Brain substates induced by DMT relate to sympathetic output and meaningfulness of the experience

Kavli Affiliate: Adam Gazzaley | Authors: Lorenzo Pasquini, Alexander Simon, Courtney Gallen, Hannes Kettner, Leor Roseman, Adam Gazzaley, Robin Carhart-Harris and Christopher Timmermann | Summary: N,N-Dimethyltryptamine (DMT) is a serotonergic psychedelic, known to rapidly induce short-lasting alterations in conscious experience, characterized by a profound and immersive sense of physical transcendence alongside rich and vivid auditory […]


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SPHEREx: NASA’s Near-Infrared Spectrophotmetric All-Sky Survey

Kavli Affiliate: Lindsey Bleem | First 5 Authors: Brendan P. Crill, Michael Werner, Rachel Akeson, Matthew Ashby, Lindsey Bleem | Summary: SPHEREx, the Spectro-Photometer for the History of the Universe, Epoch of Reionization, and ices Explorer, is a NASA MIDEX mission planned for launch in 2024. SPHEREx will carry out the first all-sky spectral survey […]


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Combined Pre-Supernova Alert System with Kamland and Super-Kamiokande

Kavli Affiliate: Mark Hartz | First 5 Authors: KamLAND, Super-Kamiokande Collaborations, :, Seisho Abe, Minori Eizuka | Summary: Preceding a core-collapse supernova, various processes produce an increasing amount of neutrinos of all flavors characterized by mounting energies from the interior of massive stars. Among them, the electron antineutrinos are potentially detectable by terrestrial neutrino experiments […]


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Cellular and Molecular Basis of Leptin Resistance

Kavli Affiliate: Jeffrey M. Friedman | Authors: Bowen Tan, Kristina Hedbacker, Leah Kelly, Zhaoyue Zhang, Ji-Dung Luo, Joshua D. Rabinowitz and Jeffrey M. Friedman | Summary: Obese humans and diet induced obese mice (DIO) have high leptin levels and fail to respond to the exogenous hormone suggesting that obesity is caused by leptin resistance, the […]


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Correlation decoupling of Casimir interaction in an electrolyte driven by external electric fields

Kavli Affiliate: Rudolf Podgornik | First 5 Authors: Guangle Du, David S. Dean, Bing Miao, Rudolf Podgornik, | Summary: It has been established for a long time that the long range van der Waals or thermal Casimir interaction between two semi-infinite dielectrics separated by a distance $H$ is screened by an intervening electrolyte. Here we […]


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A mathematical theory of relational generalization in transitive inference

Kavli Affiliate: Vincent Ferrera | Authors: Samuel Lippl, Kenneth Kay, Greg Jensen, Vincent P. Ferrera and L.F. Abbott | Summary: Humans and animals routinely infer relations between different items or events and generalize these relations to novel combinations of items (“compositional generalization”). This allows them to respond appropriately to radically novel circumstances and is fundamental […]


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Small extracellular vesicles promote stiffness-mediated metastasis

Kavli Affiliate: Denis Wirtz | Authors: Alexandra Sneider, Ying Liu, Bartholomew Starich, Wenxuan Du, Carolyn Marar, Najwa Faqih, Gabrielle E Ciotti, Joo Ho Kim, Sejal Krishnan, Salma Ibrahim, Muna Igboko, Alexus Locke, Daniel M Lewis, Hanna Hong, Michelle Karl, Raghav Vij, Gabriella C Russo, Praful R Nair, Estibaliz Gómez-de-Mariscal, Mehran Habibi, Arrate Munoz-Barrutia, Luo Gu, […]


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Continuous Bump Attractor Networks Require Explicit Error Coding for Gain Recalibration

Kavli Affiliate: James Knierim | Authors: Gorkem Secer, James J. Knierim and Noah J. Cowan | Summary: Representations of continuous variables are crucial to create internal models of the external world. A prevailing model of how the brain maintains these representations is given by continuous bump attractor networks (CBANs) in a broad range of brain […]


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Gene count normalization in single-cell imaging-based spatially resolved transcriptomics

Kavli Affiliate: Jean Fan | Authors: Lyla Atta, Kalen Clifton, Manjari Anant and Jean Fan | Summary: Recent advances in imaging-based spatially resolved transcriptomics (im-SRT) technologies now enable high-throughput profiling of targeted genes and their locations in fixed tissues. Normalization of gene expression data is often needed to account for technical factors that may confound […]


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Multiple objects evoke fluctuating responses in several regions of the visual pathway

Kavli Affiliate: Winrich Freiwald | Authors: Meredith N Schmehl, Valeria C Caruso, Yunran Chen, Na Young Jun, Shawn M Willett, Jeff T Mohl, Douglas A Ruff, Marlene R Cohen, Akinori Ebihara, Winrich Freiwald, Surya T Tokdar and Jennifer M Groh | Summary: How neural representations preserve information about multiple stimuli is mysterious. Because tuning of […]


Continue.. Multiple objects evoke fluctuating responses in several regions of the visual pathway