Kavli Affiliate: Michael Beer | Authors: Hira Jabeen, Michael Beer, James Spencer, Marc W van der Kamp, H Adrian Bunzel and Adrian J Mulholland | Summary: MAntimicrobial resistance is a public health crisis. Limited understanding of the catalytic drivers in resistance-mediating enzymes such as β-lactamases hinders our ability to combat this crisis. Here, we dissect […]
Kavli Affiliate: Denis Wirtz | Authors: Jeanette A.I. Johnson, Genevieve L Stein-O’Brien, Max Booth, Randy Heiland, Furkan Kurtoglu, Daniel Bergman, Elmar Bucher, Atul Deshpande, Andre Forjaz, Michael Getz, Ines Godet, Melissa Lyman, John Metzcar, Jacob Mitchell, Andrew Raddatz, Heber L. Rocha, Jacobo Solorzano, Aneequa Sundus, Yafei Wang, Daniele M. Gilkes, Luciane T. Kagohara, Ashley L. […]
Kavli Affiliate: Seth Blackshaw | Authors: Nguyet Le, Trieu-Duc Vu, Isabella Palazzo, Ritvik Pulya, Yehna Kim, Seth Blackshaw and Thanh Hoang | Summary: Neurogenic competence is actively repressed in mature mammalian Muller glial cells, and previous studies have predicted that this is in part mediated by active Notch signaling. To determine whether global loss of […]
Kavli Affiliate: Jeremias Sulam | Authors: Helge J Zollner, Christopher B. Davies-Jenkins, Dunja B. Simicic, Assaf Tal, Jeremias Sulam and Georg Oeltzschner | Summary: Purpose: The interest in application and modeling of dynamic MRS has recently grown. Therefore, it is imperative to systematically investigate accuracy, precision, and uncertainty estimation of 2D modeling algorithms. 2D modeling […]
Kavli Affiliate: Martin Lindquist | Authors: Brent William Stewart, Michael L Keaser, Hwiyoung Lee, Sarah M Margerison, Matthew A Cormie, Massieh Moayedi, Martin Lindquist, Shuo Chen, Brian N. Mathur and David A Seminowicz | Summary: Aberrant cognitive network activity and cognitive deficits are established features of chronic pain. However, the nature of cognitive network alterations […]
Kavli Affiliate: Jin Kang | Authors: Brian J Bender, Julie E Pickett, Joao Braz, Hye Jin Kang, Stefan Gahbauer, Karnika Bhardwaj, Sian Rodriguez-Rosado, Yongfeng Liu, Manish Jain, Allan Basbaum, Bryan L Roth and Brian K. Shoichet | Summary: While opioid drugs remain among the most effective analgesics for pain management, adverse effects limit their use. […]
Kavli Affiliate: Alex Kolodkin | Authors: Noelle Thielman, Vanessa Funes, Sanjana Davuluri, Hector lbanez, Wei-Chih Sun, Juan Fu, Keyu Li, Stephen Muth, Xingyi Pan, Kenji Fujiwara, Dwayne Thomas, MacKenzie Henderson, Selina Shiqing Teh, Qingfeng Zhu, Elizabeth Thompson, Elizabeth M Jaffee, Alex Kolodkin, Fengxi Meng and Lei Zheng | Summary: Axon guidance molecules were found to […]
Kavli Affiliate: Michael Miller | Authors: David A. Alvarado, Luis Alberto Ibarra-Sanchez, Annemarie R. Mysonhimer, Tauseef A Khan, Rong Cao, Michael J. Miller and Hannah Holscher | Summary: Background Bifidobacterium animalis ssp. lactis DN-173 010/CNCM I-2494 (B. animalis) is a probiotic strain commonly added to yogurt. Yogurt and honey are a popular culinary pairing. Honey […]
Kavli Affiliate: Laurent Younes & Donald Geman | Authors: Kun Yang, Koko Ishizuka, Andrew P Lane, Zui Narita, Arisa Hayashida, Yukiko Y Lema, Emma Heffron, Haydn Loudd, Maeve Schumacher, Shin-ichi Kano, Toshifumi Tomoda, Atsushi Kamiya, Minghong Ma, Donald Geman, Laurent Younes and Akira Sawa | Summary: Biopsy is crucial in clinical medicine to obtain tissues […]
Kavli Affiliate: Jean Fan | Authors: Rafael dos Santos Peixoto, Brendan F Miller, Maigan A Brusko, Lyla Atta, Manjari Anant, Mark A Atkinson, Todd M Brusko, Clive H Wasserfall and Jean Fan | Summary: Spatially resolved omics technologies provide molecular profiling of cells while preserving their organization within tissues, allowing for the evaluation of cell-type […]