Neuromuscular Signals Shape Fatigue and Effort-Based Decision-Making in Humans

Kavli Affiliate: Vikram Chib | Authors: Agostina Casamento-Moran, Aram Kim, Joonhee Leo Lee and Vikram S. Chib | Summary: Physical fatigue influences our willingness to undertake effortful actions, yet the physiological signals driving this process are not well understood. We created a biofeedback paradigm to distinguish the effects of reduced muscle-force capacity from compensatory increases […]


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Worlds Next Door. IV. Mapping the Late Stages of Giant Planet Evolution with a Precise Dynamical Mass and Luminosity for $ε$ Ind Ab

Kavli Affiliate: Dimitri Mawet| Summary:We present new JWST/NIRCam 4-5 $μ$m (F410M, F430M) and JWST/MIRI 18-25 $μ$m (F1800W, F2100W, F2550W) imaging detections of the nearby (3.6 pc) cold (275 K) gas giant exoplanet $ε$ Ind Ab. The F2550W detection of $ε$ Ind Ab constitutes the longest wavelength image of an exoplanet acquired to date. Combining three […]


Continue.. Worlds Next Door. IV. Mapping the Late Stages of Giant Planet Evolution with a Precise Dynamical Mass and Luminosity for $ε$ Ind Ab

Worlds Next Door. IV. Mapping the Late Stages of Giant Planet Evolution with a Precise Dynamical Mass and Luminosity for $ε$ Ind Ab

Kavli Affiliate: Dimitri Mawet| Summary:We present new JWST/NIRCam 4-5 $μ$m (F410M, F430M) and JWST/MIRI 18-25 $μ$m (F1800W, F2100W, F2550W) imaging detections of the nearby (3.6 pc) cold (275 K) gas giant exoplanet $ε$ Ind Ab. The F2550W detection of $ε$ Ind Ab constitutes the longest wavelength image of an exoplanet acquired to date. Combining three […]


Continue.. Worlds Next Door. IV. Mapping the Late Stages of Giant Planet Evolution with a Precise Dynamical Mass and Luminosity for $ε$ Ind Ab

The extreme diversity of retinal amacrine cells has deep evolutionary roots

Kavli Affiliate: Seth Blackshaw | Authors: Dario Tommasini, Aboozar Monavarfeshani, Vishruth Dinesh, Joshua Hahn, Jared Tangeman, Olivier Marre, Seth Blackshaw, Teresa Puthussery, Joshua Sanes and Karthik Shekhar | Summary: Amacrine cells (ACs) comprise a heterogeneous class of inhibitory neurons in the vertebrate retina, exhibiting morphological and functional complexity rivaling that of cortical interneurons. Here, we […]


Continue.. The extreme diversity of retinal amacrine cells has deep evolutionary roots

RhoGEF12 regulates endosomal SORL1-retromer and its inhibition is therapeutic in human neuronal models of Alzheimer’s disease

Kavli Affiliate: Scott Small | Authors: Yasir H. Qureshi, Charles A. Williams, Istvan Hajdu, Suvarnambiga Kannan, Ananya Govindarajan, Barbara Vegh, Gregory A. Petsko, Jessica E. Young, Peter Zavodszky and Scott A. Small | Summary: The interaction of the endosomal sorting protein SORL1 with the retromer complex at endosomal membranes controls a recycling pathway whose dysfunction […]


Continue.. RhoGEF12 regulates endosomal SORL1-retromer and its inhibition is therapeutic in human neuronal models of Alzheimer’s disease

End-to-end optimisation of HEP triggers

Kavli Affiliate: David W. Miller | Summary:High-energy physics experiments face extreme data rates, requiring real-time trigger systems to reduce event throughput while preserving sensitivity to rare processes. Trigger systems are typically constructed as modular chains of sequentially optimised algorithms, including machine learning models. Each algorithm is optimised for a specific local objective with no guarantee […]


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Correlation between nuclear isospin asymmetry and $α$-particle preformation probability for superheavy nuclei from a Bayesian inference

Kavli Affiliate: Wei Gao| Summary:In the study of $α$ decay within the superheavy nuclear region ($Z geq 90$ and $N geq 140$), the $α$-particle preformation probability $P_α$ serves as a crucial physical quantity linking nuclear structure to decay observables. We introduce a phenomenological model incorporating the decay energy $Q_α$, mass number $A$, orbital angular momentum […]


Continue.. Correlation between nuclear isospin asymmetry and $α$-particle preformation probability for superheavy nuclei from a Bayesian inference

Correlation between nuclear isospin asymmetry and $α$-particle preformation probability for superheavy nuclei from a Bayesian inference

Kavli Affiliate: Wei Gao| Summary:In the study of $α$ decay within the superheavy nuclear region ($Z geq 90$ and $N geq 140$), the $α$-particle preformation probability $P_α$ serves as a crucial physical quantity linking nuclear structure to decay observables. We introduce a phenomenological model incorporating the decay energy $Q_α$, mass number $A$, orbital angular momentum […]


Continue.. Correlation between nuclear isospin asymmetry and $α$-particle preformation probability for superheavy nuclei from a Bayesian inference

Bayesian neural network with autoencoder for model-based description of $α$-particle preformation factor

Kavli Affiliate: Wei Gao| Summary:$α$ decay is an important probe for studying the structure of heavy and superheavy nuclei, in which the $α$-particle preformation ($P_α$) is a key physical quantity for describing decay half-lives. This work develops a hybrid framework that integrates Bayesian neural networks with autoencoder (BNN-Auto), combined with the cosh potential (CPT), to […]


Continue.. Bayesian neural network with autoencoder for model-based description of $α$-particle preformation factor

Centrifugal-corrected harmonic oscillator model for spherical proton emitters

Kavli Affiliate: Wei Gao| Summary:In the present work, we propose an improved harmonic oscillator model to systematically evaluate the proton radioactivity half-lives in spherical nuclei, incorporating centrifugal potential effects. By fitting the experimental data, the centrifugal parameter $d = 0.143$ for the correction term $dl(l+1)$ and nuclear potential depth $V_0 = 62.4$ MeV are obtained. […]


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