EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis

Kavli Affiliate: Jose Suarez Lopez | Authors: Sukanya Chakraborty, Aaqib M. Bhat, Insha Mushtaq, Haitao Luan, Achyuth Kalluchi, Sameer Mirza, Matthew D. Storck, Nagendra Chaturvedi, Jose Antonio Lopez-Guerreo, Antonio Llombart-Bosch, Isidro Machado, Jane L. Meza, Gargi Ghosal, Donald W. Coulter, Jordan M. Rowley, Vimla Band, Bhopal C. Mohapatra and Hamid Band | Summary: We previously […]


Continue.. EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis

The Eighteenth Data Release of the Sloan Digital Sky Surveys: Targeting and First Spectra from SDSS-V

Kavli Affiliate: Yingjie Peng | First 5 Authors: Andrés Almeida, Scott F. Anderson, Maria Argudo-Fernández, Carles Badenes, Kat Barger | Summary: The eighteenth data release of the Sloan Digital Sky Surveys (SDSS) is the first one for SDSS-V, the fifth generation of the survey. SDSS-V comprises three primary scientific programs, or "Mappers": Milky Way Mapper […]


Continue.. The Eighteenth Data Release of the Sloan Digital Sky Surveys: Targeting and First Spectra from SDSS-V

Solaris: A Focused Solar Polar Discovery-class Mission to achieve the Highest Priority Heliophysics Science Now

Kavli Affiliate: J. Todd Hoeksema | First 5 Authors: Donald M. Hassler, Sarah E Gibson, Jeffrey S Newmark, Nicholas A. Featherstone, Lisa Upton | Summary: Solaris is a transformative Solar Polar Discovery-class mission concept to address crucial outstanding questions that can only be answered from a polar vantage. Solaris will image the Sun’s poles from […]


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From X-rays to physical parameters: a comprehensive analysis of thermal tidal disruption event X-ray spectra

Kavli Affiliate: Dheeraj Pasham | First 5 Authors: Andrew Mummery, Thomas Wevers, Richard Saxton, Dheeraj Pasham, | Summary: We perform a comprehensive analysis of a population of 19 X-ray bright tidal disruption events (TDEs), fitting their X-ray spectra with a new, physically self consistent, relativistic accretion disc model. Not all of the TDEs inhabit regions […]


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Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels

Kavli Affiliate: Michael Keiser | Authors: Daniel R. Wong, Shino D. Magaki, Harry V. Vinters, William H. Yong, Edwin S. Monuki, Christopher K. Williams, Alessandra C. Martini, Charles DeCarli, Chris Khacherian, John P. Graff, Brittany N. Dugger and Michael J. Keiser | Summary: Precise, scalable, and quantitative evaluation of whole slide images is crucial in […]


Continue.. Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels

Grapevine scion gene expression is driven by rootstock and environment interaction

Kavli Affiliate: Angela Wu | Authors: Zachary N Harris, Julia E Pratt, Laszlo G Kovacs, Laura L Klein, Misha T Kwasniewski, Jason P Londo, Angela Wu and Allison J Miller | Summary: BACKGROUND Grafting is a horticultural practice used widely across woody perennial crop species to fuse together the root and shoot system of two […]


Continue.. Grapevine scion gene expression is driven by rootstock and environment interaction

The neural activity of auditory conscious perception

Kavli Affiliate: Hal Blumenfeld | Authors: Kate L. Christison-Lagay, Noah C. Freedman, Christopher Micek, Aya Khalaf, Sharif I. Kronemer, Mariana M. Gusso, Lauren Kim, Sarit Forman, Julia Ding, Mark Aksen, Ahmad Abdel-Aty, Hunki Kwon, Noah Markowitz, Erin Yeagle, Elizabeth Espinal, Jose Herrero, Stephan Bickel, James Young, Ashesh Mehta, Kun Wu, Jason Gerrard, Eyiyemisi Damisah, Dennis […]


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End Binding protein 1 promotes specific motor-cargo association in the cell body prior to axonal delivery of Dense Core Vesicles

Kavli Affiliate: Pietro DeCamilli, Kenneth Miller | Authors: Junhyun Park, Kenneth G. Miller, Pietro De Camilli and Shaul Yogev | Summary: Axonal transport is key to neuronal function. Efficient transport requires specific motor-cargo association in the soma, yet the mechanisms regulating this early step remain poorly understood. We found that EBP-1, the C. elegans ortholog […]


Continue.. End Binding protein 1 promotes specific motor-cargo association in the cell body prior to axonal delivery of Dense Core Vesicles

Bacterial meningitis in the early postnatal mouse studied at single-cell resolution

Kavli Affiliate: Jeremy Nathans | Authors: Jie Wang, Amir Rattner and Jeremy Nathans | Summary: Bacterial meningitis is a major cause of morbidity and mortality, especially among infants and the elderly. Here we study mice to assess the response of each of the major meningeal cell types to early postnatal E. coli infection using single […]


Continue.. Bacterial meningitis in the early postnatal mouse studied at single-cell resolution