Kavli Affiliate: Jin Kang | Authors: Kang Jin, Zuobai Zhang, Ke Zhang, Francesca Viggiani, Claire Callahan, Jian Tang, Bruce J. Aronow and Jian Shu | Summary: Single-cell spatial transcriptomics such as in-situ hybridization or sequencing technologies can provide subcellular resolution that enables the identification of individual cell identities, locations, and a deep understanding of subcellular […]

Kavli Affiliate: Richard Huganir | Authors: Sureni H. Sumathipala, Suha Khan, Robert A. Kozol, Yoichi Araki, Sheyum Syed, Richard L. Huganir and Julia Dallman | Summary: Background and Aims SYNGAP1 disorder is a prevalent genetic form of Autism Spectrum Disorder and Intellectual Disability (ASD/ID) and is caused by de novo or inherited mutations in one […]

Kavli Affiliate: Jeremiah Cohen | Authors: Emerson F Harkin, Cooper D Grossman, Jeremiah Y Cohen, Jean-Claude Béïque and Richard Naud | Summary: The in vivo responses of dorsal raphe nucleus (DRN) serotonin neurons to emotionally-salient stimuli are a puzzle. Existing theories centred on reward, surprise, or uncertainty individually account for some aspects of serotonergic activity […]

Kavli Affiliate: Vikram Chib | Authors: Salma Khatib, Vikram S. Chib and Firas Mawase | Summary: Motivational state plays a critical role in our ability to learn new motor skills; however, the mechanisms by which motivation influences motor learning are poorly understood. Using a motor learning paradigm in which motivation was varied in a trial-by-trial […]

Kavli Affiliate: Xiaoqin Wang | Authors: Lianglong Sun, Tengda Zhao, Xinyuan Liang, Mingrui Xia, Qiongling Li, Xuhong Liao, Gaolang Gong, Qian Wang, Chenxuan Pang, Qian Yu, Yanchao Bi, Pindong Chen, Rui Chen, Yuan Chen, Taolin Chen, Jingliang Cheng, Yuqi Cheng, Zaixu Cui, Zhengjia Dai, Yao Deng, Yuyin Ding, Qi Dong, Dingna Duan, Jia-Hong Gao, Qiyong […]

Kavli Affiliate: Michael Miller | Authors: Jamil Mahmud, Brittany W Geiler, Juthi Biswas, Michael J Miller, Julia E Myers, Stephen M Matthews, Amanda B Wass, Christine M O’Connor and Gary C Chan | Summary: Establishing a non-productive quiescent/silent infection within monocytes is essential for spread of human cytomegalovirus (HCMV). Yet, how HCMV establishes a quiescent […]

Kavli Affiliate: Keri Martinowich | Authors: Lukas M Weber, Heena R Divecha, Matthew N Tran, Sang Ho Kwon, Abby Spangler, Kelsey D Montgomery, Madhavi Tippani, Rahul Bharadwaj, Joel E Kleinman, Stephanie C Page, Thomas M Hyde, Leonardo Collado-Torres, Kristen R Maynard, Keri Martinowich and Stephanie C Hicks | Summary: Norepinephrine (NE) neurons in the locus […]

Kavli Affiliate: Michael Miller | Authors: Michael E Miller, Susan Sidell and Elizabeth A Ostrowski | Summary: Cooperative groups are susceptible to invasion by cheaters that reap the benefits but fail to pay the costs. Both theory and experimental work have shown that cheating can select for counter-adaptations to resist cheating. But then why is […]

Kavli Affiliate: Reza Shadmehr | Authors: Erik M. Summerside, Robert J Courter, Reza Shadmehr and Alaa A. Ahmed | Summary: As people age, they move slower. Is age-related reduction in vigor a reflection of a reduced valuation of reward by the brain, or a consequence of increased effort costs by the muscles? Here, we quantified […]

Kavli Affiliate: Cynthia F. Moss | Authors: Michael A Pardo, Kurt Fristrup, David S Lolchuragi, Joyce Poole, Petter Granli, Cynthia Moss, Iain Douglas-Hamilton and George Wittemyer | Summary: Personal names are a universal feature of human language, yet few analogs exist in other species. While dolphins and parrots address conspecifics by imitating the calls of […]