Generalizable and explainable prediction of potential miRNA-disease associations based on heterogeneous graph learning

Posted by klaurent UCAS

Kavli Affiliate: Yi Zhou | First 5 Authors: Yi Zhou, Meixuan Wu, Chengzhou Ouyang, Min Zhu, | Summary: Biomedical research has revealed the crucial role of miRNAs in the progression of many diseases, and computational prediction methods are increasingly proposed for assisting biological experiments to verify miRNA-disease associations (MDAs). However, the generalizability and explainability are […]


Continue.. Generalizable and explainable prediction of potential miRNA-disease associations based on heterogeneous graph learning

Generalizable prediction of potential miRNA-disease associations based on heterogeneous graph learning

Posted by klaurent UCAS

Kavli Affiliate: Yi Zhou | First 5 Authors: Yi Zhou, Meixuan Wu, Chengzhou Ouyang, Xinyi Wang, Min Zhu | Summary: Biomedical studies have revealed the crucial role of miRNAs in the progression of many diseases, and computational prediction methods are increasingly proposed for assisting biological experiments to verify miRNA-disease associations (MDAs). The generalizability is a […]


Continue.. Generalizable prediction of potential miRNA-disease associations based on heterogeneous graph learning

Removing direct photocurrent artifacts in optogenetic connectivity mapping data via constrained matrix factorization

Posted by klaurent Columbia

Kavli Affiliate: Liam Paninski | Authors: Benjamin Antin, Masato Sadahiro, Marta Gajowa, Marcus A. Triplett, Hillel Adesnik and Liam Paninski | Summary: Monosynaptic connectivity mapping is crucial for building circuit-level models of neural computation. Two-photon optogenetic stimulation, when combined with whole-cell recordings, has the potential to map monosynaptic connectivity at an unprecedented scale. However, optogenetic […]


Continue.. Removing direct photocurrent artifacts in optogenetic connectivity mapping data via constrained matrix factorization

Large Language Models as Superpositions of Cultural Perspectives

Posted by klaurent MIT

Kavli Affiliate: Peter Ford | First 5 Authors: Grgur Kovač, Masataka Sawayama, Rémy Portelas, Cédric Colas, Peter Ford Dominey | Summary: Large Language Models (LLMs) are often misleadingly recognized as having a personality or a set of values. We argue that an LLM can be seen as a superposition of perspectives with different values and […]


Continue.. Large Language Models as Superpositions of Cultural Perspectives

Large Language Models as Superpositions of Cultural Perspectives

Posted by klaurent MIT

Kavli Affiliate: Peter Ford | First 5 Authors: Grgur Kovač, Masataka Sawayama, Rémy Portelas, Cédric Colas, Peter Ford Dominey | Summary: Large Language Models (LLMs) are often misleadingly recognized as having a personality or a set of values. We argue that an LLM can be seen as a superposition of perspectives with different values and […]


Continue.. Large Language Models as Superpositions of Cultural Perspectives

Sensitivity Analysis for Unmeasured Confounding in Medical Product Development and Evaluation Using Real World Evidence

Posted by klaurent Berkeley

Kavli Affiliate: Xiang Zhang | First 5 Authors: Peng Ding, Yixin Fang, Doug Faries, Susan Gruber, Hana Lee | Summary: The American Statistical Association Biopharmaceutical Section (ASA BIOP) working group on real-world evidence (RWE) has been making continuous, extended effort towards a goal of supporting and advancing regulatory science with respect to non-interventional, clinical studies […]


Continue.. Sensitivity Analysis for Unmeasured Confounding in Medical Product Development and Evaluation Using Real World Evidence

Hue selectivity from recurrent circuitry in Drosophila

Posted by klaurent Columbia

Kavli Affiliate: Rudy Behnia | Authors: Matthias P Christenson, Alvaro Sanz Diez, Sarah L Heath, Maia Saavedra-Weisenhaus, Atsuko Adashi, LF Abbott and Rudy Behnia | Summary: A universal principle of sensory perception is the progressive transformation of sensory information from broad non-specific signals to stimulus-selective signals that form the basis of perception. To perceive color, […]


Continue.. Hue selectivity from recurrent circuitry in Drosophila

The UV Continuum Slopes of Early Star-Forming Galaxies in JADES

Posted by klaurent Cambridge

Kavli Affiliate: Roberto Maiolino | First 5 Authors: Michael W. Topping, Daniel P. Stark, Ryan Endsley, Lily Whitler, Kevin Hainline | Summary: The power-law slope of the rest-UV continuum ($f_{lambda}proptolambda^{beta}$) is a key metric of early star forming galaxies, providing one of our only windows into the stellar populations and physical conditions of $z>10$ galaxies. […]


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Biexcitons are bound in CsPbBr3 Perovskite Nanocrystals

Posted by klaurent Berkeley

Kavli Affiliate: David T. Limmer | First 5 Authors: Yoonjae Park, David T. Limmer, , , | Summary: We study the energetics of quasi-particle excitations in CsPbBr3 perovskite nanocrystals using path integral molecular dynamics simulations. Employing detailed molecular models, we elucidate the interplay of anharmonic lattice degrees of freedom, dielectric confinement, and electronic correlation on […]


Continue.. Biexcitons are bound in CsPbBr3 Perovskite Nanocrystals