High-resolution, large field-of-view label-free imaging via aberration-corrected, closed-form complex field reconstruction

Kavli Affiliate: Changhuei Yang | First 5 Authors: Ruizhi Cao, Cheng Shen, Changhuei Yang, , | Summary: Computational imaging methods empower modern microscopy with the ability of producing high-resolution, large field-of-view, aberration-free images. One of the dominant computational label-free imaging methods, Fourier ptychographic microscopy (FPM), effectively increases the spatial-bandwidth product of conventional microscopy by using […]


Continue.. High-resolution, large field-of-view label-free imaging via aberration-corrected, closed-form complex field reconstruction

Contextual Biasing of Named-Entities with Large Language Models

Kavli Affiliate: Zeeshan Ahmed | First 5 Authors: Chuanneng Sun, Zeeshan Ahmed, Yingyi Ma, Zhe Liu, Yutong Pang | Summary: This paper studies contextual biasing with Large Language Models (LLMs), where during second-pass rescoring additional contextual information is provided to a LLM to boost Automatic Speech Recognition (ASR) performance. We propose to leverage prompts for […]


Continue.. Contextual Biasing of Named-Entities with Large Language Models

Dark Energy Survey Year 6 Results: Intra-Cluster Light from Redshift 0.2 to 0.5

Kavli Affiliate: Eli S. Rykoff | First 5 Authors: Yuanyuan Zhang, Jesse B. Golden-Marx, Ricardo L. C. Ogando, Brian Yanny, Eli S. Rykoff | Summary: Using the full six years of imaging data from the Dark Energy Survey, we study the surface brightness profiles of galaxy cluster central galaxies and intra-cluster light. We apply a […]


Continue.. Dark Energy Survey Year 6 Results: Intra-Cluster Light from Redshift 0.2 to 0.5

The black hole mass metallicity relation and insights into galaxy quenching

Kavli Affiliate: Roberto Maiolino | First 5 Authors: William M. Baker, Roberto Maiolino, Asa F. L. Bluck, Francesco Belfiore, Mirko Curti | Summary: One of the most important questions in astrophysics is what causes galaxies to stop forming stars. Previous studies have shown a tight link between quiescence and black hole mass. Other studies have […]


Continue.. The black hole mass metallicity relation and insights into galaxy quenching

Amplifying Non-Resonant Production of Dark Sector Particles in Scattering Dominance Regime

Kavli Affiliate: Jia Liu | First 5 Authors: Mingxuan Du, Jia Liu, Xiao-Ping Wang, Tianhao Wu, | Summary: We investigate the enhancement of dark sector particle production within the scattering dominant regime. These particles typically exhibit a slight mixing with Standard Model particles through various portals, allowing for their generation through in-medium oscillation from Standard […]


Continue.. Amplifying Non-Resonant Production of Dark Sector Particles in Scattering Dominance Regime

The mechanism of Gαq regulation of PLCβ3-catalyzed PIP2 hydrolysis.

Kavli Affiliate: Roderick MacKinnon | Authors: Maria Elizabeth Falzone and Roderick MacKinnon | Summary: PLCβ enzymes cleave PIP2 producing IP3 and DAG. PIP2 modulates the function of many ion channels, while IP3 and DAG regulate intracellular Ca2+ levels and protein phosphorylation by protein kinase C, respectively. PLCb enzymes are under the control of GPCR signaling […]


Continue.. The mechanism of Gαq regulation of PLCβ3-catalyzed PIP2 hydrolysis.

Effort cost of reaching prompts vigor reduction in older adults

Kavli Affiliate: Reza Shadmehr | Authors: Erik M. Summerside, Robert J Courter, Reza Shadmehr and Alaa A. Ahmed | Summary: As people age, they move slower. Is age-related reduction in vigor a reflection of a reduced valuation of reward by the brain, or a consequence of increased effort costs by the muscles? Here, we quantified […]


Continue.. Effort cost of reaching prompts vigor reduction in older adults

Spatiotemporal development of growth and death zones in expanding bacterial colonies driven by emergent nutrient dynamics

Kavli Affiliate: David Kleinfeld | Authors: Harish Kannan, Paul Sun, Tolga Çağlar, Pantong Yao, Brian R Taylor, Kinshuk Sahu, Daotong Ge, Matteo Mori, Mya Warren, David Kleinfeld, JiaJia Dong, Bo Li and Terence Hwa | Summary: Bacterial colony growth on hard agar is commonplace in microbiology; yet, what occurs inside a growing colony is complex […]


Continue.. Spatiotemporal development of growth and death zones in expanding bacterial colonies driven by emergent nutrient dynamics

Learning chemical sensitivity reveals mechanisms of cellular response

Kavli Affiliate: Michael Keiser | Authors: William J. Connell, Kristle Garcia, Hani Goodarzi and Michael J. Keiser | Summary: Chemical probes interrogate disease mechanisms at the molecular level by linking genetic changes to observable traits. However, comprehensive chemical screens in diverse biological models are impractical. To address this challenge, we developed ChemProbe, a model that […]


Continue.. Learning chemical sensitivity reveals mechanisms of cellular response