Learning shapes neural geometry in the prefrontal cortex

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Rui Costa | Authors: Michal J. Wojcik, Jake P. Stroud, Dante F. Wasmuht, Makoto Kusunoku, Mikiko Kadohisa, Mark J Buckley, Rui Ponte Costa, Nicholas E. Myers, Laurence T. Hunt, John Duncan and Mark G. Stokes | Summary: The relationship between […]


Continue.. Learning shapes neural geometry in the prefrontal cortex

Global context rapidly shapes sensory responses in V1

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Darcy Peterka | Authors: Darcy S Peterka, Fumiyasu Imai, Jordan M Ross, Georgia Bastos, Molly Hornick, Lital Rachmany, Connor G Gallimore, Adam Hockley and Jordan P Hamm | Summary: Context modulates sensory processing in the cerebral cortex by suppressing responses […]


Continue.. Global context rapidly shapes sensory responses in V1

When and why modular representations emerge

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Stefano Fusi | Authors: W. Jeffrey Johnston and Stefano Fusi | Summary: Experimental and theoretical work has argued both for and against the existence of specialized sub-populations of neurons (modules) within single brain regions. By studying artificial neural networks, we […]


Continue.. When and why modular representations emerge

Rarely categorical and highly separable: how neural representations change along the cortical hierarchy

Kavli Affiliate: Stefano Fusi and Liam Paninski | Authors: Lorenzo Posani, Shuqi Wang, Samuel Muscinelli, Liam Paninski and Stefano Fusi | Summary: A long-standing debate in neuroscience concerns whether individual neurons are organized into functionally distinct populations that encode information differently (“categorical” representations [1–3]) and the implications for neural computation. Here, we systematically analyzed how […]


Continue.. Rarely categorical and highly separable: how neural representations change along the cortical hierarchy

A neuron type-specific microexon in Ank3/ankyrin-G modulates calcium activity and neuronal excitability

Kavli Affiliate: Stavros Lomvardas | Authors: Shah Alam, Georgia Dermentzaki, David Cabrera Garcia, Miao Li, Ruizhi Wang, Melissa Campbell, Ilaria Balbo, Brittany L Phillips, Min Li, Jessica Estrada, Marianna Zazhytska, Yow-Tyng Yeh, Lia Min, Elizabeth Rafikian, Elizabeth Valenzuela, Brian Joseph, Tulsi Patel, Dmytro Ustienenko, Helene Lovett, Huijuan Feng, Xiaojian Wang, Susan Brenner Morton, Chyuan Sheng […]


Continue.. A neuron type-specific microexon in Ank3/ankyrin-G modulates calcium activity and neuronal excitability

The Converging Effects of Different Categories of Antidepressants on the Brain: A Systematic Meta-Analysis of Public Transcriptional Profiling Data from the Hippocampus and Cortex

Kavli Affiliate: René Hen | Authors: Eva M Geoghegan, Megan Hastings Hagenauer, Erin Hernandez, Sophia Espinoza, Elizabeth I Flandreau, Phi T. Nguyen, Adrienne N. Santiago, Mubashshir Ra’eed Bhuiyan, Sophie Mensch, Stanley J. Watson, Jr., Huda Akil and René Hen | Summary: Background Depression can be treated with traditional antidepressant pharmaceuticals targeting monoaminergic function, as well […]


Continue.. The Converging Effects of Different Categories of Antidepressants on the Brain: A Systematic Meta-Analysis of Public Transcriptional Profiling Data from the Hippocampus and Cortex

VIP-OT: Dissecting Single-Cell Biochemical State Dynamics under Perturbation via Vibrational Painting and Optimal Transport

Kavli Affiliate: Wei Min | Authors: Xuemeng Li, Stefan G. Stark, Xinwen Liu, Mian Wei, Zhilun Zhao, Jianhuan Qi, Xingjian Chen, Thai Nam Son Dang, Yinghan Wu, Ke Zhang, Wei Min and Jian Shu | Summary: Dissecting the heterogeneous response of individual cells towards genetic and chemical perturbations is central to understanding the dynamic functions […]


Continue.. VIP-OT: Dissecting Single-Cell Biochemical State Dynamics under Perturbation via Vibrational Painting and Optimal Transport

Learning decouples accuracy and reaction time for rapid decisions in a transitive inference task

Kavli Affiliate: Vincent Ferrera | Authors: Fabian A Munoz Silva, Greg Jensen, Maxwell Shinn, Yelda Alkan, John Murray, Herbert Terrace and Vincent P Ferrera | Summary: Transitive inference (TI) is a cognitive process in which decisions are guided by internal representations of abstract relationships. While the mechanisms underlying transitive learning have been well studied, the […]


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DENDRO: Recovery and denoising of whole-tree dendritic voltage from 2D voltage movies

Kavli Affiliate: Liam Paninski | Authors: Benjamin Antin, Pojeong Park, Amol Praveen Pasarkar, Utku Ferah, Chase King, Adam Ezra Cohen and Liam Paninski | Summary: The ability to image voltage at high spatiotemporal resolution across an entire dendritic tree would represent a major advance in systems and circuit neuroscience. Recent advances in genetically encoded voltage […]


Continue.. DENDRO: Recovery and denoising of whole-tree dendritic voltage from 2D voltage movies

Shared striatal neurons exhibit context-specific dynamics for internally and externally driven actions

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Darcy Peterka and Rui Costa | Authors: Jan L. Klee, Sulekh Fernando-Peiris, Sahil Suresh, Ines Rodrigues-Vaz, Darcy S Peterka, Rui M. Costa, Vivek R. Athalye and Tanya Sippy | Summary: Animals can initiate movements either in response to external cues […]


Continue.. Shared striatal neurons exhibit context-specific dynamics for internally and externally driven actions