Blocking apoptosis promotes survival and alters developmental dynamics of human retinal ganglion cells in retinal organoids

Kavli Affiliate: Seth Blackshaw | Authors: Jingliang Simon Zhang, Brian Guy, Clayton P Santiago, Caterina Tiozzo, Meghana Sreenath, Ya-Wen Chen, Seth Blackshaw and Robert J Johnston, Jr | Summary: Retinal ganglion cells (RGCs) are the projection neurons that transmit visual information from the retina to the brain. In many species, a substantial proportion of RGCs […]


Continue.. Blocking apoptosis promotes survival and alters developmental dynamics of human retinal ganglion cells in retinal organoids

Novel Predictive Spatial Biomarker in Non-Small Cell Lung Carcinoma: The Diversity of Niches Unlocking Treatment Sensitivity (DONUTS)

Kavli Affiliate: Alexander Szalay | Authors: Tricia R Cottrell, Jeffrey S Roskes, Michael Fotheringham, Emily Cohen, Boyang Zhang, Logan L Engle, Daphne Wang, Elizabeth Will, Joel C Sunshine, Daniel Jimenez-Sanchez, Zhen Zheng, Justina X Caushi, Jiajia Zhang, Nina D’Amiano, Julie Stein-Deutsch, Sonali Uttam, Katie Pirie, Darah Vlaminck, Michelle Mataj, Alexa Fiorante, Nicole Espinosa, Teodora Popa, […]


Continue.. Novel Predictive Spatial Biomarker in Non-Small Cell Lung Carcinoma: The Diversity of Niches Unlocking Treatment Sensitivity (DONUTS)

Spatiomolecular mapping reveals anatomical organization of heterogeneous cell types in the human nucleus accumbens

Kavli Affiliate: Keri Martinowich | Authors: Prashanthi Ravichandran, Svitlana V. Bach, Robert A. Phillips III, Madeline R. Valentine, Nicholas J. Eagles, Yufeng Du, Ishbel Del Rosario, Ryan A. Miller, Heena R. Divecha, Madhavi Tippani, Kelsey D. Montgomery, Joel E. Kleinman, Shizhong Han, Stephanie Cerceo Page III, Thomas M. Hyde, Leonardo Collado Torres, Alexis Battle, Keri […]


Continue.. Spatiomolecular mapping reveals anatomical organization of heterogeneous cell types in the human nucleus accumbens

Exploring endothelial cell environments across organs in spatially resolved omics data

Kavli Affiliate: Jean Fan | Authors: Yashvardhan Jain, Jodie Jepson, Roy Chen, Elizabeth Maier, Bruce W. Herr II, Aleix Puig-Barbe, Ellen M. Quardokus, Danial Qaurooni, Clarence Yapp, Samuel L. Ewing, Archibald Enninful, Negin Farzad, Andreas Bueckle, Quinn T. Easter, Bruno Matuck, Chenchen Zhu, Emma Marie Monte, Jeffrey M. Purkerson, Matthew Jehrio, Ravi S. Misra, Rong […]


Continue.. Exploring endothelial cell environments across organs in spatially resolved omics data

Toward navigating emotional states using real-time representational similarity analysis fMRI neurofeedback – a feasibility study

Kavli Affiliate: David Linden | Authors: Xuelei Wang, Assunta Ciarlo, Michael Luehrs, Alexander Atanasyan, David Böken, Jürgen Roßmann, Michael Schluse, Maren Jäger, Marisa Nordt, Fengyu Cong, Klaus Mathiak, David Linden, Rainer Goebel, David MA Mehler and Jana Zweerings | Summary: Real-time functional magnetic resonance imaging neurofeedback (rt-fMRI-NF) is a promising non-invasive brain-computer-interface (BCI) technique for […]


Continue.. Toward navigating emotional states using real-time representational similarity analysis fMRI neurofeedback – a feasibility study

JACUZI-SD: An automated, high-throughput, minimally stressful approach to sleep depriving larval zebrafish.

Kavli Affiliate: Seth Blackshaw | Authors: Leah J Elias, Harrison Khoo, Francois Kroll, Caroline Zhang, Soojung C Hur, Jason Rihel and Seth Blackshaw | Summary: While sleep deprivation broadly disrupts health and well-being, the neural and molecular mechanisms that signal increased sleep pressure remain poorly understood. A key obstacle to progress is the fact that […]


Continue.. JACUZI-SD: An automated, high-throughput, minimally stressful approach to sleep depriving larval zebrafish.

3D multi-omic mapping of whole nondiseased human fallopian tubes at cellular resolution reveals a large incidence of ovarian cancer precursors

Kavli Affiliate: Denis Wirtz | Authors: André Forjaz, Vasco Queiroga, Yajuan Li, Alfredo Hernandez, Ashleigh Crawford, Xiaoyu Qin, Mei Zhong, Margarita Tsapatsis, Saurabh Joshi, Donald Kramer, Oliver Nizet, Habin Bea, Yuhan Li, Shuo Qin, Robert O Flynn, Mingder Yang, Britanny Pratt, Fan Wu, Paul Gensbigler, Max Blecher, Pei-Hsun Wu, Luciane Tsukamoto Kagohara, Ie Ming Shih, […]


Continue.. 3D multi-omic mapping of whole nondiseased human fallopian tubes at cellular resolution reveals a large incidence of ovarian cancer precursors

CNS-Tau Specific Antibodies Illuminate Disease Signatures Across Tauopathies

Kavli Affiliate: Michael Miller | Authors: Lei Liu, Yin Zheng, Luke Slominski, Qimin Quan, Adriana Saba, Jean-Pierre Bellier, Han-Bin Yoo, Andrea Roman, Elizabeth L Hennessey, Samadhi Wijethunga, Elif Lara Okyay, Michael B Miller, Hyun-Sik Yang, Dennis J Selkoe and Jasmeer Chhatwal | Summary: Background Alternative splicing of the MAPT gene produces distinct tau isoforms in […]


Continue.. CNS-Tau Specific Antibodies Illuminate Disease Signatures Across Tauopathies

Altered NPTX2 dynamics associated with impaired cognitive aging

Kavli Affiliate: Michela Gallagher | Authors: Rebecca P. Haberman, Ana Delgado, Meifang Xiao, Ming Teng Koh, Ashley A Becker, Shiyu Ji, Paul F Worley, Michela Gallagher and Audrey E. Branch | Summary: Changes in synaptic integrity and neural activity homeostasis are hallmarks of brain aging and are closely tied to cognitive outcomes. Yet, defining their […]


Continue.. Altered NPTX2 dynamics associated with impaired cognitive aging

Separating the control of moving and holding still in post-stroke arm paresis

Kavli Affiliate: Reza Shadmehr | Authors: Alkis M. Hadjiosif, Kahori Kita, Scott T. Albert, Robert A. Scheidt, Reza Shadmehr and John W. Krakauer | Summary: Moving and holding still have been posited to be under separate control regimes for both eye and arm movements. The paretic arm after stroke is notable for abnormalities both at […]


Continue.. Separating the control of moving and holding still in post-stroke arm paresis