A Biophysical Basis for Learning and Transmitting Sensory Predictions

Kavli Affiliate: Larry Abbott, Nathaniel Sawtell | Authors: Salomon Zev Muller, Larry F Abbott and Nathaniel B Sawtell | Summary: Abstract Homeostatic (anti-Hebbian) forms of synaptic are effective at eliminating “prediction errors” that signal the differences between predicted and actual sensory input. However, such mechanisms appear to preclude the possibility of transmitting the resulting predictions […]


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Preservation of prehearing spontaneous activity enables early auditory system development in deaf mice

Kavli Affiliate: Dwight Bergles, Patrick Kanold | Authors: Calvin J Kersbergen, Travis A Babola, Patrick O Kanold and Dwight E Bergles | Summary: ABSTRACT Intrinsically generated neural activity propagates through the developing auditory system to promote maturation and refinement of sound processing circuits prior to hearing onset. This early patterned activity is induced by non-sensory […]


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Stochastic thermodynamic bounds on logical circuit operation

Kavli Affiliate: David T. Limmer | First 5 Authors: Phillip Helms, David T. Limmer, , , | Summary: Using a thermodynamically consistent, mesoscopic model for modern complementary metal-oxide-semiconductor transistors, we study an array of logical circuits and explore how their function is constrained by recent thermodynamic uncertainty relations when operating near thermal energies. For a […]


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Gate-tunable heavy fermions in a moiré Kondo lattice

Kavli Affiliate: Jie Shan | First 5 Authors: Wenjin Zhao, Bowen Shen, Zui Tao, Zhongdong Han, Kaifei Kang | Summary: The Kondo lattice, describing a matrix of local magnetic moments coupled via spin-exchange interactions to itinerant conduction electrons, is a prototype of strongly correlated quantum matter. Traditionally, Kondo lattices are realized in intermetallic compounds containing […]


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CodeEditor: Learning to Edit Source Code with Pre-trained Models

Kavli Affiliate: Zhuo Li | First 5 Authors: Jia Allen Li, Ge Li, Zhuo Li, Zhi Jin, Xing Hu | Summary: Developers often perform repetitive code editing activities for various reasons (e.g., code refactoring) during software development. Pre-trained code editing models have achieved the state-of-the-art (SOTA) results. Pre-trained models are first pre-trained with pre-training tasks […]


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CodeEditor: Learning to Edit Source Code with Pre-trained Models

Kavli Affiliate: Zhuo Li | First 5 Authors: Jia Li, Ge Li, Zhuo Li, Zhi Jin, Xing Hu | Summary: Developers often perform repetitive code editing activities for various reasons (e.g., code refactoring) during software development. Pre-trained code editing models have achieved the state-of-the-art (SOTA) results. Pre-trained models are first pre-trained with pre-training tasks and […]


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The BRAIN Initiative Cell Census Data Ecosystem: A User’s Guide

Kavli Affiliate: Michael Miller | Authors: BICCN Data Ecosytem Collaboration, Michael J Hawrylycz, Maryann E Martone, Patrick R Hof, Ed S Lein, Aviv Regev, Giorgio A. A Ascoli, Jan G Bjaalie, Hong-Wei Dong, Satrajit S Ghosh, Jesse Gillis, Ronna Hertzano, David R Haynor, Yongsoo Kim, Yufeng Liu, Jeremy A Miller, Partha P Mitra, Eran Mukamel, […]


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Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids

Kavli Affiliate: Vy Thuy Nguyen | Authors: Kim Vy Nguyen Ngoc, Somesh Sai, Yesl Jun, R. Hugh F. Bender, Vira Kravets, Han Zhu, Christopher J Hatch, Michael Schlichting, Roberto Gaetani, Medhavi Mallick, Stephanie J Hachey, Karen Christman, Steven Carl George, Christopher C Hughes and Maike Sander | Summary: Abstract Blood vessels play a critical role […]


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Spin hydrodynamic generation in unsteady flows

Kavli Affiliate: Mamoru Matsuo | First 5 Authors: Takumi Funato, Mamoru Matsuo, , , | Summary: We theoretically investigate a spin-mediated conversion from fluid dynamics to voltage, known as spin hydrodynamic generation (SHDG), in oscillatory and transient unsteady flows. We consider unsteady flows of liquid metal between two parallel infinite planes and then calculate its […]


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Palmitoylation regulates neuropilin-2 localization and function in cortical neurons and conveys specificity to semaphorin signaling via palmitoyl acyltransferases

Kavli Affiliate: Alex Kolodkin | Authors: Eleftheria Koropouli, Qiang Wang, Rebeca Mejias-Estevez, Randal Hand, Tao Wang, David D Ginty and Alex L Kolodkin | Summary: ABSTRACT Secreted semaphorin 3F (Sema3F) and semaphorin 3A (Sema3A) exhibit remarkably distinct effects on deep layer excitatory cortical pyramidal neurons; Sema3F mediates dendritic spine pruning, whereas Sema3A promotes the elaboration […]


Continue.. Palmitoylation regulates neuropilin-2 localization and function in cortical neurons and conveys specificity to semaphorin signaling via palmitoyl acyltransferases