Rapid rebalancing of co-tuned ensemble activity in the auditory cortex

Kavli Affiliate: Patrick Kanold | Authors: HiJee Kang, Travis Babola and Patrick O Kanold | Summary: Sensory information is represented by small neuronal ensembles in sensory cortices. Neuronal activity shows high trial-by-trial variability in that repeated presentation of the same stimulus, e. g., multiple presentations of the same sound activate differing ensembles in the auditory […]


Continue.. Rapid rebalancing of co-tuned ensemble activity in the auditory cortex

The value of initiating a pursuit in temporal decision-making

Kavli Affiliate: Marshall Hussain Shuler | Authors: Elissa Sutlief, Charlie Walters, Tanya Marton and Marshall G Hussain Shuler | Summary: Reward rate maximization is a prominent normative principle commonly held in behavioral ecology, neuroscience, economics, and artificial intelligence. Here, we identify and compare equations for evaluating the worth of initiating pursuits that an agent could […]


Continue.. The value of initiating a pursuit in temporal decision-making

Network nature of ligand-receptor interactions underlies disease comorbidity in the brain

Kavli Affiliate: Keri Martinowich | Authors: Melissa Grant-Peters, Aine Fairbrother-Browne, Amy Hicks, Boyi Guo, Regina H. Reynolds, Louise A. Huuki-Myers, Nick Eagles, Jonathan Brenton, Sonia Garcia-Ruiz, Nicholas Wood, Sonia Gandhi, Keri Martinowich, Kristen Maynard, Leonardo Collado-Torres and Mina Ryten | Summary: Neurodegenerative disorders have overlapping symptoms and have high comorbidity rates, but this is not […]


Continue.. Network nature of ligand-receptor interactions underlies disease comorbidity in the brain

Functional connectome through the human life span

Kavli Affiliate: Xiaoqin Wang | Authors: Lianglong Sun, Tengda Zhao, Xinyuan Liang, Mingrui Xia, Qiongling Li, Xuhong Liao, Gaolang Gong, Qian Wang, Chenxuan Pang, Qian Yu, Yanchao Bi, Pindong Chen, Rui Chen, Yuan Chen, Taolin Chen, Jingliang Cheng, Yuqi Cheng, Zaixu Cui, Zhengjia Dai, Yao Deng, Yuyin Ding, Qi Dong, Dingna Duan, Jia-Hong Gao, Qiyong […]


Continue.. Functional connectome through the human life span

Spatial Single-cell Analysis Decodes Cortical Layer and Area Specification

Kavli Affiliate: Michael Miller | Authors: Xuyu Qian, Kyle Coleman, Shunzhou Jiang, Andrea J Kriz, Jack H Marciano, Chunyu Luo, Chunhui Cai, Monica D Manam, Emre Caglayan, Aoi Otani, Urmi Ghosh, Diane D Shao, Rebecca E Andersen, Jennifer E Neil, Robert Johnson, Alexandra LeFevre, Jonathan L Hecht, Michael B Miller, Liang Sun, Carsen Stringer, Mingyao […]


Continue.. Spatial Single-cell Analysis Decodes Cortical Layer and Area Specification

Temporal-Coherence Induces Binding in Responses to Sound Sequences in Ferret Auditory Cortex

Kavli Affiliate: Mounya Elhilali/p> | Authors: Kai Lu, Kelsey Dutta, Ali Mohammed, Mounya Elhilali and Shihab Shamma | Summary: Binding the attributes of a sensory source is necessary to perceive it as a unified entity, one that can be attended to and extracted from its surrounding scene. In auditory perception, this is the essence of […]


Continue.. Temporal-Coherence Induces Binding in Responses to Sound Sequences in Ferret Auditory Cortex

Transcriptional Control of Neocortical Size and Microcephaly

Kavli Affiliate: Kristina Nielsen Loyal Goff | Authors: Soraia Barao, Yijun Xu, Rachel Vistein, Loyal Goff, Kristina Nielsen, Byoung-Il Bae, Richard S. Smith, Christopher A Walsh, Genevieve Stein O Brien and Ulrich Muller | Summary: The mammalian neocortex differs vastly in size and complexity between mammalian species, yet the mechanisms that lead to an increase […]


Continue.. Transcriptional Control of Neocortical Size and Microcephaly

Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts

Kavli Affiliate: Jean Fan | Authors: Jude Marvin Phillip, Pratik Kamat, Nico Macaluso, Chanhong Min, Yukang Li, Anshika Agrawal, Aaron Winston, Lauren Pan, Bartholomew Marvin Starich, Teasia Stewert, Pei-Hsun Wu, Jean Fan and Jeremy Walston | Summary: Cellular senescence is an established driver of aging, exhibiting context-dependent phenotypes across multiple biological length-scales. Despite its mechanistic […]


Continue.. Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts

Spatiotemporal analysis of gene expression in the human dentate gyrus reveals age-associated changes in cellular maturation and neuroinflammation

Kavli Affiliate: Keri Martinowich | Authors: Anthony Dial Ramnauth, Madhavi Tippani, Heena R. Divecha, Alexis R. Papariello, Ryan A Miller, Erik D Nelson, Elizabeth A. Pattie, Joel E. Kleinman, Kristen R. Maynard, Leonardo Collado-Torres, Thomas M. Hyde, Keri Martinowich, Stephanie C Hicks and Stephanie Cerceo Page | Summary: The dentate gyrus of the hippocampus is […]


Continue.. Spatiotemporal analysis of gene expression in the human dentate gyrus reveals age-associated changes in cellular maturation and neuroinflammation