Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Alex Kolodkin | Authors: Tzu-Huai Lin, Annika Balraj, Timour Al-Khindi, James K Kiraly, Felice A Dunn and Alex L Kolodkin | Summary: In vertebrates, gaze stabilization during global visual motion requires ON direction-selective ganglion cells (oDSGCs) in the Accessory Optic […]

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Kathleen Cullen and James Knierim | Authors: Alexandra Cheng, Tate DeWeese, Yueqing Zhou, Yotaro Sueoka, Sai Koukuntla, Merrill Green, Kathleen Cullen, James Knierim, Austin Graves and Timothy Harris | Summary: High-density Neuropixels probes enable the study of large neural populations […]

Kavli Affiliate: Richard Huganir | Authors: Chih-Ming Chen, Yu-Min Huang, Chih-Ching Chung, Richard C. Johnson, Cheng-Ya Tsai, Yu-Han Chen, Han L. Tan, Fu-Yun Hsiao, Richard L. Huganir and Shu-Ling Chiu | Summary: AMPA receptors (AMPARs) mediate fast excitatory synaptic transmission and are essential for neuronal development and brain function. We investigated the role of a […]

Kavli Affiliate: Jean Fan | Authors: Dee Velazquez, Caleb Hallinan, Roujin An, Kalen Clifton and Jean Fan | Summary: Motivation Imaging-based spatially resolved transcriptomics (imSRT) technologies provide high-throughput molecular-resolution spatial characterization of genes within cells. Conventional analysis methods to identify cell-types and states in imSRT data rely on gene count matrices derived from tallying the […]

Kavli Affiliate: Michael Beer | Authors: Jos J. A. G. Kamps, Philip Hinchliffe, Johan Glerup, Emily I. Freeman, Pauline A. Lang, Catherine L Tooke, Michael Beer, Laura Parkinson, Do-Heon Gu, Sehan Park, Nicholas Devenish, Tiankun Zhou, Anastasya Shilova, Patrick Rabe, Christopher J Schofield, Jim Spencer, Jaehyun Park, Robin Owen, Allen M. Orville and Pierre Aller […]

Kavli Affiliate: Michael Beer | Authors: Philip Hinchliffe, Catherine L Tooke, Michael Beer, Pierre Aller, Jos JAG Kamps, Laura Parkinson, Tiankun Zhou, Nicholas Devenish, Do-Heon Gu, Anastasya Shilova, Matthew J Rodrigues, Abbey Telfer, Agata Butryn, Marko Hanževački, Emily I Freeman, Sehan Park, Christopher J Schofield, Jaehyun Park, Robin L Owen, Adrian J Mulholland, Allen M […]

Kavli Affiliate: Shreesh P. Mysore | Authors: Arunima Banerjee, Ninad B. Kothari and Shreesh P. Mysore | Summary: Competitive stimulus interactions across the space map in the midbrain superior colliculus (SC) are essential for spatial decision-making. Here, with electrophysiological recordings in intermediate and deep layers of the mouse SC (SCid), we discovered that rules and […]

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Patricia Janak | Authors: Robin Magnard, Daianna Gonzalez-Padilla, Ege A. Yalcinbas, Emma Chaloux-Pinette, Nicholas J. Eagles, Michael S. Totty, Patricia H. Janak, Leonardo Collado-Torres and Kristen R. Maynard | Summary: Fentanyl is a potent synthetic opioid associated with overdose. However, […]

Kavli Affiliate: Keri Martinowich | Authors: Jason J Rehg, Daniel E Olivares, Ye Li, Keri Martinowich, Greg V Carr and Jorge Miranda-Barrientos | Summary: control to allocate cognitive resources toward behaviorally relevant stimuli based on learned context and expectations. mPFC neurons project to multiple cortical and subcortical regions, including the locus coeruleus (LC)—the brain’s primary […]

Kavli Affiliate: Martin Lindquist | Authors: Jungin Choi, Abhirup Datta and Martin Lindquist | Summary: Task-based fMRI is commonly analyzed using voxel-wise general linear models, a non-spatial scalable approach that can yield fragmented activation maps. Spatial alternatives such as kernel smoothing and Bayesian models address this but either blur activation boundaries or are computationally prohibitive […]