Organization and Plasticity of Inhibition in Hippocampal Recurrent Circuits

Kavli Affiliate: Attila Losonczy | Authors: Bert Vancura, Tristan Geiller and Attila Losonczy | Summary: Excitatory-inhibitory interactions structure recurrent network dynamics for efficient cortical computations. In the CA3 area of the hippocampus, recurrent circuit dynamics, including experience-induced plasticity at excitatory synapses, are thought to play a key role in episodic memory encoding and consolidation via […]


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Robust Online Multiband Drift Estimation in Electrophysiology Data

Kavli Affiliate: Liam Paninski | Authors: Charlie Windolf, Angelique C Paulk, Yoav Kfir, Eric Trautmann, Samuel Garcia, Domokos Meszéna, William Muñoz, Irene Caprara, Mohsen Jamali, Julien C Boussard, Ziv M Williams, Sydney S Cash, Liam Paninski and Erdem Varol | Summary: High-density electrophysiology probes have opened new possibilities for systems neuroscience in human and non-human […]


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Human synaptic neoteny requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition

Kavli Affiliate: Franck Polleux | Authors: Baptiste Libe-Philippot, Ryohei Iwata, Aleksandra J Recupero, Keimpe Wierda, Martyna Ditkowska, Vaiva Gaspariunaite, Ben Vermaercke, Eugenie Peze-Heidsieck, Daan Remans, Cecile Charrier, Franck Polleux and Pierre Vanderhaeghen | Summary: Human-specific (HS) genes are potential drivers of brain evolution, but their impact on human neuron development and disease remains unclear. Here […]


Continue.. Human synaptic neoteny requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition

A frontosensory circuit for visual context processing is synchronous in the theta/alpha band

Kavli Affiliate: Darcy Peterka | Authors: Georgia Bastos, Jacob T Holmes, Jordan M Ross, Anna M Rader, Connor G Gallimore, Darcy S Peterka and Jordan P Hamm | Summary: Visual processing is strongly influenced by context. Stimuli that deviate from contextual regularities elicit augmented responses in primary visual cortex (V1). These heightened responses, known as […]


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Phased nanopore assembly with Shasta and modular graph phasing with GFAse

Kavli Affiliate: Richard Axel | Authors: Ryan Lorig-Roach, Melissa Meredith, Jean Monlong, Miten Jain, Hugh Olsen, Brandy McNulty, David Porubsky, Tessa G. Montague, Julian Lucas, Chris Condon, Jordan Eizenga, Sissel Juul, Sean McKenzie, Sara Simmonds, Jimin Park, Mobin Asri, Sergey Koren, Evan Eichler, Richard Axel, Bruce Martin, Paolo Carnevali, Karen Miga and Benedict Paten | […]


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Spatial heterogeneity in biofilm metabolism elicited by local control of phenazine methylation

Kavli Affiliate: Wei Min | Authors: Christopher R. Evans, Marina K. Smiley, Sean Asahara Thio, Mian Wei, Alexa Price-Whelan, Wei Min and Lars E.P. Dietrich | Summary: Within biofilms, gradients of electron acceptors such as oxygen stimulate the formation of physiological subpopulations. This heterogeneity can enable cross-feeding and promote drug resilience, features of the multicellular […]


Continue.. Spatial heterogeneity in biofilm metabolism elicited by local control of phenazine methylation

Alteration of functional connectivity in the cortex and major brain networks of non-human primates following focused ultrasound exposure

Kavli Affiliate: Vincent Ferrera | Authors: Dong Liu, Fabian A Munoz Silva, Soroosh Sanatkhani, Antonios Pouliopoulos, Elisa Konofagou, Jack Grinband and Vincent P. Ferrera | Summary: Focused ultrasound (FUS) is a non-invasive neuromodulation technology that is being investigated for potential treatment of neurological and psychiatric disorders. Focused ultrasound combined with microbubbles can temporarily open the […]


Continue.. Alteration of functional connectivity in the cortex and major brain networks of non-human primates following focused ultrasound exposure

Tuned geometries of hippocampal representations meet the demands of social memory

Kavli Affiliate: Stefano Fusi | Authors: Lara M. Boyle, Lorenzo Posani, Sarah Irfan, Steven A. Siegelbaum and Stefano Fusi | Summary: Social recognition consists of multiple memory processes, including the detection of familiarity – the ability to rapidly distinguish familiar from novel individuals – and recollection – the effortful recall of where a social episode […]


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Neuronal birthdate reveals topography in a vestibular brainstem circuit for gaze stabilization

Kavli Affiliate: Elizabeth Hillman | Authors: Dena Goldblatt, Stephanie Huang, Marie R. Greaney, Kyla R. Hamling, Venkatakaushik Voleti, Citlali Perez-Campos, Kripa B. Patel, Wenze Li, Elizabeth M. C. Hillman, Martha W. Bagnall and David Schoppik | Summary: Abstract Across the nervous system, neurons with similar attributes are topographically organized. This topography reflects developmental pressures. Oddly, […]


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A quick and cost-effective method for DNA-free total RNA isolation using magnetic silica beads

Kavli Affiliate: Aniruddha Das | Authors: Aniruddha Das, Debojyoti Das, Arundhati Das and Amaresh Chandra Panda | Summary: Current RNA purification methods widely use silica-based columns that allow quick isolation of high-quality and good quantities of RNA. However, the major limitations include high cost, the requirement of different kits for small RNA isolation, genomic DNA […]


Continue.. A quick and cost-effective method for DNA-free total RNA isolation using magnetic silica beads