Kavli Affiliate: Rafael Yuste | Authors: Nicola Masala, Manuel Mittag, Eleonora Ambrad Giovannetti, Darik A O’Neil, Fabian J Distler, Peter Rupprecht, Fritjof Helmchen, Rafael Yuste, Martin Fuhrmann, Heinz Beck, Michael Wenzel and Tony Kelly | Summary: Genetically encoded calcium indicators (GECIs) such as GCaMP are an invaluable tool in neuroscience to monitor neuronal activity using […]

Kavli Affiliate: Stefano Fusi & Mazen Kheirbek | Authors: Frances Xia, Valeria Fascianelli, Nina Vishwakarma, Frances Grace Ghinger, Stefano Fusi and Mazen Kheirbek | Summary: The neural dynamics that underlie divergent anhedonic responses to stress remain unclear. Here, we identified neuronal dynamics in an amygdala-hippocampal circuit that distinguish stress resilience and susceptibility. In a reward-choice […]

Kavli Affiliate: Rudy Behnia | Authors: Ishani Ganguly, Emily L. Heckman, Ashok Litwin-Kumar, E. Josephine Clowney and Rudy Behnia | Summary: The arthropod mushroom body is well-studied as an expansion layer that represents olfactory stimuli and links them to contingent events. However, 8% of mushroom body Kenyon cells in Drosophila melanogaster receive predominantly visual input, […]

Kavli Affiliate: Richard Axel | Authors: Jennifer J Bussell, Ryan P Badman, Christian David Márton, Ethan S Bromberg-Martin, LF Abbott, Kanaka Rajan and Richard Axel | Summary: HAnimals are motivated to acquire knowledge of their world. They seek information that does not influence reward outcomes suggesting that information has intrinsic value. We have asked whether […]

Kavli Affiliate: Costa, Rui | Authors: Joseph Pemberton, Paul Chadderton and Rui Ponte Costa | Summary: Abstract To drive behavior, the cortex must bridge sensory cues with future outcomes. However, the principles by which cortical networks learn such sensory-behavioural transformations remain largely elusive. Here, we posit that the cerebellum assumes a crucial role in driving […]

Kavli Affiliate: Michael Goldberg | Authors: Michael E. Goldberg, Olivia Rutler, Randy M. Bruno, Jung Man Park, Serena Persaud, Stylianos Kosmidis and Nina Hirano | Summary: Because the retina moves constantly, the retinotopic representation of the visual world is spatially inaccurate and the brain must transform this spatially inaccurate retinal signal to a spatially accurate […]

Kavli Affiliate: Franck Polleux, Attila Losonczy | Authors: Kevin C Gonzalez, Adrian Negrean, Zhenrui Liao, Franck Polleux and Attila Losonczy | Summary: Learning and memory are fundamental to adaptive behavior and cognition. Various forms of synaptic plasticity have been proposed as cellular substrates for the emergence of feature selectivity in neurons underlying episodic memory. However, […]

Kavli Affiliate: Liam Paninski | Authors: Marcus A. Triplett, Marta Gajowa, Benjamin Antin, Masato Sadahiro, Hillel Adesnik and Liam Paninski | Summary: Abstract Discovering how neural computations are implemented in the cortex at the level of monosynaptic connectivity requires probing for the existence of synapses from possibly thousands of presynaptic candidate neurons. Two-photon optogenetics has […]

Kavli Affiliate: Stefano Fusi | Authors: Sean Chih-Hsiung Lim, Stefano Fusi and Rene Hen | Summary: The ventral hippocampus is a critical node in the distributed brain network that controls anxiety. Using miniature microscopy and calcium imaging, we recorded ventral CA1 (vCA1) neurons in freely moving mice as they explored variants of classic behavioral assays […]