A Three-dimensional Analytical Framework for Retinal Microvasculature Reveals Layer-associated Vulnerability in Development and Neovascular Remodeling

Posted by dbos UCSF

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Xin Duan | Authors: Wenhao Shang, Guiying Hong, William E Keller, Ryan A Morton, Pierre Zeboulon, Toma Kenichi, Xin Duan, Douglas B Gould and Tyson N Kim | Summary: The neurosensory retina is one of the most metabolically active tissues […]


Continue.. A Three-dimensional Analytical Framework for Retinal Microvasculature Reveals Layer-associated Vulnerability in Development and Neovascular Remodeling

eSIG-Net: Accurate prediction of single-mutation induced perturbations on protein interactions using a language model

Posted by dbos Rockefeller

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Li Zhao | Authors: Xingxin Pan, Aditya Shrawat, Sidharth Raghavan, Chuanpeng Dong, Yuntao Yang, Zhao Li, W. Jim Zheng, S. Gail Eckhardt, Erxi Wu, Juan I Fuxman Bass, Daniel F Jarosz, Sidi Chen, Daniel J McGrail, Gloria M Sheynkman, Jason […]


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Spatially modulated morphotropic phase boundaries in a compressively strained multiferroic thin film

Posted by klaurent Cornell

Kavli Affiliate: Darrell Schlom | Summary:The coexisting rhombohedral-like (R’, MA) and tetragonal-like (T’, MC) monoclinic phases in compressively strained bismuth ferrite thin films exhibit exceptional piezoelectric and magnetic properties. While previous studies have largely focused on probing the morphotropic phase boundaries (MPBs) comprising ordered R’/T’ twins, their self-organizing structures remain not fully explored. Here, we […]


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A Novel Method to Construct Frequency-Domain Gravitational Waveform for Accelerating Sources

Posted by klaurent Peking

Kavli Affiliate: Xian Chen| Summary: Accurately modeling the inspiral-merger-ringdown (IMR) signal of coalescing compact objects is essential for the test of general relativity. However, it is known that astrophysical environments can distort gravitational-wave (GW) signal and, if ignored, may bias parameter estimation or even our understanding of gravity. Previous studies suggest that various astrophysical environmental […]


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Radiative Feedback in Population III Protostellar Growth: The Impact of HI Shielding

Posted by klaurent MIT

Kavli Affiliate: Mark Vogelsberger | Summary:We present a suite of radiation-magnetohydrodynamics simulations from the POPSICLE project that follow the long-term growth (~50 kyr) of primordial protostars while self-consistently coupling radiation, turbulence, and magnetic fields. The simulation suite is designed to quantify the relative impacts of the pathways of radiative feedback in Pop III stars – […]


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Optimisation of calibration sources for global 21-cm experiments: the REACH case

Posted by klaurent Cambridge

Kavli Affiliate: George Efstathiou | Summary:The spin-flip 21-cm signal from the Cosmic Dawn and the Epoch of Reionization is an essential probe of the conditions that led to the formation of the first luminous objects in the early Universe. However, its detection remains a major challenge owing to its low strength compared to the bright […]


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The SPHEREx Instrument: Calibration, testing and performance measurements of the NIR 2 spectroscopic surveyor from the laboratory to in-orbit commissioning

Posted by klaurent Caltech

Kavli Affiliate: James Bock | Summary:The SPHEREx near-infrared space telescope is an all-sky spectroscopic survey mission launched on March 12th, 2025 UTC. In addition to providing the community with a spectral database applicable to a wide range of investigations, it is optimized to address three core science goals: to survey the large scale structure of […]


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High dimensional alpha test for linear factor pricing model with $L_q$-norm

Posted by klaurent Peking

Kavli Affiliate: Feng Long| Summary: We consider testing zero pricing errors in high-dimensional linear factor pricing models. Existing methods are mainly based on either an $L_2$ statistic, which is effective under dense alternatives, or an $L_infty$ statistic, which is powerful under very sparse alternatives. To bridge these two regimes, we develop a class of $L_q$-based […]


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Direct N-body simulations of rotating and extremely massive Population III star clusters

Posted by klaurent Peking

Kavli Affiliate: Rainer Spurzem | Summary:Aims. We present eight direct N-body simulations with NBODY6++GPU of extremely massive, initially rotating Population III star clusters with 1.01 x 10^5 stars. Methods. Our models include primordial binaries, a continuous initial mass function, differential rotation, tidal mass loss, updated fitting formulae for extremely massive metal-poor Population III stars, and […]


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Direct N-body simulations of rotating and extremely massive Population III star clusters

Posted by klaurent Peking

Kavli Affiliate: Rainer Spurzem | Summary:Aims. We present eight direct N-body simulations with NBODY6++GPU of extremely massive, initially rotating Population III star clusters with 1.01 x 10^5 stars. Methods. Our models include primordial binaries, a continuous initial mass function, differential rotation, tidal mass loss, updated fitting formulae for extremely massive metal-poor Population III stars, and […]


Continue.. Direct N-body simulations of rotating and extremely massive Population III star clusters