affiliate: Keri Martinowich | Authors: Aaron J Salisbury, Lourdes Figueroa, Keri Martinowich and Michael Totty | Summary: The risk of developing psychiatric disorders, particularly stress-related disorders such as major depressive disorder (MDD) and post-traumatic stress disorder (PTSD), is increased threefold in patients with epilepsy. While this increased risk may arise as a consequence of […]