OptMetaOpenFOAM: Large Language Model Driven Chain of Thought for Sensitivity Analysis and Parameter Optimization based on CFD

Kavli Affiliate: Long Zhang | First 5 Authors: Yuxuan Chen, Long Zhang, Xu Zhu, Hua Zhou, Zhuyin Ren | Summary: Merging natural language interfaces with computational fluid dynamics (CFD) workflows presents transformative opportunities for both industry and research. In this study, we introduce OptMetaOpenFOAM – a novel framework that bridges MetaOpenFOAM with external analysis and […]


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ReaderLM-v2: Small Language Model for HTML to Markdown and JSON

Kavli Affiliate: Feng Wang | First 5 Authors: Feng Wang, Zesheng Shi, Bo Wang, Nan Wang, Han Xiao | Summary: We present ReaderLM-v2, a compact 1.5 billion parameter language model designed for efficient web content extraction. Our model processes documents up to 512K tokens, transforming messy HTML into clean Markdown or JSON formats with high […]


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Beyond Visibility Limits: A DRL-Based Navigation Strategy for Unexpected Obstacles

Kavli Affiliate: Biao Huang | First 5 Authors: Mingao Tan, Shanze Wang, Biao Huang, Zhibo Yang, Rongfei Chen | Summary: Distance-based reward mechanisms in deep reinforcement learning (DRL) navigation systems suffer from critical safety limitations in dynamic environments, frequently resulting in collisions when visibility is restricted. We propose DRL-NSUO, a novel navigation strategy for unexpected […]


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Mapping the ISR Landscape in Cognitive Disorders via single-cell multi-omics

Kavli Affiliate: Peter Walter | Authors: Kristof Torkenczy, Lucas C Reineke, Sean W Dooling, Benjamin W Henderson, Daniel Itzhak, Benjamin Yang, Dongze He, Richard M Myers, Peter Walter, Stefka Tyanova and Mauro Costa-Mattioli | Summary: Persistent activation of the integrated stress response (ISR) is a major driver of cognitive decline in both neurodevelopmental and neurodegenerative […]


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Output Length Effect on DeepSeek-R1’s Safety in Forced Thinking

Kavli Affiliate: Zhuo Li | First 5 Authors: Xuying Li, Zhuo Li, Yuji Kosuga, Victor Bian, | Summary: Large Language Models (LLMs) have demonstrated strong reasoning capabilities, but their safety under adversarial conditions remains a challenge. This study examines the impact of output length on the robustness of DeepSeek-R1, particularly in Forced Thinking scenarios. We […]


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Output Length Effect on DeepSeek-R1’s Safety in Forced Thinking

Kavli Affiliate: Zhuo Li | First 5 Authors: Xuying Li, Zhuo Li, Yuji Kosuga, Victor Bian, | Summary: Large Language Models (LLMs) have demonstrated strong reasoning capabilities, but their safety under adversarial conditions remains a challenge. This study examines the impact of output length on the robustness of DeepSeek-R1, particularly in Forced Thinking scenarios. We […]


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ATMO: An Aerially Transforming Morphobot for Dynamic Ground-Aerial Transition

Kavli Affiliate: Morteza Gharib | First 5 Authors: Ioannis Mandralis, Reza Nemovi, Alireza Ramezani, Richard M. Murray, Morteza Gharib | Summary: Designing ground-aerial robots is challenging due to the increased actuation requirements which can lead to added weight and reduced locomotion efficiency. Morphobots mitigate this by combining actuators into multi-functional groups and leveraging ground transformation […]


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Collective Neutrino Oscillations in Three Flavors on Qubit and Qutrit Processors

Kavli Affiliate: Irfan Siddiqi | First 5 Authors: Luca Spagnoli, Noah Goss, Alessandro Roggero, Ermal Rrapaj, Michael J. Cervia | Summary: Collective neutrino flavor oscillations are of primary importance in understanding the dynamic evolution of core-collapse supernovae and subsequent terrestrial detection, but also among the most challenging aspects of numerical simulations. This situation is complicated […]


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Deconvolution to restore cryo-EM maps with anisotropic resolution

Kavli Affiliate: Yifan Cheng | Authors: Junrui Li, Yifei chen, Shawn Zheng, Angus McDonald, John W. Sedat, David A. Agard and Yifan Cheng | Summary: With technological advancements in recent years, single particle cryogenic electron microscopy (cryo-EM) has become a major methodology for structural biology. Structure determination by single particle cryo-EM is premised on randomly […]


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Development of an image-guided non-vitrectomy subretinal access approach for trans-scleral cell and gene therapy delivery

Kavli Affiliate: Jin Kang | Authors: Mandeep S Singh, Shoujing Guo, Christopher B Toomey, Minda M McNally, Sarah Harris-Bookman, Kang V Li, Dzhalal Agakishiev, Shuwen Wei, Soohyun Lee, Kathleen Perrino, Kevin C Wolfe and Jin Kang | Summary: Purpose Regenerative therapies for retinal diseases include cell and gene therapy modalities that are targeted to the […]


Continue.. Development of an image-guided non-vitrectomy subretinal access approach for trans-scleral cell and gene therapy delivery