Kavli Affiliate: Reza Shadmehr | Authors: Paul Hage, In Kyu Jang, Vivian Looi, Mohammad Amin Fakharian, Simon P Orozco, Ehsan Sedaghat-Nejad, Jay Pi and Reza Shadmehr | Summary: We prefer to decline effortful rewards, but if the circumstances require it, we will move only slowly to harvest them. Why should economic variables such as reward […]
Kavli Affiliate: Patricia Janak | Authors: Eric Garr, Yifeng Cheng, Huijeong Jeong, Sara Brooke, Laia Castell, Aneesh Bal, Robin Magnard, Vijay Mohan K. Namboodiri and Patricia H. Janak | Summary: Learning causal relationships relies on understanding how often one event precedes another. To gain an understanding of how dopamine neuron activity and neurotransmitter release change […]
Kavli Affiliate: Michael Higley, Alipasha Vaziri, Kristina Nielsen | Authors: Che-Hang Yu, Yiyi Yu, Liam M. Adsit, Jeremy T. Chang, Jad Barchini, Andrew H. Moberly, Hadas Benisty, Jinkyung Kim, Brent K Young, Kathleen Heng, Deano M. Farinella, Austin Leikvoll, Rishaab Pavan, Rachel Vistein, Brandon R. Nanfito, David G. C. Hildebrand, Santiago Otero-Coronel, Alipasha Vaziri, Jeffery […]
Kavli Affiliate: Seth Blackshaw | Authors: Cheng Qian, Ying Xin, Cheng Qi, Hui Wang, Bryan C. Dong, Donald Zack, Seth Blackshaw, Samer Hattar, Feng-Quan Zhou and Jiang Qian | Summary: The progressive death of mature neurons often results in neurodegenerative diseases. While the previous studies have mostly focused on identifying intrinsic mechanisms controlling neuronal survival, […]
Kavli Affiliate: Michael Miller | Authors: Taylor Bertucci, Kathryn R Bowles, Steven Lotz, Le Qi, Katherine Stevens, Susan K Goderie, Susan Borden, Laura Oja, Keith Lane, Ryan Lotz, Hailey Lotz, Rebecca Chowdhury, Shona Joy, Brigitte L Arduini, David C Butler, Michael Miller, Heide Baron, Carl Alexander Sandhof, M. Catarina Silva, Stephen J Haggarty, Celeste M […]
Kavli Affiliate: Kishore V. Kuchibhotla, Adam S. Charles | Authors: Sharlen Moore, Zyan Wang, Ziyi Zhu, Ruolan Sun, Angel Lee, Adam Charles and Kishore V Kuchibhotla | Summary: A fundamental tenet of animal behavior is that decision-making involves multiple ‘controllers.’ Initially, behavior is goal-directed, driven by desired outcomes, shifting later to habitual control, where cues […]
Kavli Affiliate: Keri Martinowich | Authors: Lionel A Rodriguez, Matt N Tran, Renee Garcia-Flores, Elizabeth A Pattie, Sun-Hong Kim, Joo Heon Shin, Yong Kyu Lee, Heena R Divecha, Carly Montoya, Andrew E Jaffe, Leonardo Collado Torres, Stephanie Cerceo Page and Keri Martinowich | Summary: The lateral septum (LS), a GABAergic structure located in the basal […]
Kavli Affiliate: Patricia Janak | Authors: Kurt M. Fraser, Tabitha H. Kim, Matilde Castro, Céline Drieu, Yasmin Padovan-Hernandez, Bridget Chen, Fiona Pat, David J. Ottenheimer and Patricia H. Janak | Summary: The ability to evaluate and select a preferred option among a variety of available offers is an essential aspect of goal-directed behavior. Dysregulation of […]
Kavli Affiliate: David Linden | Authors: Daniel C de la Fuente, Claudia Tamburini, Emily Stonelake, William J Griffiths, Jeremy Hall, Michael J Owen, David E. J. Linden, Andrew Pocklington, Yuqin Wang and Meng Li | Summary: Dysregulation in neural progenitor proliferation and neuronal differentiation has been increasingly recognised as a common pathology in neural cells […]
Kavli Affiliate: Alex Kolodkin | Authors: Joelle M Dorskind, Sriram Sudarsanam, Randal A Hand, Jakub Ziak, Maame Amoah-Dankwah, Luis Guzman-Clavel, John Lee Soto-Vargas and Alex L Kolodkin | Summary: Proper cortical lamination is essential for cognition, learning, and memory. Within the somatosensory cortex, pyramidal excitatory neurons elaborate axon collateral branches in a laminar-specific manner that […]